WordNet

a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

PrepTutorEJDIC

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Effect of sphingosine 1-phosphate (S1P) receptor agonists FTY720 and CYM5442 on atherosclerosis development in LDL receptor deficient (LDL-R⁻/⁻) mice.

Poti F, Costa S, Bergonzini V, Galletti M, Pignatti E, Weber C, Simoni M, Nofer JR.SourceDepartment of Medicine, Endocrinology, Metabolism and Geriatrics, University of Modena and Reggio Emilia, Modena, Italy.
Vascular pharmacology.Vascul Pharmacol.2012 Aug 19;57(1):56-64. Epub 2012 Mar 20.
OBJECTIVES: Sphingosine 1-phosphate (S1P)--a lysosphingolipid present in HDL--exerts atheroprotective effects in vitro, while FTY720, a non-selective S1P mimetic inhibits atherosclerosis in LDL receptor-deficient (LDL-R⁻/⁻) mice under conditions of severe hypercholesterolemia. We here examined t
PMID 22459073

Sphingosine 1-phosphate receptor activation enhances BMP-2-induced osteoblast differentiation.

Sato C, Iwasaki T, Kitano S, Tsunemi S, Sano H.SourceDivision of Rheumatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2012 Jun 22;423(1):200-5. Epub 2012 May 31.
We previously demonstrated that sphingosine 1-phosphate (S1P) receptor-mediated signaling induced proliferation and prostaglandin productions by synovial cells from rheumatoid arthritis (RA) patients. In the present study we investigated the role of S1P receptor-mediated signaling for osteoblast dif
PMID 22659743

Sphingosylphosphorylcholine and lysosulfatide have inverse regulatory functions in monocytic cell differentiation into macrophages.

Yamamoto Hiroshi,Naito Yuko,Okano Maho,Kanazawa Takayuki,Takematsu Hiromu,Kozutsumi Yasunori
Archives of biochemistry and biophysics 506(1), 83-91, 2011-02-01
… Thus SPC utilizes G-protein coupled receptor. …
NAID 120002770476

Cardiovascular Protective Effects of Traditional Chinese Medicine Bak Foong Pills in Spontaneously Hypertensive Rats(Pharmacology)

ZHOU Qin,ROWLANDS Dewi Kenneth,GOU Yu Lin,TSANG Lai Ling,CHUNG Yiu Wa,CHAN Hsiao Chang
Biological & pharmaceutical bulletin 26(8), 1095-1099, 2003-08-01
… Micro-array analysis of brain tissue showed altered expression of acetylcholine and lysosphingolipid receptor genes that are known to regulate blood pressure. …
NAID 110003655057