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the formation of lymphocytes in the bone marrow and lymph nodes and thymus and spleen

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1. 成人外傷患者における脾損傷のマネージメント management of splenic injury in the adult trauma patient
2. 同種造血細胞移植後の免疫再構築のための戦略 strategies for immune reconstitution following allogeneic hematopoietic cell transplantation
3. 脾腫およびその他の脾疾患を有する成人患者に対するアプローチ approach to the adult patient with splenomegaly and other splenic disorders
4. 放射線関連肉腫 radiation associated sarcomas

Defective Endochondral Ossification-Derived Matrix and Bone Cells Alter the Lymphopoietic Niche in Collagen X Mouse Models.

Sweeney E, Roberts D, Lin A, Guldberg R, Jacenko O.Source1 Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania , Philadelphia, Pennsylvania.
Stem cells and development.Stem Cells Dev.2013 Jun 18. [Epub ahead of print]
Despite the appreciated interdependence of skeletal and hematopoietic development, the cell and matrix components of the hematopoietic niche remain to be fully defined. Utilizing mice with disrupted function of collagen X (ColX), a major hypertrophic cartilage matrix protein associated with endochon
PMID 23656481

Region-specific Etv2 ablation revealed the critical origin of hemogenic capacity from Hox6-positive caudal-lateral primitive mesoderm.

Kataoka H, Hayashi M, Kobayashi K, Ding G, Tanaka Y, Nishikawa S.SourceLaboratory for Stem Cell Biology, RIKEN Center for Developmental Biology, Kobe, Japan; PRESTO, Japan Science and Technology Agency, Saitama, Japan. Electronic address: kataokah@cdb.riken.jp.
Experimental hematology.Exp Hematol.2013 Jun;41(6):567-581.e9. doi: 10.1016/j.exphem.2013.02.009. Epub 2013 Feb 21.
Hematopoietic cells (HPCs) develop from hemogenic endothelial cells (ECs), a specialized type of ECs undergoing hematopoietic transition. However, the mesoderm origin for hemogenic ECs or HPCs has not been clarified. To examine the origin for hemogenic mesoderm, we inactivated Etv2, a master regulat
PMID 23438573

Histological characterization of bone marrow in ectopic bone, induced by devitalized Saos-2 human osteosarcoma cells.

Nahar NN, Tague SE, Wang J, Danley M, Garimella R, Anderson HC.SourceDepartments of Pathology and Laboratory Medicine, The University of Kansas Medical Center Kansas City, KS, USA.
International journal of clinical and experimental medicine.Int J Clin Exp Med.2013;6(2):119-25. Epub 2013 Jan 26.
Devitalized Saos-2, cultured human osteosarcoma cells, or guanidinium-hydrochloride (GuHCl) extracts of these cells, induce ectopic bone and marrow formation when implanted subcutaneously in Nu/Nu mice. The aim of the present study was to characterize the bone marrow induced by Saos-2 cell extracts,
PMID 23386915

Effects of four-week feed restriction on toxicological parameters in beagle dogs

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Experimental Animals advpub(0), 2015
… The principal outcomes were: decreased body weight and water consumption, ECG changes (decreased heart rate and prolonged QTc), and hematopoietic and lymphopoietic suppression (decreased reticulocyte ratio or white blood cell count in hematology, decreased nucleated cell count in bone marrow, decreased erythroid parameters in myelography, and hypocellularity of bone marrow and thymic atrophy in histopathology). …
NAID 130005063465

Coordinated regulation of transcription factors through Notch2 is an important mediator of mast cell fate

Sakata-Yanagimoto Mamiko,Nakagami-Yamaguchi Etsuko,Saito Toshiki,Kumano Keiki,Yasutomo Koji,Ogawa Seishi,Kurokawa Mineo,Chiba Shigeru
Proceedings of the National Academy of Sciences of the United States of America 105(22), 7839-7844, 2008-06
… Notch signaling plays a fundamental role in the lymphopoietic compartment, but its role in myeloid differentiation is less clear. …
NAID 120001356288

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Journal of radiation research 49(1), 83-91, 2008-01-15
… The risks for four cancers, leukemia, lymphopoietic cancers (LHC), lung cancer and mesothelioma, were studied in workers from shipyards involved in nuclear powered ship overhauls. …
NAID 110006570531