lymphocyte function associated antigen-1

出典: meddic

LFA- 1
LFA- 1

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英文文献

  • Aggregatibacter actinomycetemcomitans leukotoxin induces cytosol acidification in LFA-1 expressing immune cells.
  • Balashova N1, Dhingra A2, Boesze-Battaglia K2, Lally ET1.
  • Molecular oral microbiology.Mol Oral Microbiol.2016 Feb;31(1):106-14. doi: 10.1111/omi.12136. Epub 2015 Oct 16.
  • Studies have suggested that Aggregatibacter actinomycetemcomitans leukotoxin (LtxA) kills human lymphocyte function-associated antigen 1 (LFA-1; CD11a/CD18)-bearing immune cells through a lysosomal-mediated mechanism. Lysosomes are membrane-bound cellular organelles that contain an array of acid hyd
  • PMID 26361372
  • Inhibition of LtxA toxicity by blocking cholesterol binding with peptides.
  • Brown AC1, Koufos E1, Balashova NV2, Boesze-Battaglia K3, Lally ET2.
  • Molecular oral microbiology.Mol Oral Microbiol.2016 Feb;31(1):94-105. doi: 10.1111/omi.12133. Epub 2015 Oct 12.
  • The leukotoxin (LtxA) produced by Aggregatibacter actinomycetemcomitans kills host immune cells, allowing the bacterium to establish an ecological niche in the upper aerodigestive tract of its human host. The interaction of LtxA with human immune cells is both complex and multifaceted, involving mem
  • PMID 26352738
  • Lung ICAM-1 and ICAM-2 support spontaneous intravascular effector lymphocyte entrapment but are not required for neutrophil entrapment or emigration inside endotoxin-inflamed lungs.
  • Petrovich E1, Feigelson SW1, Stoler-Barak L1, Hatzav M1, Solomon A1, Bar-Shai A1, Ilan N1, Li JP1, Engelhardt B1, Vlodavsky I1, Alon R2.
  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology.FASEB J.2016 Jan 28. pii: fj.201500046. [Epub ahead of print]
  • The pulmonary vasculature constitutively expresses the integrin lymphocyte function-associated antigen-1 ligands intercellular adhesion molecule (ICAM)-1 and -2. In this study, effector T cells were temporarily entrapped by the lung vasculature on their way to inflamed lymph nodes, and this entrapme
  • PMID 26823454

和文文献

  • Soluble ICAM-1 secretion and its functional role as an autocrine growth factor in nasal NK/T cell lymphoma cells.
  • 〈原著〉AIDS関連中枢神経原発悪性リンパ腫の発生におけるリンパ球機能関連抗原-1(LFA-1)の関与
  • 近畿大学医学雑誌 = Medical journal of Kinki University 37(1-2), 45-52, 2012-03-01
  • NAID 120005736662
  • OP-046-4 細胞内ポリアミンによるLFA-1(Lymphocyte Function-Associated Antigen-1)発現変化のメカニズムに関する検討(免疫-2,一般口演,第110回日本外科学会定期学術集会)

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★リンクテーブル★
関連記事associate」「function」「antigen」「lymphocyte」「functioning

associate」

  [★]

  • vt.
  • 結合する、連合させる。連想によって結びつける。(人を)仲間/友達などとしての関係に置く。(化)会合させる
  • vi.
  • 仲間/友人などとして交際する(with)。一つにまとめる、連合する
  • n.
  • 仕事仲間、提携者、同僚。友人、朋友。準会員。従業員、社員
  • 密接な蒸す偽付きのある物、付随する物、つきもの。準国家
  • 連想によって心に浮かぶ言葉/思い、連想物
  • adj.
  • 仲間の、同僚の。製紙機械員に次ぐ資格の
  • 付随する、連想される
accompanyassociationassociativeattachbearingbindbindingbondbondingcoassemblecolleaguecombineconjoinconjugateconjugationconjunctionconnectconnectioncorrelatecorrelationcoupledockengageengagementfederationimplicationjoinjointligatelinklinkagepeerpertinentreferencerelaterelationrelationshiprelativerelevancerelevantsymphysialunion

WordNet   license wordnet

「having partial rights and privileges or subordinate status; "an associate member"; "an associate professor"」

WordNet   license wordnet

「a person who joins with others in some activity or endeavor; "he had to consult his associate before continuing"」

WordNet   license wordnet

「a person with subordinate membership in a society, institution, or commercial enterprise; "associates in the law firm bill at a lower rate than do partners"」

WordNet   license wordnet

「any event that usually accompanies or is closely connected with another; "first was the lightning and then its thunderous associate"」

PrepTutorEJDIC   license prepejdic

「〈人〉'を'(…の)『仲間に加える』,(…に)連合させる《+『名』〈人〉+『with』+『名』》 / (…と)…'を'結びつけて考える(起こす)《+『名』+『with』+『名』》 / (…と)『仲間になる』,交際する《+『with』+『名』》 / (…と)合体する,提携する《+『with』+『名』》 / 『仲間』,『同僚』;組合員 / 準会員 / 付属物;連想されるもの / 連合した;仲間の,同僚の / 補助の,準…」

WordNet   license wordnet

「make a logical or causal connection; "I cannot connect these two pieces of evidence in my mind"; "colligate these facts"; "I cannot relate these events at all"」
tie in, relate, link, colligate, link up, connect


function」

  [★]

  • n.
survival as a function of HbA1c in people with type 2 diabetes HbA1cの機能を考慮(指標に)した2型糖尿病の患者の生存(予後)
Figure 2A shows survival as a function of device removal during index hpspitalization, censored at 1 year or date of last contact. (Figure2Aはは最初の入院中における心臓デバイス除去に関する生存曲線で退院後1年もしくは最後の接触で打ち切っている)
  • v.
  • 機能する
functionalfunctional groupfunctionalisefunctionalizeoperate

WordNet   license wordnet

「perform as expected when applied; "The washing machine won''t go unless it''s plugged in"; "Does this old car still run well?"; "This old radio doesn''t work anymore"」
work, operate, go, run

WordNet   license wordnet

「(mathematics) a mathematical relation such that each element of a given set (the domain of the function) is associated with an element of another set (the range of the function)」
mathematical function, single-valued function, map, mapping

WordNet   license wordnet

「a relation such that one thing is dependent on another; "height is a function of age"; "price is a function of supply and demand"」

WordNet   license wordnet

「the actions and activities assigned to or required or expected of a person or group; "the function of a teacher"; "the government must do its part"; "play its role"」
office, part, role

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「what something is used for; "the function of an auger is to bore holes"; "ballet is beautiful but what use is it?"」
purpose, role, use

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「a formal or official social gathering or ceremony; "it was a black-tie function"」

PrepTutorEJDIC   license prepejdic

「(人・物の果たすべき)『働き』,機能,役目;《しばしば複数形で》職務 / (公式の)儀式,《話》大きな催し(集まり),式典 / (数学で)関数 / 〈機械などが〉『機能を果たす』,動く / (…の)役目をする,代用となる《+『as』+『名』》」


antigen」

  [★]

  • n.

WordNet   license wordnet

「any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)」

PrepTutorEJDIC   license prepejdic

「抗原(生物の体内にはいって免疫体を作る物質)」


lymphocyte」

  [★] リンパ球

lymphocytes&development

WordNet   license wordnet

「an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection」
lymph cell


functioning」

  [★]

WordNet   license wordnet

「performing or able to perform its regular function; "a functioning flashlight"」




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