WordNet

give a definition for the meaning of a word; "Define `sadness"
show the form or outline of; "The tree was clearly defined by the light"; "The camera could define the smallest object" (同)delineate
determine the nature of; "What defines a good wine?"
clearly characterized or delimited; "lost in a maze of words both defined and undefined"; "each child has clearly defined duties"
showing clearly the outline or profile or boundary; "hills defined against the evening sky"; "the setting sun showed the outlined figure of a man standing on the hill" (同)outlined
any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection (同)lymph cell

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〈語・句〉'を'『定義する』,‘の'意味で明らかにする / 〈本質・意義・立場〉'を'『明らかにする』,特徴づける / …‘の'輪郭をはっきりさせる / …‘の'限界(範囲)を決める
抗原(生物の体内にはいって免疫体を作る物質)

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1. BおよびTリンパ球の正常な発生 normal b and t lymphocyte development
2. リンパ球増加症またはリンパ球減少症を有する患者へのアプローチ approach to the patient with lymphocytosis or lymphocytopenia
3. 造血細胞移植後の再発の予防および治療のための免疫療法 immunotherapy for the prevention and treatment of relapse following hematopoietic cell transplantation
4. 大顆粒T細胞リンパ球性白血病の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of t cell large granular lymphocyte leukemia
5. 胎児および新生児における免疫細胞の発達 the development of immune cells in the fetus and neonate

Computer-aided design of T-cell epitope-based vaccines: addressing population coverage.

Oyarzun P1, Kobe B2.
International journal of immunogenetics.Int J Immunogenet.2015 Oct;42(5):313-21. doi: 10.1111/iji.12214. Epub 2015 Jul 24.
Epitope-based vaccines (EVs) make use of short antigen-derived peptides corresponding to immune epitopes, which are administered to trigger a protective humoral and/or cellular immune response. EVs potentially allow for precise control over the immune response activation by focusing on the most rele
PMID 26211755

A novel multicolor immunostaining method using ethynyl deoxyuridine for analysis of in situ immunoproliferative response.

Kitazawa Y1, Ueta H, Hünig T, Sawanobori Y, Matsuno K.
Histochemistry and cell biology.Histochem Cell Biol.2015 Sep;144(3):195-208. doi: 10.1007/s00418-015-1329-z. Epub 2015 May 15.
Immune responses are generally accompanied by antigen presentation and proliferation and differentiation of antigen-specific lymphocytes (immunoproliferation), but analysis of these events in situ on tissue sections is very difficult. We have developed a new method of simultaneous multicolor immunof
PMID 25976155

Major Histocompatibility Complex class IIB polymorphism in an ancient Spanish breed.

Atlija M1, Gutíerrez-Gil B, Arranz JJ, Semmer J, Stear MJ, Buitkamp J.
Immunogenetics.Immunogenetics.2015 Sep;67(9):531-7. doi: 10.1007/s00251-015-0856-z. Epub 2015 Jul 17.
Genes from the Major Histocompatibility Complex class II region are involved in the presentation of antigens. Therefore, they have the key role in regulating the immune response and in the resistance to infections. We investigated the Major Histocompatibility Complex class IIB genes, DRB and DQB, in
PMID 26184839

Development of a Novel In Silico Docking Simulation Model for the Fine HIV-1 Cytotoxic T Lymphocyte Epitope Mapping

Mori Masahiko,Matsuki Kei,Maekawa Tomoyuki,Tanaka Mari,Sriwanthana Busarawan,Yokoyama Masaru,Ariyoshi Koya
PLoS ONE 7(7), e41703, 2012-07-27
… It was applied to predict 52 HIV best-defined CTL epitopes from 15-mer overlapping peptides, and its predictive ability was compared with the HLA binding motif-based program of HLArestrictor. …
NAID 120005052723

Clinical and genetic characteristics of autoimmune polyglandular syndrome type 3 variant in the Japanese population

Horie Ichiro,Kawasaki Eiji,Ando Takao,Kuwahara Hironaga,Abiru Norio,Usa Toshiro,Yamasaki Hironori,Ejima Eri,Kawakami Atsushi
Journal of Clinical Endocrinology & Metabolism 97(6), E1043-E1050, 2012-06
… Objective: Type 1 diabetes (T1D) iscommonlyassociated withautoimmunethyroid disease (AITD),and the occurrence of both T1D and AITD in a patient is defined as autoimmune polyglandular syndrome type 3 variant (APS3v). … Among the two major susceptible human leukocyte antigen (HLA) class II haplotypes in Japanese T1D, DRB1*0405- DQB1*0401, but not DRB1*0901-DQB1*0303, was associated with APS3v patients. …
NAID 120004754247

Possible association of cytotoxic T lymphocyte antigen-4 genetic polymorphism with liver damage of primary biliary cirrhosis in Japan

菅野有紀子,雷毅,物江恭子,斉藤広信,高橋敦史,入澤篤志,大平弘正
Fukushima journal of medical science 52(2), 79-85, 2006-12-01
… Cytotoxic T lymphocyte antigen-4 (CTLA-4) is an important inhibitor of T-lymphocyte response. … CTLA-4 exon 1 (+49) polymorphism was defined using a polymerase chain reaction-restriction fragment length polymorphism with Bst71I restriction enzyme. …
NAID 10026159880