WordNet

an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection (同)lymph cell

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1. 赤血球移植前試験 pretransfusion testing for red blood cell transfusion
2. 交差適合試験での不適合 the incompatible crossmatch
3. 幼児および小児における赤血球輸血：血液製剤の選択 red blood cell transfusion in infants and children selection of blood products
4. 移植免疫 transplantation immunobiology
5. 腎移植におけるHLAとABOの感作および脱感作 hla and abo sensitization and desensitization in renal transplantation

Variable HLA expression on deceased donor lymphocytes: Not all crossmatches are created equal.

Badders JL1, Jones JA1, Jeresano ME1, Schillinger KP1, Jackson AM2.
Human immunology.Hum Immunol.2015 Nov;76(11):795-800. doi: 10.1016/j.humimm.2015.09.029. Epub 2015 Oct 9.
Flow cytometric crossmatch tests are used to detect donor-specific antibody and determine eligibility for transplantation. Crossmatch sensitivity is dependent on lymphocyte quality, to include HLA expression on the cell surface. The impact of HLA expression variability on crossmatch reactivity was e
PMID 26455297

Improved flow cytometry based cytotoxicity and binding assay for clinical antibody HLA crossmatching.

Alheim M1, Paul PK2, Hauzenberger DM2, Wikström AC3.
Human immunology.Hum Immunol.2015 Nov;76(11):849-57. doi: 10.1016/j.humimm.2015.09.047. Epub 2015 Sep 30.
The presence of preformed donor-specific HLA antibodies leads to early antibody mediated kidney allograft rejection. Therefore, detection and avoidance of donor reactive HLA antibodies prior to transplantation is of outmost importance in order to minimize the risk of rejection. Detection of pre-form
PMID 26429307

Bortezomib for refractory acute antibody-mediated rejection in kidney transplant recipients. A single-center case series.

De Sousa-Amorim E1, Revuelta I1,2, Diekmann F1,2, Cofan F1, Lozano M3, Cid J3, Palou E4, Sole M5, Campistol JM1,2, Oppenheimer F1,2.
Nephrology (Carlton, Vic.).Nephrology (Carlton).2015 Oct 22. doi: 10.1111/nep.12659. [Epub ahead of print]
AIM: Acute antibody-mediated rejection (AMBR) after kidney transplantation (KT) is associated with poor allograft survival. Current therapies for ABMR are able to deplete B-lymphocytes but do not target plasma cells. Bortezomib is a proteasome inhibitor that can eliminate plasma cells and has demons
PMID 26492594

湯沢賢治
Major Histocompatibility Complex 21(2), 105-118, 2014
腎移植の成績は，免疫抑制剤の進歩により，格段に良くなった。それまでは，拒絶反応を少しでも少なくするために組織適合性HLAの一致が求められ，適合者が選択されてきた。しかし，免疫抑制剤の進歩により，HLAの適合度が腎移植成績に与える効果は低くなった。その後，高感度の抗HLA抗体検査が可能となり，組織適合性検査の重要性が見直されてきている。腎移植における組織適合性検査の重要性を認識できるよう，腎移植の現 …
NAID 130004684551

Complement-dependent cytotoxic crossmatchおよびFlow cytometric crossmatchの結果の乖離についての検討―補体結合性HLA抗体の検出―

石塚敏,安尾美年子,石田悠梨,二ツ山和也,吉野敏栄,岩藤和広,中島一朗,渕之上昌平
移植 48(1), 033-041, 2013
… 【Objective】There may be a discrepancy in the results between the complement-dependent cytotoxic crossmatch test (CDC-XM) and the flow cytometry crossmatch test (FCXM) for the detection of HLA antibodies (HLA-Abs). … The specificity of the Abs in these serums was determined using LABScreen and lymphocyte cells (LCCs) of a third party that had the same antigen as the specified Abs that were selected. …
NAID 130004698755