WordNet

unrefined in character; "low comedy"
an air mass of lower pressure; often brings precipitation; "a low moved in over night bringing sleet and snow" (同)depression
a low level or position or degree; "the stock market fell to a new low"
used of sounds and voices; low in pitch or frequency (同)low-pitched
very low in volume; "a low murmur"; "the low-toned murmur of the surf" (同)low-toned
in a low position; near the ground; "the branches hung low"
less than normal in degree or intensity or amount; "low prices"; "the reservoir is low"
literal meanings; being at or having a relatively small elevation or upward extension; "low ceilings"; "low clouds"; "low hills"; "the sun is low"; "low furniture"; "a low bow"
(statistics) a coefficient assigned to elements of a frequency distribution in order to represent their relative importance (同)weighting
sports equipment used in calisthenic exercises and weightlifting; it is not attached to anything and is raised and lowered by use of the hands and arms (同)free weight, exercising weight
an artifact that is heavy
the vertical force exerted by a mass as a result of gravity
the relative importance granted to something; "his opinion carries great weight"; "the progression implied an increasing weightiness of the items listed" (同)weightiness
an oppressive feeling of heavy force; "bowed down by the weight of responsibility"
have a certain weight
determine the weight of; "The butcher weighed the chicken" (同)librate
to be oppressive or burdensome; "weigh heavily on the mind", "Something pressed on his mind" (同)press
relating to simple or elementary organization; "proceed by more and more detailed analysis to the molecular facts of perception"--G.A. Miller
relating to or produced by or consisting of molecules; "molecular structure"; "molecular oxygen"; "molecular weight is the sum of all the atoms in a molecule"
adjusted to reflect value or proportion; "votes weighted according to the size of constituencies"; "a law weighted in favor of landlords"; "a weighted average"

PrepTutorEJDIC

(高さ・位置が)『低い』,低い所にある / (価格・数量・程度などが)『低い』,少ない / (身分・地位などが)『低い』,卑しい / (人格・行為などが)『卑しい』,下劣な,下品な / 《補語にのみ用いて》(体が)『弱った』;元気のない,憂うつな / (供給が)不十分な;(…が)乏しい《+『in』(『on』)+『名』》 / (音・声が)低い,小さい / (生物が)下等な / 『低く』,低い所に / (価格・程度などが)『安く』,低く / 低い声(調子)で;静かに / 最低点,最低水準
(牛の)モーという鳴き声 / (牛が)モーと鳴く
〈u〉『重さ』,重量,目方;体重;《a weight》(…の)重さ《+of+名》 / 〈u〉重さ(重力が物体に及ぼす力) / 〈u〉衡法(重量を示す体係) / 〈c〉重量単位 / 〈c〉(はかりの)おもり,分銅;(一般に)重いもの,おもし / 〈u〉重要性,価値 / 〈u〉《しばしば a weight》精神的な重荷,負担 / (…で)…‘に'重荷を負わせる;…‘を'圧迫する;苦しめる《+名+with+名》 / …‘を'重くする
…‘の'『重さを計る』 / 〈ある重さ〉‘を'『計量する』,計る / (…と比較して)…‘を'『検討する』,考慮する〈+名 against+名〉 / 『重さがある』,目方がかかる / (…にとって)『重要である』,(‥に)重要糸される〈+with+名〉
分子の,分子による
《補語にのみ用いて》(…に)有利な《+toward+名》

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/05/19 14:07:53」(JST)

wiki en

Low-molecular-weight kininogen is a form of kininogen, which has been identified in mice,^[1] guinea pigs,^[2] and whales.^[3]

It is also found in humans.^[4]

References

^ Shesely E, Hu C, Alhenc-Gelas F, Meneton P, Carretero O (2006). "A second expressed kininogen gene in mice". Physiol Genomics 26 (2): 152–7. doi:10.1152/physiolgenomics.00244.2005. PMID 16837654.
^ Semba U, Umeda Y, Shibuya Y, Okabe H, Tanase S, Yamamoto T (2004). "Primary structures of guinea pig high- and low-molecular-weight kininogens". Int Immunopharmacol 4 (10-11): 1391–400. doi:10.1016/j.intimp.2004.06.003. PMID 15313436.
^ Semba U, Shibuya Y, Okabe H, Hayashi I, Yamamoto T (2000). "Whale high-molecular-weight and low-molecular-weight kininogens". Thromb Res 97 (6): 481–90. doi:10.1016/S0049-3848(99)00199-1. PMID 10704658.
^ Stefan Offermanns; Walter Rosenthal (2008). Encyclopedia of Molecular Pharmacology. Springer. pp. 673–. ISBN 978-3-540-38916-3. Retrieved 11 December 2010.

External links

Low-Molecular-Weight Kininogen at the US National Library of Medicine Medical Subject Headings (MeSH)

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 早期産低出生体重児の単胎分娩 delivery of the preterm low birth weight singleton fetus
2. 静脈血栓塞栓症に対する低分子ヘパリン low molecular weight heparin for venous thromboembolic disease
3. Therapeutic use of unfractionated heparin and low molecular weight heparin
4. 止血の概要 overview of hemostasis
5. 凝固検査の臨床使用 clinical use of coagulation tests

English Journal

Angiotensin-converting enzyme inhibitor-induced angioedema: A review of the literature.

Brown T1, Gonzalez J2, Monteleone C3.
Journal of clinical hypertension (Greenwich, Conn.).J Clin Hypertens (Greenwich).2017 Dec;19(12):1377-1382. doi: 10.1111/jch.13097. Epub 2017 Oct 10.
PMID 28994183

Hereditary angioedema: Assessing the hypothesis for underlying autonomic dysfunction.

Wu MA1, Casella F1, Perego F1, Suffritti C1, Afifi Afifi N1, Tobaldini E2, Zanichelli A1, Cogliati C1, Montano N2, Cicardi M1.
PloS one.PLoS One.2017 Nov 6;12(11):e0187110. doi: 10.1371/journal.pone.0187110. eCollection 2017.
PMID 29107952

The role of the kallikrein-kinin system, matrix metalloproteinases, and tissue inhibitors of metalloproteinases in the early restenosis of covered stents in the femoropopliteal arterial segment.

Rocha LA1, Piccinato CE2, Ribiero MS2, Becari C3, Joviliano RD2, Joviliano EE2.
Journal of vascular surgery.J Vasc Surg.2017 Jan;65(1):119-127. doi: 10.1016/j.jvs.2016.06.106. Epub 2016 Sep 22.
PMID 27667150

Japanese Journal

Expressions of Bradykinin B2-Receptor, Kallikrein and Kininogen mRNAs in the Heart Are Altered in Pressure-Overload Cardiac Hypertrophy in Mice

YAYAMA Katsutoshi,HIYOSHI Hiromi,OKAMOTO Hiroshi
Biological & pharmaceutical bulletin 24(1), 34-38, 2001-01-01
… The objectives of the present study were to define the effects of pressure-overload cardiac hypertrophy on cardiac levels of kininogen, kallikrein and bradykinin B2 receptor mRNAs. … The pressure-overload induced by aortic constriction produced cardiac hypertrophy in mice after 14 and 28 d, assessed from the increased ratios of heart weight to body weight and elevation of brain natriuretic peptide mRNA in the heart. …
NAID 110003638347

Tissue-Specific Expression of Rat Kininogen mRNAs

TAKANO Masaoki,SAKANAKA Fumie,YAYAMA Katsutoshi,OKAMOTO Hiroshi
Biological & pharmaceutical bulletin 23(10), 1239-1242, 2000-10-01
… To characterize the local kallikrein-kinin system, tissue distribution of mRNAs for kininogens, precursor proteins of kinins, such as high-molecular-weight (H-), low-molecular-weight (L-) and T-kininogens, were studied in the rat by means of reverse-transcription polymerase chain reaction (RT-PCR) using a fluorophore Cy5-labeled 5'-primer. … High levels of these three kininogen mRNAs were present in the liver. …
NAID 110003639862