lovastatin

出典: meddic

ロバスタチン

WordNet   license wordnet

「an oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate」
Mevacor

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/06/26 03:26:36」(JST)

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英文文献

  • A sensitive molecularly imprinted polymer based quartz crystal microbalance nanosensor for selective determination of lovastatin in red yeast rice.
  • Eren T1, Atar N2, Yola ML3, Karimi-Maleh H4.
  • Food chemistry.Food Chem.2015 Oct 15;185:430-6. doi: 10.1016/j.foodchem.2015.03.153. Epub 2015 Apr 11.
  • Lovastatin (LOV) is a statin, used to lower cholesterol which has been found as a hypolipidemic agent in commercial red yeast rice. In present study, a sensitive molecular imprinted quartz crystal microbalance (QCM) sensor was prepared by fabricating a self-assembling monolayer formation of allylmer
  • PMID 25952889
  • Influence of oxygen on lovastatin biosynthesis by Aspergillus terreus ATCC 20542 quantitatively studied on the level of individual pellets.
  • Bizukojc M1, Gonciarz J.
  • Bioprocess and biosystems engineering.Bioprocess Biosyst Eng.2015 Jul;38(7):1251-66. doi: 10.1007/s00449-015-1366-y. Epub 2015 Jan 28.
  • Despite oxygen is believed to be the most important environmental factor for any aerobic microbial process, the quantitative studies of its influence on growth and metabolite formation on the level of individual pellets formed by filamentous fungi were seldom performed. Never was it made for lovasta
  • PMID 25627471
  • Acute toxicological effects on the earthworm Eisenia fetida of 18 common pharmaceuticals in artificial soil.
  • Pino MR1, Val J2, Mainar AM3, Zuriaga E4, Español C5, Langa E6.
  • The Science of the total environment.Sci Total Environ.2015 Jun 15;518-519:225-37. doi: 10.1016/j.scitotenv.2015.02.080. Epub 2015 Mar 9.
  • Following soil applications of recycled water and biosolids, pharmaceutical residues can eventually enter the terrestrial environment. In vitro and in vivo assays have largely focused on the acute ecotoxicity of these compounds in aquatic systems. However, studies on the ecotoxicological effects of
  • PMID 25765375

和文文献

  • Inhibitory effects of clinical reagents having anti-oxidative activity on transforming growth factor-β1-induced expression of α-smooth muscle actin in human fetal lung fibroblasts
  • MATSUZAWA Yasuo,KAWASHIMA Tatsuo,YAMAZAKI Risa,YAMAURA Erika,MAKIYAMA Tomohiko,FUJINO Hiromichi,MURAYAMA Toshihiko
  • Journal of toxicological sciences 36(6), 733-740, 2011-12-01
  • NAID 10030036736
  • Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist.
  • Goto Tsuyoshi,Nagai Hiroyuki,Egawa Kahori,Kim Young-Il,Kato Sota,Taimatsu Aki,Sakamoto Tomoya,Ebisu Shogo,Hohsaka Takahiro,Miyagawa Hiroh,Murakami Shigeru,Takahashi Nobuyuki,Kawada Teruo
  • The Biochemical journal 438(1), 111-119, 2011-08-15
  • … In the presence of lovastatin, an HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitor, both intracellular FPP levels and PPARγ-target gene expressions were decreased. …
  • NAID 120004225537

関連リンク

一方、メバスタチンの効果に関心を寄せていたアメリカの大手製薬企業・メルク(MSD) 社は、遠藤からサンプルやデータの提供を受けながら独自に研究開発を進めた結果、 コウジカビの一種 (Aspergillus terreus) から新たなスタチンであるロバスタチンを分離 ...
Lovastatin (Merck's Mevacor) is a member of the drug class of statins, used in combination with diet, weight-loss, and exercise for lowering cholesterol ( hypolipidemic agent) in those with hypercholesterolemia to reduce risk of cardiovascular ...

関連画像

Synthesis of compounds 1 and 2Niacin/lovastatinLovastatin 20mgDescription Lovastatin-Strukturformel.pngDescription Lovastatin.svgLovastatin (Lovastatin, 1 alpha-Isomer


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