WordNet

not tight; not closely constrained or constricted or constricting; "loose clothing"; "the large shoes were very loose"
without restraint; "cows in India are running loose" (同)free
(of textures) full of small openings or gaps; "an open texture"; "a loose weave" (同)open
not tense or taut; "the old mans skin hung loose and grey"; "slack and wrinkled skin"; "slack sails"; "a slack rope" (同)slack
(of a ball in sport) not in the possession or control of any player; "a loose ball"
not carefully arranged in a package; "a box of loose nails"
not compact or dense in structure or arrangement; "loose gravel"
a soft thin (usually translucent) paper (同)tissue_paper
part of an organism consisting of an aggregate of cells having a similar structure and function
connecting or tending to connect; "connective remarks between chapters"; "connective tissue in animals"; "conjunctive tissue in plants"

PrepTutorEJDIC

『結んでない』,解けている,ばらの / 『解き放たれた』,自由な(free) / 『緩い』,だぶだぶの;ぐらぐらの / 『散漫な』,不正確な,あいまいな / 大ざっぱな,漠然とした / (行為などが)だらしのない,ふしだらな / (織物などが)目の粗い / …‘を'『放す』,自由にする(set free) / …‘を'緩める;〈結び目など〉‘を'解く / 〈矢・弾丸など〉‘を'放つ,発射する
〈U〉〈C〉(生物体の)『組織』 / 〈U〉〈C〉『薄織物』 / 〈U〉〈C〉水を吸収する柔らかな薄紙 / 〈C〉カーボンコピー用薄紙 / 〈C〉《a ~》(…を)織り交ぜて作ったもの《+of+名》 / =tissue paper
結びつける,連結の,接続の / 連結辞(接続詞・関係代名詞など)
便所

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/11/07 11:01:18」(JST)

wiki en

Loose connective tissue is a category of connective tissue which includes areolar tissue, reticular tissue, and adipose tissue. Loose connective tissue is the most common type of connective tissue in vertebrates. It holds organs in place and attaches epithelial tissue to other underlying tissues. For example, it forms telae, such as the tela submucosa and tela subserosa, which connect mucous and serous membranes to the muscular layer. It also surrounds the blood vessels and nerves. Cells called fibroblasts are widely dispersed in this tissue; they are irregular branching cells that secrete strong fibrous proteins and proteoglycans as an extracellular matrix. The cells of this type of tissue are generally separated by quite some distance by a gelatinous substance primarily made up of collagenous and elastic fibers.

Loose connective tissue is named based on the weave and type of its constituent fibers. There are three main types of connective tissue fiber:

Collagenous fibers: collagenous fibers are made of collagen and consist of bundles of fibrils that are coils of collagen molecules.
Elastic fibers: elastic fibers are made of elastin and are "stretchable."
Reticular fibers: reticular fibers consist of one or more types of very thin collagen fibers. They join connective tissues to other tissues.

Areolar tissue (/əˈriːələr/ or /ˌɛəriˈoʊlər, ˌær-/^[1]^[2]) is a common type of loose connective tissue (and the most widely distributed type of connective tissue in vertebrates). It is so named because its fibers are far enough apart to leave ample open space for interstitial fluid in between (areola is Latin for a "little open space"). It is strong enough to bind different tissue types together, yet soft enough to provide flexibility and cushioning. It exhibits interlacing,^[3] loosely organized fibers,^{[citation needed]} abundant blood vessels, and significant empty space filled with interstitial fluid. Many adjacent epithelial tissues (which are avascular) get their nutrients from the interstitial fluid of areolar tissue; the lamina propria is areolar in many body locations. Its fibers run in random directions and are mostly collagenous, but elastic and reticular fibers are also present. Areolar tissue is highly variable in appearance. In many serous membranes, it appears as a loose arrangement of collagenous and elastic fibers, scattered cells of various types; abundant ground substance; numerous blood vessels. In the skin and mucous membranes, it is more compact and sometimes difficult to distinguish from dense irregular connective tissue.

Usually "loose connective tissue" is considered a parent category that includes the mucous connective tissue of the fetus, areolar connective tissue, reticular connective tissue, and adipose tissue.^[4]

Location

It may be found in tissue sections from almost every part of the body. It surrounds blood vessels and nerves and penetrates with them even into the small spaces of muscles, tendons, and other tissues. It may likewise be present in the mediastinal extremities. Nearly every epithelium rests on a layer of areolar tissue, whose blood vessels provide the epithelium with nutrition, waste removal, and a ready supply of infection-fighting leukocytes in times of need. Because of the abundance of open, fluid-filled space, leukocytes can move about freely in areolar tissue and can easily find and destroy pathogens.

The areolar tissue is found beneath the dermis layer and is also underneath the epithelial tissue of all the body systems that have external openings.

It is also a component of the lamina propria of the digestive and respiratory tracts, the mucous membranes of reproductive and urinary systems, the stroma of glands, and the hypodermis of the skin. It is also found in the mesentery which is surrounding the intestine.

Composition

Schematic representation of the composition of loose connective tissue

It is a pliable, mesh-like tissue with a fluid matrix and functions to cushion and protect body organs.

Fibroblasts are widely dispersed in this tissue; they are irregular branching cells that secrete strong fibrous proteins and proteoglycans as an extracellular matrix.

The cells of this type of tissue are generally connected by a gelatinous substance known as ground substance primarily made up of collagenous and elastic fibers.

Function

Areolar connective tissues hold organs in place and attaches epithelial tissue to other underlying tissues. It also serves as a reservoir of water and salts for surrounding tissues. Almost all cells obtain their nutrients from and release their wastes into areolar connective tissue.

Classification

Loose connective tissue is named based on the "weave" and type of its constituent fibers. There are three main types:

Collagenous fibers: collagenous fibers are made of collagen and consist of bundles of fibrils that are coils of collagen molecules.
Elastic fibers: elastic fibers are made of elastin and are "stretchable."
Reticular fibers: reticular fibers consist of one or more types of very thin collagen fibers. They join connective tissues to other tissues.

References

^ "Areolar". Merriam-Webster Dictionary. Retrieved 2016-01-21.
^ "Areolar". Oxford Dictionaries. Oxford University Press. Retrieved 2016-01-21.
^ "areolar tissue" at Dorland's Medical Dictionary
^ "Blue Histology - Connective Tissues". Retrieved 2008-12-05.

UpToDate Contents

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1. 未分化型の全身性リウマチ性（結合組織）疾患およびオーバーラップ症候群 undifferentiated systemic rheumatic connective tissue diseases and overlap syndromes
2. 混合性結合組織病の臨床症状 clinical manifestations of mixed connective tissue disease
3. 混合性結合組織病の定義および診断 definition and diagnosis of mixed connective tissue disease
4. 混合性結合組織病の予後および治療 prognosis and treatment of mixed connective tissue disease
5. 甲状腺疾患と膠原病 thyroid disorders and connective tissue disease

English Journal

An Immunohistochemical Study of Matrix Components in Early-Stage Vascular Canals Within Mandibular Condylar Cartilage in Midterm Human Fetuses.

Shibata S1, Morita T1, Yokohama-Tamaki T1, Murakami G2, Cho BH3.
Anatomical record (Hoboken, N.J. : 2007).Anat Rec (Hoboken).2015 Sep;298(9):1560-71. doi: 10.1002/ar.23175. Epub 2015 Jun 22.
Matrix components of vascular canals (VCs) in human fetal mandibular condylar cartilage (15-16 weeks of gestation) were analyzed by immunohistochemistry. Prevascular canals (PVCs), consisting of spindle-shaped cells without capillary invasion, were observed within the cartilage. Intense immunoreacti
PMID 25989382

NBAS mutations cause a multisystem disorder involving bone, connective tissue, liver, immune system, and retina.

Garcia Segarra N1, Ballhausen D1, Crawford H2, Perreau M3, Campos-Xavier B1, van Spaendonck-Zwarts K4, Vermeer C5, Russo M6, Zambelli PY7, Stevenson B8, Royer-Bertrand B9, Rivolta C9, Candotti F3, Unger S9, Munier FL10, Superti-Furga A11, Bonafé L1.
American journal of medical genetics. Part A.Am J Med Genet A.2015 Aug 19. doi: 10.1002/ajmg.a.37338. [Epub ahead of print]
We report two unrelated patients with a multisystem disease involving liver, eye, immune system, connective tissue, and bone, caused by biallelic mutations in the neuroblastoma amplified sequence (NBAS) gene. Both presented as infants with recurrent episodes triggered by fever with vomiting, dehydra
PMID 26286438

Japanese Journal

陰圧閉鎖療法と嚥下・頸部運動リハビリを行った頸部壊死性筋膜炎

頭頸部外科 27(2), 179-185, 2017
NAID 130006210704

A nasal osteoma with an acute course in a Japanese Black heifer

Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ 79(7), 1220-1224, 2017
NAID 130005808392

顎関節穿刺吸引細胞診が有効であった滑膜軟骨腫症の1例

日本口腔診断学会雑誌 28(1), 5-10, 2015
NAID 130005075353

Related Pictures

★リンクテーブル★

リンク元	「疎性結合組織」
関連記事	「connective」「loose」

「疎性結合組織」

Loose connective tissue
	Section of derimis. The papillary dermis consists of loose connective tissue.
Details
Identifiers
Latin	textus connectivus laxus
Code	TH H2.00.03.1.00002
TA	A04.5.02.020; A16.0.03.006
FMA	19783
	Anatomical terminology [edit on Wikidata]