WordNet
- primarily temporal sense; being or indicating a relatively great or greater than average duration or passage of time or a duration as specified; "a long life"; "a long boring speech"; "a long time"; "a long friendship"; "a long game"; "long ago"; "an hour long"
- (of speech sounds or syllables) of relatively long duration; "the English vowel sounds in `bate, `beat, `bite, `boat, `boot are long"
- for an extended distance
- for an extended time or at a distant time; "a promotion long overdue"; "something long hoped for"; "his name has long been forgotten"; "talked all night long"; "how long will you be gone?"; "arrived long before he was expected"; "it is long after your bedtime"
- having or being more than normal or necessary:"long on brains"; "in long supply"
- holding securities or commodities in expectation of a rise in prices; "is long on coffee"; "a long position in gold"
- involving substantial risk; "long odds"
- of relatively great height; "a race of long gaunt men"- Sherwood Anderson; "looked out the long French windows"
- primarily spatial sense; of relatively great or greater than average spatial extension or extension as specified; "a long road"; "a long distance"; "contained many long words"; "ten miles long"
- name formally or designate with a term
- the end of gestation or point at which birth is imminent; "a healthy baby born at full term" (同)full term
- a limited period of time; "a prison term"; "he left school before the end of term"
- a word or expression used for some particular thing; "he learned many medical terms"
- any distinct quantity contained in a polynomial; "the general term of an algebraic equation of the n-th degree"
- one of the substantive phrases in a logical proposition; "the major term of a syllogism must occur twice"
- a concavity in a surface produced by pressing; "he left the impression of his fingers in the soft mud" (同)impression, imprint
- a long-term economic state characterized by unemployment and low prices and low levels of trade and investment (同)slump, economic crisis
- a mental state characterized by a pessimistic sense of inadequacy and a despondent lack of activity
- angular distance below the horizon (especially of a celestial object)
- pushing down; "depression of the space bar on the typewriter"
- sad feelings of gloom and inadequacy
- prolonged unfulfilled desire or need (同)yearning, hungriness
- (neuroscience) of or involving synapses
PrepTutorEJDIC
- (距離・物の長さが)『長い』 / (時間が)『長い』,長く続く / 《時間・距離などを表離などを表す語を伴って》長さが…の / 『長々しい』,あきあきする / (数量が標準よりも)『多い』,長い / (人が)やせてひょろ長い / 長く,長い間,久しく / …じゅう / ずっと(前に,後に) / 長い間
- 『熱望する』
- 〈C〉『専門用語』,術語 / 〈C〉(一般に)語[句],言葉 / 《複数形で》言い道,言飯遣い / 〈C〉『期間』 / 〈C〉〈U〉『学期』 / 《複数形で》(人との)間柄,仲《+with+名》 / 《複数形で》(協定などの)『条件』;要求額,値段 / 〈C〉(数式で)項 / 《term+名〈目〉+名(形)〈補〉》(…と)…‘を'名づける,呼ぶ
- 〈C〉『くぼ地』,くぼみ / 〈U〉〈C〉『意気消沈』,憂うつ;うつ病 / 〈C〉『不景気』,不況 / 〈U〉押し下げること,降下,低下
- 『あこがれ』,熱望 / (目の表情などが)あこがれの,熱望している
UpToDate Contents
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- 1. うつ病のスクリーニング screening for depression
- 2. Unipolar depression in adults: Course of illness
- 3. 成人における単極性うつ病：重度の難治性（再発性）うつ病のマネージメント unipolar depression in adults management of highly resistant refractory depression
- 4. 成人における単極性うつ病：経頭蓋磁気刺激（TMS）による治療 unipolar depression in adults treatment with transcranial magnetic stimulation tms
- 5. 成人における単極性うつ病：難治性うつ病の治療 unipolar depression in adults treatment of resistant depression
English Journal
- The change of spatial cognition ability in depression rat model and the possible association with down-regulated protein expression of TRPC6.
- Liu Y1, Liu C2, Qin X2, Zhu M2, Yang Z3.
- Behavioural brain research.Behav Brain Res.2015 Nov 1;294:186-93. doi: 10.1016/j.bbr.2015.07.062. Epub 2015 Aug 3.
- An increasing number of researches have focused on the cognitive changes in depression patients. Here, we observed impaired cognitive ability in a rat depression model along with down-regulated expression of canonical transient receptor potential 6 (TRPC6) protein. The cognitive defect could be resc
- PMID 26248296
- Rapastinel (GLYX-13) has therapeutic potential for the treatment of post-traumatic stress disorder: Characterization of a NMDA receptor-mediated metaplasticity process in the medial prefrontal cortex of rats.
- Burgdorf J1, Kroes RA2, Zhang XL3, Gross AL2, Schmidt M2, Weiss C4, Disterhoft JF4, Burch RM2, Stanton PK3, Moskal JR5.
- Behavioural brain research.Behav Brain Res.2015 Nov 1;294:177-85. doi: 10.1016/j.bbr.2015.07.039. Epub 2015 Jul 22.
- Rapastinel (GLYX-13) is a NMDA receptor modulator with glycine-site partial agonist properties. It is a robust cognitive enhancer and shows rapid and long-lasting antidepressant properties in both animal models and in humans. Contextual fear extinction (CFE) in rodents has been well characterized an
- PMID 26210936
- Fructose consumption reduces hippocampal synaptic plasticity underlying cognitive performance.
- Cisternas P1, Salazar P1, Serrano FG1, Montecinos-Oliva C1, Arredondo SB2, Varela-Nallar L2, Barja S3, Vio CP1, Gomez-Pinilla F4, Inestrosa NC5.
- Biochimica et biophysica acta.Biochim Biophys Acta.2015 Nov;1852(11):2379-90. doi: 10.1016/j.bbadis.2015.08.016. Epub 2015 Aug 21.
- Metabolic syndrome (MetS) is a global epidemic, which involves a spectrum of metabolic disorders comprising diabetes and obesity. The impact of MetS on the brain is becoming to be a concern, however, the poor understanding of mechanisms involved has limited the development of therapeutic strategies.
- PMID 26300486
Japanese Journal
- 長期抑圧の調節によるリカレントネットワークに生じる距離に依存する結合強度分布と指向性興奮伝播への影響 (ニューロコンピューティング)
- 佐村 俊和,杉崎 えり子,酒井 裕 [他]
- 電子情報通信学会技術研究報告 : 信学技報 112(227), 73-78, 2012-10-04
- NAID 40019481429
- 前庭動眼反射と視運動性眼球運動の適応への小脳シナプス可塑性の関与
- 平野 丈夫
- Equilibrium research 70(2), 104-109, 2011-04-01
- … The floccular region of the cerebellar cortex regulates the amplitude and timing of these reflexes through the inhibitory synaptic outputs of Purkinje neurons. … Long-term depression (LTD), a type of plasticity at the synapses between parallel fibers and a Purkinje cell, in the flocculus, has been proposed to contribute to the adaptation of VOR and OKR. …
- NAID 10029512343
- 海馬が合成する神経ステロイドの記憶学習モジュレーション
- 川戸 佳
- 生物物理 51(2), 076-079, 2011-03-25
- … Hippocampal sex-steroids modulate memory-related synaptic plasticity not only slowly but also rapidly. … The long-term depression is modulated rapidly by changes of E2 level. … Hippocampus-derived sex-steroids play a major role in modulation of synaptic plasticity. …
- NAID 10028105804
Related Links
- Definition of long-term synaptic depression in the Definitions.net dictionary. Meaning of long-term synaptic depression. What does long-term synaptic depression mean? Information and translations of long-term synaptic depression in ...
- Publication » Stress and long-term synaptic depression. Article Stress and long-term synaptic depression M J Rowan R Anwyl Lin Xu Department of Pharmacology and Therapeutics, Trinity College Dublin, Dublin, Leinster ...
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★リンクテーブル★
| リンク元 | 「シナプス長期抑圧」 |
| 関連記事 | 「depression」「term」「long」「synaptic」「long term」 |
「シナプス長期抑圧」
「depression」
- n.
「term」
- n.
- 期間、用語
- v.
- 名付ける
「long」
「synaptic」
- シナプスの、シナプス性の