WordNet

primarily temporal sense; being or indicating a relatively great or greater than average duration or passage of time or a duration as specified; "a long life"; "a long boring speech"; "a long time"; "a long friendship"; "a long game"; "long ago"; "an hour long"
(of speech sounds or syllables) of relatively long duration; "the English vowel sounds in `bate, `beat, `bite, `boat, `boot are long"
for an extended distance
for an extended time or at a distant time; "a promotion long overdue"; "something long hoped for"; "his name has long been forgotten"; "talked all night long"; "how long will you be gone?"; "arrived long before he was expected"; "it is long after your bedtime"
having or being more than normal or necessary:"long on brains"; "in long supply"
holding securities or commodities in expectation of a rise in prices; "is long on coffee"; "a long position in gold"
involving substantial risk; "long odds"
of relatively great height; "a race of long gaunt men"- Sherwood Anderson; "looked out the long French windows"
primarily spatial sense; of relatively great or greater than average spatial extension or extension as specified; "a long road"; "a long distance"; "contained many long words"; "ten miles long"
fasten or secure with chains; "Chain the chairs together"
a unit of length
a necklace made by a stringing objects together; "a string of beads"; "a strand of pearls"; (同)string, strand
a linked or connected series of objects; "a chain of daisies"
a series of (usually metal) rings or links fitted into one another to make a flexible ligament
anything that acts as a restraint
(chemistry) a series of linked atoms (generally in an organic molecule) (同)chemical chain
a series of things depending on each other as if linked together; "the chain of command"; "a complicated concatenation of circumstances" (同)concatenation
(business) a number of similar establishments (stores or restaurants or banks or hotels or theaters) under one ownership
connect or arrange into a chain by linking
the 3rd letter of the Roman alphabet (同)c
(music) the keynote of the scale of C major
a general-purpose programing language closely associated with the UNIX operating system
prolonged unfulfilled desire or need (同)yearning, hungriness

PrepTutorEJDIC

(距離・物の長さが)『長い』 / (時間が)『長い』,長く続く / 《時間・距離などを表離などを表す語を伴って》長さが…の / 『長々しい』,あきあきする / (数量が標準よりも)『多い』,長い / (人が)やせてひょろ長い / 長く,長い間,久しく / …じゅう / ずっと(前に,後に) / 長い間
『熱望する』
『鎖』;(装飾用の)鎖 / 《複数形で》『束縛』,拘束;囚人をつなぐ鎖 / (物事の)『連続』,つながり《+『of』+『名』》 / (商店・銀行・ホテルなどの)チェーン(一連の店が同一資本のもとで連携して経営される方式;その店) / チェーン(測量で用いられる単位;約21.7m) / …'を'『鎖でつなぐ』《+『up』(『together』)+『名,』+『名』+『up』(『together』)》
〈U〉〈C〉(…の)(量・額などの)不足,欠乏《+『of』(『in』)+『名』》 / 〈C〉不足分,不足量,不足額 / 〈C〉(精神・肉体などの)欠陥
carbonの化学記号
『あこがれ』,熱望 / (目の表情などが)あこがれの,熱望している

UpToDate Contents

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1. 妊娠時の急性脂肪肝 acute fatty liver of pregnancy
2. HELLP症候群 hellp syndrome
3. 妊娠中に発現した肝疾患に対するアプローチ approach to liver disease occurring during pregnancy

English Journal

Characterization of Chorioretinopathy Associated with Mitochondrial Trifunctional Protein Disorders: Long-Term Follow-up of 21 Cases.

Boese EA1, Jain N2, Jia Y1, Schlechter CL1, Harding CO3, Gao SS1, Patel RC1, Huang D1, Weleber RG1, Gillingham MB3, Pennesi ME4.
Ophthalmology.Ophthalmology.2016 Oct;123(10):2183-95. doi: 10.1016/j.ophtha.2016.06.048. Epub 2016 Aug 2.
PURPOSE: To assess long-term effects of genotype on chorioretinopathy severity in patients with mitochondrial trifunctional protein (MTP) disorders.DESIGN: Retrospective case series.PARTICIPANTS: Consecutive patients with MTP disorders evaluated at a single center from 1994 through 2015, including 1
PMID 27491397

Early dietary therapy for long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency can maintain vision despite subnormal retinal function.

Kivelä TT1.
Acta paediatrica (Oslo, Norway : 1992).Acta Paediatr.2016 Sep 17. doi: 10.1111/apa.13595. [Epub ahead of print]
What is special about long-chain fatty acids and the retina Nobody knows exactly, but these two do not always mix well, as a failure to oxidise this particular class of fatty acids properly is the only mitochondrial β-oxidation defect that leads to chorioretinopathy (1). Its most common cause is a
PMID 27639177

Most patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency develop pathological or subnormal retinal function.

Fahnehjelm KT1,2,3, Liu Y4,5, Olsson D6,7, Amrén U8,9, Haglind CB6,7, Holmström G10, Halldin M11, Andreasson S12, Nordenström A6,7.
Acta paediatrica (Oslo, Norway : 1992).Acta Paediatr.2016 Jul 27. doi: 10.1111/apa.13536. [Epub ahead of print]
AIM: There have been few studies on long-term electroretinographic findings in patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD). This study correlated long-term electroretinographic findings with age, metabolic control and clinical symptoms.METHODS: We examined 12 Swedish
PMID 27461099