同: LOH

WordNet

relating to or applicable to or concerned with the administration of a city or town or district rather than a larger area; "local taxes"; "local authorities"
public transport consisting of a bus or train that stops at all stations or stops; "the local seemed to take forever to get to New York"
affecting only a restricted part or area of the body; "local anesthesia"
of or belonging to or characteristic of a particular locality or neighborhood; "local customs"; "local schools"; "the local citizens"; "a local point of view"; "local outbreaks of flu"; "a local bus line"
the presence of abnormally high levels of calcium in the blood; usually the result of excessive bone resorption in hyperparathyroidism or Pagets disease (同)hypercalcaemia

PrepTutorEJDIC

『一地方の』,ある土地の,(特に)自分の住んでいる土地の;地方に特有な / (全体からみて)『部分的な』,局部の,狭い部分の / 《米》各駅停車の / 《話》《しばしば複数形で》その土地に住んでいる人々 / 《米話》(新聞の)地方記事 / 《話》(各駅停車の)列車,電車,バス / 《米》(労働組合などの)支部
低カロリーの

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1. 悪性腫瘍の高カルシウム血症 hypercalcemia of malignancy
2. 高カルシウム血症の原因 etiology of hypercalcemia
3. 高カルシウム血症の治療 treatment of hypercalcemia
4. 骨転移を有する成人患者の疫学、臨床所見、診断、およびマネージメントの概要 overview of the epidemiology clinical presentation diagnosis and management of adult patients with bone metastasis
5. 多発性骨髄腫の合併症の治療 treatment of the complications of multiple myeloma

English Journal

[Treatment of malignancy associated hypercalcemia].

Tai N1, Inoue D.
Clinical calcium.Clin Calcium.2014 Aug;24(8):1223-8. doi: CliCa140812231228.
Malignancy associated hypercalcemia (MAH) is a paraneoplastic syndrome that impairs the quality of life and that can be a direct cause of death. MAH is classified into two major categories : humoral hypercalcemia of malignancy (HHM) and local osteolytic hypercalcemia (LOH) . Bisphosphonates are the
PMID 25065875

[The significance of early diagnosis of cancer-related hypercalcaemia].

Radványi I1, Csikós A, Balogh S.
Orvosi hetilap.Orv Hetil.2013 Sep 1;154(35):1367-73. doi: 10.1556/OH.2013.29665.
in

English, HungarianA tumorasszociált hypercalcaemia az egyik leggyakrabban előforduló, életet veszélyeztető anyagcsere-rendellenesség daganatos betegekben, amelynek prevalenciája 20–30% a tumor típusától függően. Két fő formája a humorális és a lokális osteolyticus hyperca

PMID 23974972

A case of myeloma with hypercalcemia caused by high serum concentrations of both parathyroid hormone-related peptide (PTHrP) and macrophage inflammatory protein-1α (MIP-1α).

Shimizu H1, Monden T, Tomotsune T, Nakatani Y, Domeki N, Matsumura M, Jojima T, Kawagoe Y, Kasai K.
Internal medicine (Tokyo, Japan).Intern Med.2011;50(24):2993-6. Epub 2011 Dec 15.
A 62-year-old woman was admitted with dry mouth, general fatigue, and severe back pain. Biochemistry examination showed extreme hypercalcemia (21.2 mg/dL). Bone marrow examination was negative, but needle biopsy of a metastatic lung tumor revealed abnormal plasma cells; thus, multiple myeloma stage
PMID 22185991

Japanese Journal

当院における高カルシウム血症の病因・病態の解析と治療 : 高カルシウム血症クリーゼも含めて

作田亜有子,飯嶋寿江,百目木希実,鈴木國弘,加瀬浩之,川越宣明,笠井貴久男
Dokkyo journal of medical sciences 39(1), 45-55, 2012-03-25
… 示していた.三次性副甲状腺機能亢進症10 例の内3 例は,副甲状腺摘出,自家移植を受けた.腫瘍随伴性高Ca 血症6 例の内PTH-related protein(PTHrP)高値を示すhumoral hypercalcemia of malignancy(HHM)が4 例,local osteolytic hypercalcemia (LOH)が1 例及び両機序による混合型1 例であった.VitD/Ca 過量投与は薬剤中止あるいは減量投与により軽快し,バセドウ病は甲状腺ホルモン低下に伴い正常化 …
NAID 110009005164

A Case of Myeloma with Hypercalcemia Caused by High Serum Concentrations of both Parathyroid Hormone-related Peptide (PTHrP) and Macrophage Inflammatory Protein-1.ALPHA. (MIP-1.ALPHA.)

Shimizu Hiroaki,Monden Tsuyoshi,Tomotsune Takanori,Nakatani Yuki,Domeki Nozomi,Matsumura Mihoko,Jojima Teruo,Kawagoe Yoshiaki,Kasai Kikuo
Internal Medicine 50(24), 2993-2996, 2011
… Biochemistry examination showed extreme hypercalcemia (21.2 mg/dL). … Her myeloma appeared to have simultaneously caused two mechanisms producing hypercalcemia: humoral hypercalcemia of malignancy (HHM) by PTHrP and local osteolytic hypercalcemia (LOH) by MIP-1α. … Therefore, the combination of two calcium-modulating abnormalities likely aggravated her hypercalcemia. …
NAID 130002062724

A case of esophageal small cell carcinoma associated with hypercalcemia causing severe acute pancreatitis

菅野香,引地拓人,斎藤桂悦,渡辺研也,高木忠之,渋川悟朗,若槻尊,今村秀道,高橋裕太,佐藤愛,佐藤匡記,入澤篤志,小原勝敏,大平弘正
Fukushima journal of medical science 53(1), 51-60, 2007-06-01
… Abdominal pain, marked hypercalcemia and hyperamylasemia were noted and the patient was diagnosed with severe acute pancreatitis. … Because the level of blood parathyroid hormone-related protein was elevated, we considered that esophageal small cell carcinoma caused human hypercalcemia of malignancy and that metastatic bone tumors caused local osteolytic hypercalcemia, eventually leading to severe acute pancreatitis. …
NAID 10026160190