WordNet
- pursue a positive and satisfying existence; "You must accept yourself and others if you really want to live"
- actually being performed at the time of hearing or viewing; "a live television program"; "brought to you live from Lincoln Center"; "live entertainment involves performers actually in the physical presence of a live audience" (同)unrecorded
- abounding with life and energy; "the club members are a really live bunch"
- charged with an explosive; "live ammunition"; "a live bomb"
- exerting force or containing energy; "live coals"; "tossed a live cigarette out the window"; "got a shock from a live wire"; "live ore is unmined ore"; "a live bomb"; "a live ball is one in play"
- highly reverberant; "a live concert hall"
- in current use or ready for use; "live copy is ready to be set in type or already set but not yet proofread"
- lead a certain kind of life; live in a certain style; "we had to live frugally after the war"
- not recorded; "the opera was broadcast live"
- of current relevance; "a live issue"; "still a live option"
- a person who has a special life style; "a high liver"
- large and complicated reddish-brown glandular organ located in the upper right portion of the abdominal cavity; secretes bile and functions in metabolism of protein and carbohydrate and fat; synthesizes substances involved in the clotting of the blood; sy
- liver of an animal used as meat
- someone who lives in a place; "a liver in cities"
- a tiny granule in the cytoplasm that is where protein synthesis takes place under the direction of mRNA
PrepTutorEJDIC
- 『生きている』,生命がある / 《副詞[句]を伴って》〈人などが〉『生き続ける』 / 〈物事が〉長く続く,存続する / 《場所を表す副詞[句]を伴って》〈人などが〉『住む』,居住する / 《副詞[句]を伴って》『生活する』,暮らす / 生人を楽しむ,おもしろく桟らす / 《a+形容詞癌lifeを目的語にして》〈…を生活〉‘を'する / 〈思想など〉‘を'実銭する
- 《名詞の前にのみ用いて》『生きている』 / 『活気のある』 / (問題などが)当面の / 燃えている / (弾丸などが)まだ爆発してない,未発の / まだ動いている(働いている),有効な / 電流が通じている / (放走が)生の,実況の
- (ある態度で)生活する人;居住者
- 〈C〉『肝臓』 / 〈U〉(食用にする)動物の肝臓,レバー
UpToDate Contents
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English Journal
- The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C19*35 and CYP2C19*2 Alleles.
- Chaudhry AS1, Prasad B1, Shirasaka Y1, Fohner A1, Finkelstein D1, Fan Y1, Wang S1, Wu G1, Aklillu E1, Sim SC1, Thummel KE1, Schuetz EG2.
- Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2015 Aug;43(8):1226-35. doi: 10.1124/dmd.115.064428. Epub 2015 May 28.
- CYP2C19 rs12769205 alters an intron 2 branch point adenine leading to an alternative mRNA in human liver with complete inclusion of intron 2 (exon 2B). rs12769205 changes the mRNA reading frame, introduces 87 amino acids, and leads to a premature stop codon. The 1000 Genomes project (http://browser.
- PMID 26021325
- Development of Murine Cyp3a Knockout Chimeric Mice with Humanized Liver.
- Kato K1, Ohbuchi M1, Hamamura S1, Ohshita H1, Kazuki Y1, Oshimura M1, Sato K1, Nakada N1, Kawamura A1, Usui T1, Kamimura H1, Tateno C2.
- Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2015 Aug;43(8):1208-17. doi: 10.1124/dmd.115.063479. Epub 2015 May 15.
- We DEVELOPED MURINE CYP3A KNOCKOUT KO CHIMERIC MICE WITH HUMANIZED LIVER EXPRESSING HUMAN P450S SIMILAR TO THOSE IN HUMANS AND WHOSE LIVERS AND SMALL INTESTINES DO NOT EXPRESS MURINE CYP3A THIS: approach may overcome effects of residual mouse metabolic enzymes like Cyp3a in conventional chimeric mic
- PMID 25979261
- Characterization of Species Differences in Tissue Diltiazem Deacetylation Identifies Ces2a as a Rat-Specific Diltiazem Deacetylase.
- Kurokawa T1, Fukami T2, Nakajima M1.
- Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2015 Aug;43(8):1218-25. doi: 10.1124/dmd.115.064089. Epub 2015 May 15.
- Diltiazem, a calcium channel blocker, is mainly metabolized via demethylation or deacetylation in humans. Diltiazem demethylation is catalyzed by cytochrome P450 2D6 and 3A4. Although it was previously reported that the area under the curve ratio of deacetyldiltiazem to diltiazem after oral dosing w
- PMID 25979260
Japanese Journal
- In Vitro Enhancement of Carvedilol Glucuronidation by Amiodarone-Mediated Altered Protein Binding in Incubation Mixture of Human Liver Microsomes with Bovine Serum Albumin
- Estimating the Differences of UGT1A1 Activity in Recombinant UGT1A1 Enzyme, Human Liver Microsomes and Rat Liver Microsome Incubation Systems <i>in Vitro</i>
- Inhibitory Potential of Twenty Five Anti-tuberculosis Drugs on CYP Activities in Human Liver Microsomes
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- [liv]
- [laiv]
- 同
- LAIV
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肝臓