liposarcoma

出典: meddic

脂肪肉腫

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「sarcoma of fat cells」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/04/19 18:14:04」(JST)

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英文文献

  • Patterns of TPD52 overexpression in multiple human solid tumor types analyzed by quantitative PCR.
  • Tennstedt P1, Bölch C2, Strobel G2, Minner S2, Burkhardt L2, Grob T2, Masser S2, Sauter G2, Schlomm T1, Simon R2.Author information 1Martini-Clinic, Section for Translational Prostate Cancer Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.2Institute of Pathology, Section for Translational Prostate Cancer Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.AbstractTumor protein D52 (TPD52) is located at chromosome 8q21, a region that is frequently gained or amplified in multiple human cancer types. TPD52 has been suggested as a potential target for new anticancer therapies. In order to analyze TPD52 expression in the most prevalent human cancer types, we employed quantitative PCR to measure TPD52 mRNA levels in formalin-fixed tissue samples from more than 900 cancer tissues obtained from 29 different human cancer types. TPD52 was expressed at varying levels in all tested normal tissues, including skin, lymph node, lung, oral mucosa, breast, endometrium, ovary, vulva, myometrium, liver, pancreas, stomach, kidney, prostate, testis, urinary bladder, thyroid gland, brain, muscle and fat tissue. TPD52 was upregulated in 18/29 (62%) tested cancer types. Strongest expression was found in non-seminoma (56-fold overexpression compared to corresponding normal tissue), seminoma (42-fold), ductal (28-fold) and lobular breast cancer (14-fold). In these tumor types, TPD52 upregulation was found in the vast majority (>80%) of tested samples. Downregulation was found in 11 (38%) tumor types, most strongly in papillary renal cell cancer (-8-fold), leiomyosarcoma (-6-fold), clear cell renal cell cancer (-5-fold), liposarcoma (-5-fold) and lung cancer (-4-fold). These results demonstrate that TPD52 is frequently and strongly upregulated in many human cancer types, which may represent candidate tumor types for potential anti-TPD52 therapies.
  • International journal of oncology.Int J Oncol.2014 Feb;44(2):609-15. doi: 10.3892/ijo.2013.2200. Epub 2013 Nov 29.
  • Tumor protein D52 (TPD52) is located at chromosome 8q21, a region that is frequently gained or amplified in multiple human cancer types. TPD52 has been suggested as a potential target for new anticancer therapies. In order to analyze TPD52 expression in the most prevalent human cancer types, we empl
  • PMID 24317684
  • Myxoid liposarcoma of the spermatic cord: US and MR imaging findings.
  • Abete L, Simonato A, Toncini C, Carmignani G, Derchi LE.Author information Dipartimento Scienze Chirurgiche, Settore Anatomia Patologica, Università di Genova, Genova, Italy.AbstractWe report a patient with myxoid liposarcoma of the spermatic cord in whom combined use of both ultrasound (US) and MRI helped to suggest the diagnosis. The lesion was solid at US and vascularized at color Doppler. T1-weighted MRI did not show fat within it; on T2-weighted images it had high signal intensity, with a cyst-like appearance. It is known that fat-poor myxoid liposarcomas with high water content may mimic a cystic lesion on non-contrast-enhanced MR; then, a combination of MRI findings, suggesting a cyst, and of US findings, showing the mass was actually solid and vascularized, allowed preoperatively the diagnosis of fat-poor myxoid liposarcoma. © 2013 Wiley Periodicals, Inc. J Clin Ultrasound 42:96-99, 2014.
  • Journal of clinical ultrasound : JCU.J Clin Ultrasound.2014 Feb;42(2):96-9. doi: 10.1002/jcu.22068. Epub 2013 Jul 17.
  • We report a patient with myxoid liposarcoma of the spermatic cord in whom combined use of both ultrasound (US) and MRI helped to suggest the diagnosis. The lesion was solid at US and vascularized at color Doppler. T1-weighted MRI did not show fat within it; on T2-weighted images it had high signal i
  • PMID 23861011
  • Challenging epithelioid mesenchymal neoplasms: mimics and traps.
  • Cacciatore M, Dei Tos AP.Author information Departments of Oncology and Pathology, Treviso, Italy.AbstractSUMMARY: Epithelioid mesenchymal malignancies represent a major diagnostic challenge. Epithelioid morphology can be observed in a variety of soft tissue neoplasms, however there exist specific subtypes in which an epithelioid apperance constitutes the most distinctive morphological feature. Moving from epithelioid sarcoma of Enzinger (the prototype of sarcoma with epithelioid morphology), this review will focus on the most relevant entities: namely epithelioid haemangioendothelioma and angiosarcoma, pseudomyogenic haemangioendothelioma, epithelioid malignant peripheral nerve sheath tumour, epithelioid sclerosing fibrosarcoma, epithelioid pleomorphic liposarcoma, alveolar soft part sarcoma, and undifferentiated soft tissue sarcoma with epithelioid morphology. Differential diagnoses and major pitfalls will be discussed in detail.
  • Pathology.Pathology.2014 Feb;46(2):126-34. doi: 10.1097/PAT.0000000000000063.
  • SUMMARY: Epithelioid mesenchymal malignancies represent a major diagnostic challenge. Epithelioid morphology can be observed in a variety of soft tissue neoplasms, however there exist specific subtypes in which an epithelioid apperance constitutes the most distinctive morphological feature. Moving f
  • PMID 24384587

和文文献

  • 症例 Bochdalek孔ヘルニアと鑑別を要した横隔膜脂肪腫の1例
  • 直海 晃,親松 裕典,成田 久仁夫 [他]
  • 胸部外科 = The Japanese journal of thoracic surgery 67(10), 942-945, 2014-09
  • NAID 40020188581
  • 脂肪芽細胞 : 形態学的特徴と診断学的価値
  • 久岡 正典
  • 産業医科大学雑誌 36(2), 115-121, 2014-06-01
  • 脂肪芽細胞は概念的に脂肪細胞の前駆的細胞ないし未成熟な細胞であり,組織学的には脂質を含んだ単ないし多空胞状の細胞質と陥凹し,しばしば帆立貝様の濃染性核を持つことを特徴とする.主として腫瘍性疾患において見られるが,前脂肪細胞のように正常脂肪組織の分化過程をある程度再現する細胞とみなされている.伝統的にその存在は特に脂肪肉腫の診断において強調されてきたが,Lochkern細胞や褐色脂肪,偽脂肪芽細胞な …
  • NAID 110009823330
  • 急速に増大した後腹膜脂肪肉腫の1例
  • 井出 健弘,柳原 豊,浅井 聖史 [他]
  • 西日本泌尿器科 = The Nishinihon journal of urology 76(4), 132-136, 2014-04
  • NAID 40020042077

関連リンク

著者 角田 洋一 川村 憲彦 福原 慎一郎 出版者 泌尿器科紀要刊行会 刊行物名 泌尿器科紀要54巻2号147-150p ISSN:00181994 被引用文献数 1 所属 角田 洋一 川村 憲彦 福原 慎一郎 抄録 症例1(69歳男性)。左鼠径部腫脹を主訴 ...
Lipoma, myxoid liposarcoma and retroperitoneal liposarcoma are explained for patients and practitioners, with patient stories and support group listings. ... Liposarcoma is a rare cancer of connective tissues that resemble fat cells ...

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★リンクテーブル★
リンク元脂肪肉腫
拡張検索dedifferentiated liposarcoma

脂肪肉腫」

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liposarcoma
脂肪形成肉腫 lipoplastic sarcoma



dedifferentiated liposarcoma」

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脱分化型脂肪肉腫

liposarcoma




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