WordNet

the 24th letter of the Roman alphabet (同)x, ex
a conjugated protein having a lipid component; the principal means for transporting lipids in the blood

PrepTutorEJDIC

Christ / Christian
x-axis

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1. 原発性胆汁性肝硬変における高コレステロール血症およびアテローム性動脈硬化症 hypercholesterolemia and atherosclerosis in primary biliary cirrhosis
2. 脂質異常症の二次的原因 secondary causes of dyslipidemia
3. 血中脂質およびリポ蛋白の測定 measurement of blood lipids and lipoproteins
4. 原発性胆汁性肝硬変の臨床症状、診断、および自然経過 clinical manifestations diagnosis and natural history of primary biliary cirrhosis
5. 早産児における非経口栄養 parenteral nutrition in premature infants

English Journal

Lipoprotein X Detected in a Case of Hypercholesterolemia Associated With Chronic Cholangiohepatitis.

Ha J1, Lee SG2, Kim JH1.
Annals of laboratory medicine.Ann Lab Med.2017 Nov;37(6):550-552. doi: 10.3343/alm.2017.37.6.550.
PMID 28840998

A novel homozygous mutation causing lecithin-cholesterol acyltransferase deficiency in a proband of Romanian origin with a record of extreme gestational hyperlipidemia.

Rial-Crestelo D1, Santos-Recuero I2, Julve J3, Blanco-Vaca F3, Torralba M4.
Journal of clinical lipidology.J Clin Lipidol.2017 Aug 24. pii: S1933-2874(17)30413-0. doi: 10.1016/j.jacl.2017.08.008. [Epub ahead of print]
PMID 28942093

Lipoprotein-X disease in the setting of severe cholestatic hepatobiliary autoimmune disease.

Heinl RE1, Tennant HM2, Ricketts JC1, Rice CR3, Robinson CB3, Sandesara PB4, Moriarty PM2, Sperling L5.
Journal of clinical lipidology.J Clin Lipidol.2017 Jan - Feb;11(1):282-286. doi: 10.1016/j.jacl.2016.09.016. Epub 2016 Oct 4.
PMID 28391896

Japanese Journal

Low-Density Lipoprotein Cholesterol Goal Attainment Rates by Initial Statin Monotherapy Among Patients With Dyslipidemia and High Cardiovascular Risk in Japan : A Retrospective Database Analysis

Circulation journal : official journal of the Japanese Circulation Society 82(6), 1605-1613, 2018-06
NAID 40021555203

Polydatin Improves Glucose and Lipid Metabolisms in Insulin-Resistant HepG2 Cells through the AMPK Pathway

Biological & pharmaceutical bulletin 41(6), 891-898, 2018-06
NAID 40021553781

Upregulation of lipoprotein receptors on brain endothelial cells and neurons in the early phase of ischemic stroke in mice

Journal of Medical and Dental Sciences 65(2), 59-71, 2018-06
NAID 120006486736

「リポ蛋白X」

　　[★]

英: lipoprotein X, LpX, lipoprotein-X
関: リポ蛋白質

[show details]

リポ蛋白質X : 13 件
リポ蛋白X : 87 件
リポタンパク質X : 10 件
リポタンパクX : 34 件

胆汁うっ滞をきたす病態において血漿中に増加が見られる異常リポ蛋白。

参考

1. lipoprotein-X electrophoresis

http://www.nature.com/ki/journal/v60/n2/fig_tab/4492450f1.html

2. Lipoprotein-X and LCAT Deficiency Thomas Dayspring MD, FACP

http://www.lipidcenter.com/pdf/LipoproteinX.pdf

3. wiki en

http://en.wikipedia.org/wiki/Lipoprotein-X

4. Lipoprotein-X.

Narayanan S.AbstractLipoprotein-X is an abnormal lipoprotein that appears in the sera of patients with obstructive jaundice, and thus is a sensitive indicator of cholestasis. In patients with familial plasma lecithin, Cholesterol acyltransferase (LCAT) deficiency, there is an inverse relationship between plasma Lp-X levels and LCAT activity. Ultracentrifugation procedures utilized for isolation of Lp-X have shown that it is associated with the low density lipoprotein fraction. Lp-X can be visualized by electrophoresis on either Agar or Agarose. The purity of Lp-X preparations has been documented by immunochemical procedures. The availability of highly purified antisera to Lp-X has served as a basis of one of the assay procedures for this lipoprotein. It's chemical composition has been established. Phospholipids and unesterified cholesterol constitute the bulk of the Lp-X molecule. Electron microscopic studies have demonstrated that Lp-X is a spherical particle which has strong aggregating properties. Membrane bound enzymes have been shown to aggregate with Lp-X. The fact that bile lipoprotein can be converted to Lp-X by the addition of albumin and that Lp-X can be converted to bile lipoprotein by the addition of bile salts offers a possible explanation for the origins of Lp-X. Phospholipases of plasma might play a role in the catabolism of Lp-X. The value and limitations of Lp-X determinations will also be addressed in this review.
CRC critical reviews in clinical laboratory sciences.CRC Crit Rev Clin Lab Sci.1979 Aug;11(1):31-51.
Lipoprotein-X is an abnormal lipoprotein that appears in the sera of patients with obstructive jaundice, and thus is a sensitive indicator of cholestasis. In patients with familial plasma lecithin, Cholesterol acyltransferase (LCAT) deficiency, there is an inverse relationship between plasma Lp-X le
PMID 389551