lipid-derived autacoids

出典: meddic

Eicosanoid(s) ; Platelet-activat- ing factor
Eicosanoid(s) ; Platelet-activat- ing factor
Eicosanoid(s) ; Platelet-activat- ing factor

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  • Multidrug resistance protein 1 (MRP1, ABCC1), a "multitasking" ATP-binding cassette (ABC) transporter.
  • Cole SP1.
  • The Journal of biological chemistry.J Biol Chem.2014 Nov 7;289(45):30880-8. doi: 10.1074/jbc.R114.609248. Epub 2014 Oct 3.
  • The multidrug resistance protein 1 (MRP1) encoded by ABCC1 was originally discovered as a cause of multidrug resistance in tumor cells. However, it is now clear that MRP1 serves a broader role than simply mediating the ATP-dependent efflux of drugs from cells. The antioxidant GSH and the pro-inflamm
  • PMID 25281745
  • Satiety factor oleoylethanolamide recruits the brain histaminergic system to inhibit food intake.
  • Provensi G1, Coccurello R2, Umehara H1, Munari L1, Giacovazzo G2, Galeotti N1, Nosi D3, Gaetani S4, Romano A4, Moles A2, Blandina P1, Passani MB5.
  • Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2014 Aug 5;111(31):11527-32. doi: 10.1073/pnas.1322016111. Epub 2014 Jul 21.
  • Key factors driving eating behavior are hunger and satiety, which are controlled by a complex interplay of central neurotransmitter systems and peripheral stimuli. The lipid-derived messenger oleoylethanolamide (OEA) is released by enterocytes in response to fat intake and indirectly signals satiety
  • PMID 25049422
  • Prostaglandin E2 alters Wnt-dependent migration and proliferation in neuroectodermal stem cells: implications for autism spectrum disorders.
  • Wong CT, Ahmad E, Li H, Crawford DA1.
  • Cell communication and signaling : CCS.Cell Commun Signal.2014 Mar 23;12:19. doi: 10.1186/1478-811X-12-19.
  • Prostaglandin E2 (PGE2) is a natural lipid-derived molecule that is involved in important physiological functions. Abnormal PGE2 signalling has been associated with pathologies of the nervous system. Previous studies provide evidence for the interaction of PGE2 and canonical Wnt signalling pathways
  • PMID 24656144


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  • vt.
  • 由来する

bornecome fromdescenddraweduceelicitstem

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「obtain; "derive pleasure from one''s garden"」

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「develop or evolve from a latent or potential state」

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「come from; "The present name derives from an older form"」

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「《『derive』+『名』+『from』+『名』(do『ing』)》(…から)…‘を'『引き出す』,得る,求める / 《『derive from』+『名』(do『ing』)》《文》(…から)派生する,(…に)由来する」

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「come from; be connected by a relationship of blood, for example; "She was descended from an old Italian noble family"; "he comes from humble origins"」
come, descend



  • n.

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「(botany) either of the two parts of a bilabiate corolla or calyx」

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「either the outer margin or the inner margin of the aperture of a gastropod''s shell」

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「either of two fleshy folds of tissue that surround the mouth and play a role in speaking」

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「〈C〉『くちびる』,口もと / 《複数形で》(発音器官としての)くちびる,口 / 〈U〉《俗》生意気な言葉 / 〈C〉(容器などの)口,へり,縁;(峡谷・火山などの)口 / 〈C〉(植物の)唇弁(しんべん)」


  [★] 脂質

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「an oily organic compound insoluble in water but soluble in organic solvents; essential structural component of living cells (along with proteins and carbohydrates)」
lipide, lipoid

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「formed or developed from something else; not original; "the belief that classes and organizations are secondary and derived"- John Dewey」


  [★] オータコイド

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「any physiologically active internal secretion especially one of uncertain classification」