WordNet
- capable of being influenced or formed; "the plastic minds of children"; "a pliant nature" (同)pliant
- generic name for certain synthetic or semisynthetic materials that can be molded or extruded into objects or films or filaments or used for making e.g. coatings and adhesives
PrepTutorEJDIC
- 〈U〉『寂ラスチック』;〈C〉プラスチック製品 / 自由な形にできる,可塑(かそ)性の / 造形の,塑像の / プラスチック製の / 《話》人工的な
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/03/22 22:17:13」(JST)
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Linitis plastica |
Endoscopic image of linitis plastica, where the entire stomach is invaded with stomach cancer, leading to a leather bottle like appearance.
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Classification and external resources |
Specialty |
oncology |
ICD-10 |
C16.9 |
ICD-9-CM |
151.9 |
ICD-O |
M8142/3 |
MeSH |
D008039 |
[edit on Wikidata]
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Linitis plastica, also known as Brinton's disease or leather bottle stomach, is a morphological variant of diffuse (or infiltrating) stomach cancer.
Causes of linitis plastica could be lye ingestion or metastatic infiltration of the stomach, particularly breast and lung carcinoma.[1] It is not associated with H. pylori infection or chronic gastritis. The risk factors are undefined, except for rare inherited mutations in E-cadherin, which are found in about 50% of diffuse-type gastric carcinomas.[1]
This cancer (and most other stomach cancers) is more common in Asian countries, particularly Japan.
Contents
- 1 Presentation
- 2 Notable cases
- 3 References
- 4 External links
Presentation
Endoscopic image of linitis plastica, a type of stomach cancer where the entire stomach is invaded, leading to a leather bottle-like appearance with blood coming out of it.
Diffuse stomach cancer is characterized by the presence of poorly differentiated tumor cells. Microscopic appearance is signet ring cell carcinoma, which is tumor cells with mucin droplet that displaces the nucleus to one side.
The appearance of the stomach is like a "leather bottle".[2] It is characterized by a thick, rigid stomach wall caused by diffuse infiltration of tumor cells and extensive fibrosis.
Diarrhea may be a presenting symptom.
Notable cases
Napoleon Bonaparte and many members of his family are thought to have died from this type of cancer, although it is believed by others that he may have died from arsenic poisoning.[3]
References
- ^ a b Robbins Basic Pathology, 8th Edition
- ^ "linitis plastica" at Dorland's Medical Dictionary
- ^ Bevan S, Houlston RS (1999). "Genetic predisposition to gastric cancer". QJM : monthly journal of the Association of Physicians 92 (1): 5–10. doi:10.1093/qjmed/92.1.5. PMID 10209666.
External links
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Wikimedia Commons has media related to Linitis plastica. |
- "Carcinoma of the Stomach." at patient.info
- 67502105 at GPnotebook
Glandular and epithelial neoplasms (ICD-O 8010-8589)
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Epithelium |
Papilloma/carcinoma
(8010-8139) |
- Small cell carcinoma
- Combined small cell carcinoma
- Verrucous carcinoma
- Squamous cell carcinoma
- Basal cell carcinoma
- Transitional cell carcinoma
- Inverted papilloma
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Glands |
Adenomas/
adenocarcinomas
(8140-8429) |
Gastrointestinal |
- tract: Linitis plastica
- Familial adenomatous polyposis
- pancreas
- Insulinoma
- Glucagonoma
- Gastrinoma
- VIPoma
- Somatostatinoma
- Cholangiocarcinoma
- Klatskin tumor
- Hepatocellular adenoma/Hepatocellular carcinoma
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Urogenital |
- Renal cell carcinoma
- Endometrioid tumor
- Renal oncocytoma
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Endocrine |
- Prolactinoma
- Multiple endocrine neoplasia
- Adrenocortical adenoma/Adrenocortical carcinoma
- Hurthle cell
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Other/multiple |
- Neuroendocrine tumor
- Adenoid cystic carcinoma
- Oncocytoma
- Clear cell adenocarcinoma
- Apudoma
- Cylindroma
- Papillary hidradenoma
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Adnexal and
skin appendage (8390-8429) |
- sweat gland
- Syringocystadenoma papilliferum
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Cystic, mucinous,
and serous (8440-8499) |
Cystic general |
- Cystadenoma/Cystadenocarcinoma
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Mucinous |
- Signet ring cell carcinoma
- Mucinous cystadenoma / Mucinous cystadenocarcinoma
- Mucoepidermoid carcinoma
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Serous |
- Ovarian serous cystadenoma / Pancreatic serous cystadenoma / Serous cystadenocarcinoma / Papillary serous cystadenocarcinoma
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Ductal, lobular,
and medullary (8500-8549) |
Ductal carcinoma |
- Mammary ductal carcinoma
- Pancreatic ductal carcinoma
- Comedocarcinoma
- Paget's disease of the breast / Extramammary Paget's disease
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Lobular carcinoma |
- Lobular carcinoma in situ
- Invasive lobular carcinoma
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Medullary carcinoma |
- Medullary carcinoma of the breast
- Medullary thyroid cancer
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Acinar cell (8550-8559) |
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Other |
Complex epithelial (8560-8589) |
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- See also
- Template:Epithelium and epithelial tissue
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Digestive system neoplasia (C15–C26/D12–D13, 150–159/211)
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GI tract |
Upper |
Esophagus |
- Squamous cell carcinoma
- Adenocarcinoma
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Stomach |
- Gastric carcinoma
- Signet ring cell carcinoma
- Gastric lymphoma
- Linitis plastica
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Lower |
Small intestine |
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Appendix |
- Carcinoid
- Pseudomyxoma peritonei
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Colon/rectum |
- colorectal polyp: Peutz–Jeghers syndrome
- Juvenile polyposis syndrome
- Familial adenomatous polyposis/Gardner's syndrome
- Cronkhite–Canada syndrome
- neoplasm: Adenocarcinoma
- Familial adenomatous polyposis
- Hereditary nonpolyposis colorectal cancer
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Anus |
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Upper and/or lower |
- Gastrointestinal stromal tumor
- Krukenberg tumor (metastatic)
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Accessory |
Liver |
- malignant: Hepatocellular carcinoma
- Hepatoblastoma
- benign: Hepatocellular adenoma
- Cavernous hemangioma
- hyperplasia: Focal nodular hyperplasia
- Nodular regenerative hyperplasia
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Biliary tract |
- bile duct: Cholangiocarcinoma
- Klatskin tumor
- gallbladder: Gallbladder cancer
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Pancreas |
- exocrine pancreas: Adenocarcinoma
- Pancreatic ductal carcinoma
- cystic neoplasms: Serous microcystic adenoma
- Intraductal papillary mucinous neoplasm
- Mucinous cystic neoplasm
- Solid pseudopapillary neoplasm
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Peritoneum |
- Primary peritoneal carcinoma
- Peritoneal mesothelioma
- Desmoplastic small round cell tumor
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UpToDate Contents
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English Journal
- Gastrectomy in advanced gastric cancer effectively palliates symptoms and may improve survival in select patients.
- Collins A, Hatzaras I, Schmidt C, Carruthers K, Melvin WS, Muscarella P, Ellison EC, Martin E, Bloomston M.AbstractBACKGROUND: The role of gastrectomy in the face of incurable gastric cancer is evolving. We sought to evaluate our experience with incomplete (i.e., R2) gastrectomy in advanced gastric cancer.
- Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.J Gastrointest Surg.2014 Mar;18(3):491-6.
- BACKGROUND: The role of gastrectomy in the face of incurable gastric cancer is evolving. We sought to evaluate our experience with incomplete (i.e., R2) gastrectomy in advanced gastric cancer.METHODS: We reviewed 210 locally advanced or metastatic gastric cancers (1992-2008). Patient characteristics
- PMID 24234246
- Linitis plastica presenting two years after elective Roux-en-Y gastric bypass for treatment of morbid obesity: a case report and review of the literature.
- Nau P1, Rattner DW1, Meireles O2.Author information 1Massachusetts General Hospital, Surgery Department, Boston, Massachusetts.2Massachusetts General Hospital, Surgery Department, Boston, Massachusetts. Electronic address: Meireles.Ozanan@mgh.harvard.edu.KEYWORDS: Gastric bypass, Gastric cancer, Linitis plastic
- Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery.Surg Obes Relat Dis.2014 Mar-Apr;10(2):e15-7. doi: 10.1016/j.soard.2013.06.015. Epub 2013 Jun 19.
- PMID 24060402
Japanese Journal
- PS-052-2 Linitis plastica型スキルス胃癌の生物学的特性について(PS ポスターセッション,第113回日本外科学会定期学術集会)
- 遠藤 和也,松本 載恭,楠元 英次,山口 将平,堤 敬文,池尻 公二
- 日本外科学会雑誌 114(臨時増刊号2), 590, 2013-03-05
- NAID 110009714963
- 胃癌術後8年目に再発したlinitis plastica型大腸転移の1例
- 紙谷 直毅,頼木 領,大住 周司,吉村 淳,島田 啓司
- 日本臨床外科学会雑誌 74(12), 3398-3404, 2013
- … 腫瘍が存在し,浸潤があった空腸・脾臓・横隔膜を合併切除した.病理組織学的検査所見で結腸の粘膜下層から漿膜下組織を中心に低分化腺癌を認め,組織型が一致していることより,胃原発,linitis plastica型大腸転移と診断した.転移性大腸癌は通常のスクリーニング検査では診断できないことが多いが切除可能症例では長期予後が望めるという報告もある.自験例のような晩期転移再発を考慮に …
- NAID 130004518604
- Metastatic Breast Carcinoma Simulating Linitis Plastica of the Colon : Report of a Case
- OKIDO MASAYUKI,SEO MITSURU,HAMADA YUZO,KURIHARA SHUICHI,MATSUMOTO KOTARO,KONOMI HIROYUKI,KATO MASATO,ICHIMIYA HITOSHI
- Surgery today : the Japanese journal of surgery 41(4), 542-545, 2011-04-01
- NAID 10029046776
Related Links
- Linitis plastica, also known as Brinton's disease or leather bottle stomach, is a morphological variant of diffuse (or infiltrating) stomach cancer. Causes of linitis plastica could be lye ingestion or metastatic infiltration of the ...
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