English Journal

Methotrimeprazine-Associated Stevens-Johnson Syndrome in 2 Ashkenazi Jewish Patients.

Moubayed D1, Gifuni AJ, Tourian L.
Journal of clinical psychopharmacology.J Clin Psychopharmacol.2017 Feb;37(1):112-113. doi: 10.1097/JCP.0000000000000641.
PMID 28027113

Inhibition of human cytochrome P450 isoenzymes by a phenothiazine neuroleptic levomepromazine: An in vitro study.

Basińska-Ziobroń A1, Daniel WA1, Wójcikowski J2.
Pharmacological reports : PR.Pharmacol Rep.2015 Dec;67(6):1178-82. doi: 10.1016/j.pharep.2015.04.005. Epub 2015 Apr 23.
BACKGROUND: Inhibition of cytochrome P450 (CYP) isoenzymes is the most common cause of harmful drug-drug interactions. The present study was aimed at examining the inhibitory effect of the phenothiazine neuroleptic levomepromazine on main CYP isoenzymes in human liver.METHODS: The experiment was per
PMID 26481538

Cox L1, Darvill E, Dorman S.
The Cochrane database of systematic reviews.Cochrane Database Syst Rev.2015 Nov 2;(11):CD009420. doi: 10.1002/14651858.CD009420.pub3.
BACKGROUND: This is an updated version of the original Cochrane Review published in Issue 4, 2013, on Levomepromazine for nausea and vomiting in palliative care.Nausea and vomiting are common, distressing symptoms for patients receiving palliative care. There are several drugs which can be used to t
PMID 26524693