levodopa

出典: meddic

レボドパ L-DOPA

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「=L-dopa」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/09/30 16:27:32」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2018/12/16 04:47:56」(JST)

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英文文献

  • Effect of l-DOPA on local field potential relationship between the pedunculopontine nucleus and primary motor cortex in a rat model of Parkinson's disease.
  • Geng X1, Wang X1, Xie J2, Zhang X3, Wang X1, Hou Y1, Lei C1, Li M1, Han H1, Yao X1, Zhang Q4, Wang M5.
  • Behavioural brain research.Behav Brain Res.2016 Dec 15;315:1-9. doi: 10.1016/j.bbr.2016.08.018. Epub 2016 Aug 8.
  • Levodopa (l-DOPA) has been proved to reverse the pathologic neuron activities in many brain regions related to Parkinson's disease (PD). But little is known about the effect of l-DOPA on the altered electrophysiological coherent activities between pedunculopontine nucleus (PPN) and motor cortex. To
  • PMID 27515286
  • Catechol-O-methyltransferase Val158Met polymorphism influences prefrontal executive function in early Parkinson's disease.
  • Zhang Y1, Feng S1, Nie K1, Zhao X1, Gan R1, Wang L1, Zhao J1, Tang H1, Gao L1, Zhu R1, Wang L2, Zhang Y3.
  • Journal of the neurological sciences.J Neurol Sci.2016 Oct 15;369:347-53. doi: 10.1016/j.jns.2016.08.063. Epub 2016 Aug 31.
  • OBJECTIVE: The catechol-O-methyltransferase (COMT) Val158Met polymorphism has been proposed to be associated with increased risk of Parkinson's disease (PD) and have a specific impact on dopamine-mediated prefrontal executive function in an inverted-U curve manner. We explored the influence of this
  • PMID 27653922
  • The discovery of LRRK2 p.R1441S, a novel mutation for Parkinson's disease, adds to the complexity of a mutational hotspot.
  • Mata IF1,2, Davis MY1,2, Lopez AN3, Dorschner MO4,5, Martinez E1, Yearout D1,2, Cholerton BA1,4, Hu SC1,2, Edwards KL6, Bird TD1,2, Zabetian CP7,8.
  • American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.Am J Med Genet B Neuropsychiatr Genet.2016 Oct;171(7):925-30. doi: 10.1002/ajmg.b.32452. Epub 2016 Apr 25.
  • Mutations in the LRRK2 gene result in autosomal dominant, late onset Parkinson's disease (PD). Three such mutations (p.R1441C, p.R1441G, and p.R1441H) are known to occur within codon 1441, and haplotype analyses indicate that each one has arisen independently on multiple occasions. We sequenced the
  • PMID 27111571

和文文献

  • Severe Parkinsonism Following Endoscopic Third Ventriculostomy for Non-communicating Hydrocephalus : —Case Report—
  • AKIYAMA Takenori,TANIZAKI Yoshio,AKAJI Kazunori,HIRAGA Kenji,AKIYAMA Takekazu,TAKAO Masaki,OHIRA Takayuki
  • Neurologia medico-chirurgica 51(1), 60-63, 2011
  • … These symptoms showed marked improvement after administration of levodopa, and were not aggravated after discontinuation. …
  • NAID 130000442701
  • Direct Relief of Levodopa-Induced Dyskinesia by Stimulation in the Area Above the Subthalamic Nucleus in a Patient With Parkinson's Disease : Case Report
  • NISHIKAWA Yasumasa,KOBAYASHI Kazutaka,OSHIMA Hideki,FUKAYA Chikashi,YAMAMOTO Takamitu,KATAYAMA Yoichi,OGAWA Akira,OGASAWARA Kuniaki
  • Neurologia medico-chirurgica = 神経外科 50(3), 257-259, 2010-03-15
  • … A 71-year-old woman with a 25-year history of levodopa (LD)-responsive Parkinsons disease (PD) developed on-off motor fluctuation and severe peak dose dyskinesia. …
  • NAID 10025950896

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★リンクテーブル★
リンク元パーキンソン病治療薬」「レボドパ」「Lージヒドロキシフェニルアラニン」「L-DOPA

パーキンソン病治療薬」

  [★]

antiparkinson agent, antiparkinsonism drug
パーキンソン病薬理学

ドパミン前駆体

ドパミン受容体作動薬

MAO-B阻害薬

ドパミン放出促進

中枢性抗コリン作用

ノルアドレナリン前駆体


レボドパ」

  [★]

levodopa
L-dopaL-DOPALDLドーパL-ドーパL-ドパドパドーパ3,4-ジヒドロキシフェニルアラニン 3,4-dihydroxyphenylalanineジヒドロキシフェニルアラニン dihydroxyphenylalanine
ドパストンドパゾールドパール
[show details]



Lージヒドロキシフェニルアラニン」

  [★]

L-dopa, levodopa
L-dihydroxyphenylalanine, dihydroxyphenylalanine
L-3,4-dihydroxyphenylalanine, 3,4-dihydroxyphenylalanine
-L-dopa
Levodopa


L-DOPA」

  [★]

levodopa
Levodopa




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