WordNet

be a contributing factor; "make things factor into a companys profitability"
any of the numbers (or symbols) that form a product when multiplied together
an independent variable in statistics
anything that contributes causally to a result; "a number of factors determined the outcome"
consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
a concept whose truth can be proved; "scientific hypotheses are not facts"
a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
blood cells that engulf and digest bacteria and fungi; an important part of the bodys defense system (同)leucocyte, white_blood_cell, white_cell, white blood corpuscle, white_corpuscle, WBC

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1. 肥満細胞由来のメディエーター mast cell derived mediators
2. 血友病患者における第VIIIおよび第IX因子阻害物質 factor viii and factor ix inhibitors in patients with hemophilia
3. 肥満細胞：表面受容体とシグナル伝達 mast cells surface receptors and signal transduction
4. von Willebrand因子の生物学および正常機能 biology and normal function of von willebrand factor
5. 直接トロンビン阻害剤および直接Xa因子阻害剤による抗凝固療法 anticoagulation with direct thrombin inhibitors and direct factor xa inhibitors

Unfractionated heparin suppresses lipopolysaccharide-induced monocyte chemoattractant protein-1 expression in human microvascular endothelial cells by blocking Krüppel-like factor 5 and nuclear factor-κB pathway.

Li X1, Li X1, Zheng Z1, Liu Y1, Ma X2.
Immunobiology.Immunobiology.2014 Oct;219(10):778-85. doi: 10.1016/j.imbio.2014.06.005. Epub 2014 Jun 30.
Unfractionated heparin (UFH) and low-molecular-weight heparins (LMWH), apart from anticoagulant activities, contain a variety of biological properties such as anti-inflammatory actions possibly affecting sepsis. Chemokines are vital for promoting the movement of circulating leukocytes to the site of
PMID 25023776

Crucial involvement of the CCL3-CCR5 axis-mediated fibroblast accumulation in colitis-associated carcinogenesis in mice.

Sasaki S1, Baba T, Shinagawa K, Matsushima K, Mukaida N.
International journal of cancer. Journal international du cancer.Int J Cancer.2014 Sep 15;135(6):1297-306. doi: 10.1002/ijc.28779. Epub 2014 Feb 20.
Patients with inflammatory bowel diseases often develop colon carcinoma. Combined treatment of azoxymethane (AOM) and dextran sulfate sodium (DSS) recapitulates colitis-associated cancer in mice. AOM/DSS-induced tumor formation was reduced in CCL3- or its specific receptor, CCR5-deficient mice despi
PMID 24510316

Neutrophils recruit regulatory T-cells into tumors via secretion of CCL17--a new mechanism of impaired antitumor immunity.

Mishalian I1, Bayuh R, Eruslanov E, Michaeli J, Levy L, Zolotarov L, Singhal S, Albelda SM, Granot Z, Fridlender ZG.
International journal of cancer. Journal international du cancer.Int J Cancer.2014 Sep 1;135(5):1178-86. doi: 10.1002/ijc.28770. Epub 2014 Feb 27.
The mechanisms by which tumor-associated neutrophils (TANs) affect tumor growth are to a large extent unknown. Regulatory T-cells (T-regs) are functionally immune-suppressive subsets of T-cells. Depletion or inhibition of T-regs can enhance antitumor immunity. We demonstrated both by RT-PCR and by E
PMID 24501019

Angiopoietin-like protein 2 mediates endotoxin-induced acute inflammation in the eye

Kanda Atsuhiro,Noda Kousuke,Oike Yuichi,Ishida Susumu
Laboratory Investigation 92(11), 1553-1563, 2012-11
… Compared to wild-type animals, Angptl2^[-/-] mice significantly reduced various EIU-associated cellular and molecular parameters including leukocyte adhesion to the retinal vessels and infiltration into the vitreous cavity and retinal mRNA expression levels of monocyte chemotactic protein-1, intercellular adhesion molecule-1, interleukin (IL)-6 and tumor necrosis factor (TNF)-α, together with nuclear translocation of nuclear factor (NF)-κB p65 subunit. …
NAID 120005228682

Effects of sustained stimulation with multi-wall carbon nanotubes on immune and inflammatory responses in mice

Yamaguchi Atsumi,Fujitani Tomoko,Ohyama Ken-ichi [他],NAKAE Dai,HIROSE Akihiko,NISHIMURA Tetsuji,OGATA Akio
Journal of toxicological sciences 37(1), 177-189, 2012-02-01
… Peritoneal cells overexpressed mRNA for genes of T helper (Th)2 cytokines (interleukin [IL]-4, IL-5, and IL-13), Th17 cytokine (IL-17), pro-inflammatory cytokines/chemokines (IL-1β, IL-33, tumor necrosis factor α, and monocyte chemotactic protein-1), and myeloid differentiation factor 88 for at least 2 weeks after the administration of MWCNTs, while those of Th1 cytokine genes (IL-2 and interferon γ) were overexpressed several weeks later and expression levels remained high up to 20 weeks. …
NAID 10030037786

Matsushima Kouji,Terashima Yuya,Toda Etsuko,Shand Francis,Ueha Satoshi
Inflammation and Regeneration 31(1), 11-22, 2011
… Nearly two decades have passed since our discovery of the prototypic chemokines, a neutrophil chemotactic factor interleukin 8 (IL 8, CXCL8) and monocyte chemotactic factor MCAF/MCP-1 (CCL2) at the National Cancer Institute, USA. … The characterization of chemokines has revealed the molecular mechanisms underlying specific leukocyte subset infiltration into inflammatory tissues, previously a long-standing enigma in inflammation research. …
NAID 130004943765