large ribosome subunit

• リボソーム大サブユニット

WordNet

1. with the wind abaft the beam; "a ship sailing large"
2. a garment size for a large person
3. above average in size or number or quantity or magnitude or extent; "a large city"; "set out for the big city"; "a large sum"; "a big (or large) barn"; "a large family"; "big businesses"; "a big expenditure"; "a large number of newspapers"; "a big group of scientists"; "large areas of the world" (同)big
4. at a distance, wide of something (as of a mark)
5. fairly large or important in effect; influential; "played a large role in the negotiations"
6. having broad power and range and scope; "taking the large view"; "a large effect"; "a large sympathy"
7. an organelle in the cytoplasm of a living cell; they attach to mRNA and move down it one codon at a time and then stop until tRNA brings the required amino acid; when it reaches a stop codon it falls apart and releases the completed protein molecule for u

PrepTutorEJDIC

1. (同じ種類のものと比較して,形・体積・数量などが)『大きい』,多い,広い / (考えなどが)広範囲な,幅の広い,寛大な / 大きく / 自慢して,誇大に
2. リボゾーム(細胞質に含まれ,蛋白質とリボ核酸から成る微小粒子)

UpToDate Contents

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• 1. 大顆粒T細胞リンパ球性白血病の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of t cell large granular lymphocyte leukemia
• 2. びまん性大細胞型B細胞性リンパ腫の疫学、臨床症状、病理学的特徴、および診断 epidemiology clinical manifestations pathologic features and diagnosis of diffuse large b cell lymphoma
• 3. 原発性縦隔大細胞型B細胞リンパ腫 primary mediastinal large b cell lymphoma
• 4. ナチュラルキラー（NK）細胞大顆粒リンパ球性白血病 natural killer nk cell large granular lymphocyte leukemia
• 5. 原発性皮膚大細胞型B細胞性リンパ腫、下肢型 primary cutaneous large b cell lymphoma leg type

English Journal

• Inhibition of Escherichia coli ribosome subunit dissociation by chloramphenicol and Blasticidin: a new mode of action of the antibiotics.

• Pathak BK1, Mondal S1, Barat C1.
• Letters in applied microbiology.Lett Appl Microbiol.2017 Jan;64(1):79-85. doi: 10.1111/lam.12686. Epub 2016 Nov 24.
• The ability of the ribosome to assist in folding of proteins both in vitro and in vivo is well documented and is a nontranslational function of the ribosome. The interaction of the unfolded protein with the peptidyl transferase centre (PTC) of the bacterial large ribosomal subunit is followed by r
• PMID 27739094

• The NMR solution structure and function of RPA3313: a putative ribosomal transport protein from Rhodopseudomonas palustris.

• Catazaro J1, Lowe AJ1, Cerny RL1, Powers R1.
• Proteins.Proteins.2017 Jan;85(1):93-102. doi: 10.1002/prot.25201. Epub 2016 Nov 13.
• Protein function elucidation often relies heavily on amino acid sequence analysis and other bioinformatics approaches. The reliance is extended to structure homology modeling for ligand docking and protein-protein interaction mapping. However, sequence analysis of RPA3313 exposes a large, unannotate
• PMID 27802574

• Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions.

• Graf M1, Arenz S1, Huter P1, Dönhöfer A1, Nováček J2, Wilson DN3,4.
• Nucleic acids research.Nucleic Acids Res.2016 Dec 15. pii: gkw1272. [Epub ahead of print]
• Ribosomes are the protein synthesizing machines of the cell. Recent advances in cryo-EM have led to the determination of structures from a variety of species, including bacterial 70S and eukaryotic 80S ribosomes as well as mitoribosomes from eukaryotic mitochondria, however, to date high resolution
• PMID 27986857

Japanese Journal

• リボソームにおけるペプチド生成機構の起源

• 田村 浩二
• Viva origino 39(1-4), 31-37, 2012-06-20
• … Peptide bond formation catalyzed on the ribosome is a crucial event in the life on earth. … The ribosome is a supercomplex of ribonucleoprotein particles containing both RNAs and proteins, and the peptide bond is produced on the peptidyl transferase center (PTC) of the large subunit of the ribosome. … The high-resolution structures of the ribosome showed that the PTC is composed of only RNA. …
• NAID 110009470535

• Structural Insights into the Functions of the Large Ribosomal Subunit, a Major Antibiotic Target

• STEITZ Thomas A.
• Keio journal of medicine 57(1), 1-14, 2008-03-01
• NAID 10024174082

• Induction of a Ribotoxic Stress Response That Stimulates Stress-Activated Protein Kinases by 13-Deoxytedanolide, an Antitumor Marine Macrolide

• Lee Kun-Hyung,Nishimura Shinichi,Matsunaga Shigeki [他],FUSETANI Nobuhiro,ICHIJO Hidenori,HORINOUCHI Sueharu,YOSHIDA Minoru
• Bioscience, biotechnology, and biochemistry 70(1), 161-171, 2006-01-23
• … Recently, we showed that 13-deoxytedanolide bound to the large subunit of the yeast ribosome and inhibited polypeptide elongation <I>in vitro</I>, but the mechanism by which it exerts antitumor activity is still unknown. …
• NAID 10018535381

Related Links

• リボソーム - Wikipedia

リボソームは、RNAの情報からタンパク質を合成するという容易ならざる作業を正確に 行うため、大きく複雑な構造体となっている。リボソームは50種類以上 .... “The complete atomic structure of the large ribosomal subunit at 2.4 A resolution”. Science 289 ...

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★リンクテーブル★

リンク元	「リボソーム大サブユニット」
拡張検索	「eukaryotic large ribosome subunit」「archaeal large ribosome subunit」「bacterial large ribosome subunit」
関連記事	「large」「ribosome subunit」

「リボソーム大サブユニット」

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英

large ribosome subunit

「eukaryotic large ribosome subunit」

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• 真核生物リボソーム大サブユニット

「archaeal large ribosome subunit」

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• 古細菌リボソーム大サブユニット

「bacterial large ribosome subunit」

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• 細菌リボソーム大サブユニット

「large」

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• adj.

• (比較級larger-最上級largest)大きい、大型の

関

great、massive、sizable

　 　 　 　 　 　 　

「ribosome subunit」

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• リボソームサブユニット

関

ribosomal subunit