large clinical trial

• 大規模臨床治験

WordNet

1. (law) the determination of a persons innocence or guilt by due process of law; "he had a fair trial and the jury found him guilty"; "most of these complaints are settled before they go to trial"
2. trying something to find out about it; "a sample for ten days free trial"; "a trial of progesterone failed to relieve the pain" (同)trial_run, test, tryout
3. an annoying or frustrating or catastrophic event; "his mother-in-laws visits were a great trial for him"; "life is full of tribulations"; "a visitation of the plague" (同)tribulation, visitation
4. (sports) a preliminary competition to determine qualifications; "the trials for the semifinals began yesterday"
5. with the wind abaft the beam; "a ship sailing large"
6. a garment size for a large person
7. above average in size or number or quantity or magnitude or extent; "a large city"; "set out for the big city"; "a large sum"; "a big (or large) barn"; "a large family"; "big businesses"; "a big expenditure"; "a large number of newspapers"; "a big group of scientists"; "large areas of the world" (同)big
8. at a distance, wide of something (as of a mark)
9. fairly large or important in effect; influential; "played a large role in the negotiations"
10. having broad power and range and scope; "taking the large view"; "a large effect"; "a large sympathy"
11. a healthcare facility for outpatient care
12. a medical establishment run by a group of medical specialists
13. meeting for diagnosis of problems and instruction or remedial work in a particular activity
14. scientifically detached; unemotional; "he spoke in the clipped clinical monotones typical of police testimony"
15. relating to a clinic or conducted in or as if in a clinic and depending on direct observation of patients; "clinical observation"; "clinical case study"

PrepTutorEJDIC

1. 〈U〉〈C〉『裁判』,公判,審理 / 〈U〉〈C〉(…の)『試験』,ためし《+of+名》 / 〈C〉企て,試み;努力 / 〈C〉(忍耐・徳・信仰などをためす)試練,苦難 / 〈C〉困りもの,迷惑な(やっかいな)人(もの)
2. (同じ種類のものと比較して,形・体積・数量などが)『大きい』,多い,広い / (考えなどが)広範囲な,幅の広い,寛大な / 大きく / 自慢して,誇大に
3. 〈U〉(医学の)臨床講義 / 〈C〉《集合的に》臨床講義のクラス / 〈C〉臨床講義室 / 〈C〉(病院・医科大学・社会事業団などに付属した)診療所;《形容詞を判って》医療施設,病院 / 〈C〉(警察・学校・社会事業団などに付属した)相談所
4. 臨床の,臨床講義の / 病床の / 臨床的な,客観的な態度の

UpToDate Contents

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• 1. 頭蓋内大血管の動脈硬化 intracranial large artery atherosclerosis
• 2. 急性虚血性脳卒中に対する再灌流療法 reperfusion therapy for acute ischemic stroke
• 3. 心血管疾患または糖尿病患者におけるコレステロール低下に関する臨床試験 clinical trials of cholesterol lowering in patients with cardiovascular disease or diabetes
• 4. 大顆粒リンパ球性白血病の治療 treatment of large granular lymphocyte leukemia
• 5. 進行期びまん性大細胞型B細胞性リンパ腫の初期治療 initial treatment of advanced stage diffuse large b cell lymphoma

English Journal

• Task-related fMRI responses to a nicotinic acetylcholine receptor partial agonist in schizophrenia: A randomized trial.

• Barch DM1, Marder SR2, Harms MP3, Jarskog LF4, Buchanan RW5, Cronenwett W6, Chen LS7, Weiss M8, Maguire RP9, Pezous N10, Feuerbach D11, Lopez-Lopez C12, Johns DR13, Behrje RB14, Gomez-Mancilla B15.
• Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2016 Nov 3;71:66-75. doi: 10.1016/j.pnpbp.2016.06.013. Epub 2016 Jun 28.
• INTRODUCTION: AQW051, an α7-nicotinic acetylcholine receptor partial agonist, enhanced cognitive function in rodent models of learning and memory. This study evaluated brain activation during performance of a working memory task (WMT) and an episodic memory task (EMT), and the effect of AQW051 on t
• PMID 27371157

• Three measures of explained variation for correlated survival data under the proportional hazards mixed-effects model.

• Honerkamp-Smith G1, Xu R1,2.
• Statistics in medicine.Stat Med.2016 Oct 15;35(23):4153-65. doi: 10.1002/sim.6993. Epub 2016 May 30.
• Measures of explained variation are useful in scientific research, as they quantify the amount of variation in an outcome variable of interest that is explained by one or more other variables. We develop such measures for correlated survival data, under the proportional hazards mixed-effects model.
• PMID 27241815

• Hepatitis E: prevention and treatment.

• Nelson KE1, Heaney CD, Labrique AB, Kmush BL, Krain LJ.
• Current opinion in infectious diseases.Curr Opin Infect Dis.2016 Oct;29(5):478-85. doi: 10.1097/QCO.0000000000000294.
• PURPOSE OF REVIEW: Infection with the hepatitis E virus (HEV) is very common worldwide. The epidemiology, viral genotypes, and transmission routes differ between low-resource countries and economically developed countries. These differences have resulted in the design of diverse prevention and treat
• PMID 27454402

Japanese Journal

• R-mini CHP in ≥80-year-old Patients with Diffuse Large B-cell Lymphoma: A Multicenter, Open-label, Single-arm Phase II Trial Protocol

• Acta Medica Okayama 72(3), 315-318, 2018-06
• NAID 120006482828

• Effectiveness of influenza vaccination for children in Japan: Four-year observational study using a large-scale claims database

• Vaccine 36(20), 2809-2815, 2018-05-11
• NAID 120006469172

• An Efficient Procedure for Calculating Sample Size Through Statistical Simulations

• Statistics in Biopharmaceutical Research 10(1), 1-8, 2018-03
• NAID 120006471239

Related Links

• Large Simple Trials | Clinical Trials Transformation Initiative

Facilitating the Use of Large Simple Trials (LST) A large simple trial (LST) is a type of randomized clinical trial (RCT) ideally suited to answer many important clinical questions and because it typically answers only one or 2 questions ...

• Large Randomized Clinical Trials - Improving Medical Statistics

Strengths and potential weaknesses of large randomized clinical trials. Very large randomized trials can have significant problems in trial construction and interpretation. The very large randomized clinical trial has many significant ...

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★リンクテーブル★

関連記事	「trial」「clinical trial」「large」「clinical」「clinic」

「trial」

　　[★]

• n.

• 試行、試み、(臨床)治験、試験

関

assessment、attempt、clinical research、clinical study、clinical test、clinical trial、effort、exam、examination、examine、investigation、investigational、tentative、tentatively、test、testing

　 　 　 　 　

「clinical trial」

　　[★]

• 臨床治験、臨床試験、治験

関

clinical research、clinical study、clinical test、investigation、investigational、trial

「large」

　　[★]

• adj.

• (比較級larger-最上級largest)大きい、大型の

関

great、massive、sizable

　 　 　 　 　 　 　

「clinical」

　　[★]

• adj.

• 臨床の、臨床的な、臨床上の、クリニカル

関

clin、clinically

　 　 　

「clinic」

　　[★]

• n.

• クリニック、臨床講義、診療所