large-conductance calcium-activated potassium channel

出典: meddic

大コンダクタンスカルシウム活性化カリウムチャネル大コンダクタンスカルシウム依存性カリウムチャネル

BK channel

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英文文献

  • Mitochondrial large-conductance potassium channel from Dictyostelium discoideum.
  • Laskowski M1, Kicinska A2, Szewczyk A1, Jarmuszkiewicz W3.
  • The international journal of biochemistry & cell biology.Int J Biochem Cell Biol.2015 Mar;60:167-75. doi: 10.1016/j.biocel.2015.01.006. Epub 2015 Jan 14.
  • In the present study, we describe the existence of a large-conductance calcium-activated potassium (BKCa) channel in the mitochondria of Dictyostelium discoideum. A single-channel current was recorded in a reconstituted system, using planar lipid bilayers. The large-conductance potassium channel act
  • PMID 25596489
  • Kaempferol enhances endothelium-dependent relaxation in the porcine coronary artery through activation of large-conductance Ca2+ -activated K+ channels.
  • Xu YC1, Leung SW, Leung GP, Man RY.
  • British journal of pharmacology.Br J Pharmacol.2015 Feb 5. doi: 10.1111/bph.13108. [Epub ahead of print]
  • BACKGROUND AND PURPOSE: Kaempferol, a plant flavonoid present in the normal human diet, can modulate vasomotor tone. The present study aimed to elucidate the signaling pathway through which this flavonoid enhances relaxation of vascular smooth muscle.EXPERIMENTAL APPROACH: The effect of kaempferol o
  • PMID 25652142
  • Rottlerin-Induced BKCa Channel Activation Impairs Specific Contractile Responses and Promotes Vasodilation.
  • Cordeiro B1, Shinn C1, Sellke FW1, Clements RT2.
  • The Annals of thoracic surgery.Ann Thorac Surg.2015 Feb;99(2):626-34. doi: 10.1016/j.athoracsur.2014.07.091. Epub 2014 Dec 17.
  • BACKGROUND: Activation of large conductance calcium-activated potassium (BKCa) channels is cardioprotective for ischemic injury and can enhance vasorelaxation. Rottlerin has recently been identified as a potent BKCa activator. We demonstrated that rottlerin improves cardiac function and increases co
  • PMID 25527424

和文文献

  • Relaxation Induced by Atrial Natriuretic Peptide Is Impaired in Carotid but Not Renal Arteries from Spontaneously Hypertensive Rats Due to Reduced BK<sub>Ca</sub> Channel Activity
  • 高血圧自然発症ラットの内皮依存性過分極因子反応におけるカルシウム活性化カリウムチャネルの障害
  • Rat GnRH Neurons Exhibit Large Conductance Voltage- and Ca^<2+>-Activated K^+ (BK) Currents and Express BK Channel mRNAs
  • The journal of physiological sciences : JPS 58(1), 21-29, 2008-02-01
  • NAID 10022597577

関連リンク

1. BJU Int. 2012 Oct;110(8 Pt B):E402-8. doi: 10.1111/j.1464-410X.2012.11137.x. Epub 2012 Apr 23. Large-conductance calcium-activated potassium channel activity, as determined by whole-cell patch clamp recording, is decreased ...
1. Korean J Pediatr. 2014 Oct;57(10):445-50. doi: 10.3345/kjp.2014.57.10.445. Epub 2014 Oct 31. The large-conductance calcium-activated potassium channel holds the key to the conundrum of familial hypokalemic ...

関連画像

Large-Conductance Calcium-Activated FIGURE 1. Schematic representation of the Large-Conductance Calcium-Activated Large-Conductance Calcium-Activated Large-Conductance Calcium-Activated Frontiers in Bioscience 4198-4217, May 1


★リンクテーブル★
リンク元大コンダクタンスカルシウム活性化カリウムチャネル」「BK channel」「大コンダクタンスカルシウム依存性カリウムチャネル
拡張検索large-conductance calcium-activated potassium channel beta subunit」「large-conductance calcium-activated potassium channel alpha subunit
関連記事channel」「large」「activate」「activated」「potassium

大コンダクタンスカルシウム活性化カリウムチャネル」

  [★]

large-conductance calcium-activated potassium channelBK channel
大コンダクタンスカリウムチャネルBKチャネル大コンダクタンスカルシウム依存性カリウムチャネル


BK channel」

  [★]

large-conductance calcium-activated potassium channel


大コンダクタンスカルシウム依存性カリウムチャネル」

  [★]

large-conductance calcium-activated potassium channel
大コンダクタンスカルシウム活性化カリウムチャネル


large-conductance calcium-activated potassium channel beta subunit」

  [★]


large-conductance calcium-activated potassium channel alpha subunit」

  [★]


channel」

  [★]

  • n.
  • 川床、川底。水路、河道
  • 海峡
  • 水管、導管
  • 経路、ルート。道筋、方向
ion channelionic channel

WordNet   license wordnet

「direct the flow of; "channel information towards a broad audience"」
canalize, canalise

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「a television station and its programs; "a satellite TV channel"; "surfing through the channels"; "they offer more than one hundred channels"」
television channel, TV channel

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「a passage for water (or other fluids) to flow through; "the fields were crossed with irrigation channels"; "gutters carried off the rainwater into a series of channels under the street"」

WordNet   license wordnet

「(often plural) a means of communication or access; "it must go through official channels"; "lines of communication were set up between the two firms"」
communication channel, line

WordNet   license wordnet

「a path over which electrical signals can pass; "a channel is typically what you rent from a telephone company"」
transmission channel

WordNet   license wordnet

「a deep and relatively narrow body of water (as in a river or a harbor or a strait linking two larger bodies) that allows the best passage for vessels; "the ship went aground in the channel"」

PrepTutorEJDIC   license prepejdic

「〈C〉『水路』(川・湾・運河の船の通行ができる深い部分) / 〈U〉河床・川底 / 〈C〉『海峡』 / 〈C〉みぞ(groove),(道路の)水渠(すいきょ) / 《複数形で》(運搬・伝達の)正式の経路(手続き);(一般に)経路 / 〈C〉(テレビ・ラジオの)チャンネル / …‘に'水路を開く / …‘に'みぞを堀る / …'を'伝える,流す」


large」

  [★]

  • adj.
greatmassivesizable

WordNet   license wordnet

「with the wind abaft the beam; "a ship sailing large"」

WordNet   license wordnet

「a garment size for a large person」

PrepTutorEJDIC   license prepejdic

「(同じ種類のものと比較して,形・体積・数量などが)『大きい』,多い,広い / (考えなどが)広範囲な,幅の広い,寛大な / 大きく / 自慢して,誇大に」

WordNet   license wordnet

「above average in size or number or quantity or magnitude or extent; "a large city"; "set out for the big city"; "a large sum"; "a big (or large) barn"; "a large family"; "big businesses"; "a big expenditure"; "a large number of newspapers"; "a big group of scientists"; "large areas of the world"」
big

WordNet   license wordnet

「at a distance, wide of something (as of a mark)」

WordNet   license wordnet

「fairly large or important in effect; influential; "played a large role in the negotiations"」

WordNet   license wordnet

「having broad power and range and scope; "taking the large view"; "a large effect"; "a large sympathy"」


activate」

  [★]

  • v.
  • 活性化する、賦活化する、賦活する
activatedactivationturn on

WordNet   license wordnet

「aerate (sewage) so as to favor the growth of organisms that decompose organic matter」
aerate

WordNet   license wordnet

「make (substances) radioactive」

WordNet   license wordnet

「make active or more active; "activate an old file"」

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「make more adsorptive; "activate a metal"」

PrepTutorEJDIC   license prepejdic

「…'を'活動的にする / …‘に'放射能を与える / 〈物質〉'を'活性化する」


activated」

  [★]

  • adj.
  • 活性化の、活性化型の、賦活化の
activateactivated formactivationturn on

WordNet   license wordnet

「rendered active; e.g. rendered radioactive or luminescent or photosensitive or conductive」

WordNet   license wordnet

「(of e.g. a molecule) made reactive or more reactive」
excited

WordNet   license wordnet

「(military) set up and placed on active assignment; "a newly activated unit"」

WordNet   license wordnet

「(of sewage) treated with aeration and bacteria to aid decomposition」


potassium」

  [★] カリウム

WordNet   license wordnet

「a light soft silver-white metallic element of the alkali metal group; oxidizes rapidly in air and reacts violently with water; is abundant in nature in combined forms occurring in sea water and in carnallite and kainite and sylvite」
K, atomic number 19

PrepTutorEJDIC   license prepejdic

「ポタシウム,カリウム(金属元素;化学記号はK)」




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