English Journal

Recent horizontal transfer, functional adaptation and dissemination of a bacterial group II intron.

LaRoche-Johnston F1, Monat C1, Cousineau B2.
BMC evolutionary biology.BMC Evol Biol.2016 Oct 20;16(1):223.
BACKGROUND: Group II introns are catalytically active RNA and mobile retroelements present in certain eukaryotic organelles, bacteria and archaea. These ribozymes self-splice from the pre-mRNA of interrupted genes and reinsert within target DNA sequences by retrohoming and retrotransposition. Evolut
PMID 27765015

Secretion of an immunoreactive single-chain variable fragment antibody against mouse interleukin 6 by Lactococcus lactis.

Shigemori S1,2, Ihara M1,3, Sato T4, Yamamoto Y1,2, Nigar S1,5, Ogita T3, Shimosato T6,7,8.
Applied microbiology and biotechnology.Appl Microbiol Biotechnol.2016 Oct 8. [Epub ahead of print]
Interleukin 6 (IL-6) is an important pathogenic factor in development of various inflammatory and autoimmune diseases and cancer. Blocking antibodies against molecules associated with IL-6/IL-6 receptor signaling are an attractive candidate for the prevention or therapy of these diseases. In this st
PMID 27722916

Sasikumar P1, Paul E1, Gomathi S1, Abhishek A1, Sasikumar S1, Selvam GS2.
Journal of basic microbiology.J Basic Microbiol.2016 Oct;56(10):1107-1116. doi: 10.1002/jobm.201500746. Epub 2016 Apr 27.
The usage of recombinant lactic acid bacteria for delivery of therapeutic proteins to the mucosa has been emerging. In the present study, an attempt was made to engineer a thyA mutant of Lactobacillus plantarum (L. plantarum) using lactococcal group II intron Ll.LtrB for the development of biologica
PMID 27119622