English Journal

Screening procedure for detection of non-steroidal anti-inflammatory drugs and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography-mass spectrometry after extractive methylation.

Maurer HH, Tauvel FX, Kraemer T.SourceDepartment of Experimental and Clinical Toxicology, University of Saarland, Homburg, Germany. hans.maurer@med-rz.unisaarland.de
Journal of analytical toxicology.J Anal Toxicol.2001 May-Jun;25(4):237-44.
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used as analgesic and anti-rheumatic drugs, and they are often misused. A gas chromatographic-mass spectrometric (GC-MS) screening procedure was developed for their detection in urine as part of a systematic toxicological analysis procedure f
PMID 11386636

Binding of kebuzone to human serum albumin studied by high performance liquid affinity chromatography.

Zhivkova ZD, Russeva VN.SourceFaculty of Pharmacy, Medical University, Sofia, Bulgaria.
Arzneimittel-Forschung.Arzneimittelforschung.2000 Mar;50(3):272-5.
The binding of the anti-inflammatory agent kebuzone (CAS 853-34-9) to human serum albumin (HSA) was examined by means of high performance liquid affinity chromatography. Phenylbutazone and diazepam, the binding properties of which were an object of our previous work, were used as markers for the maj
PMID 10758780

Japanese Journal

Seno Hiroshi,Kumazawa Takeshi,Ishii Akira,Watanabe Kanako,Suzuki Osamu
1994-09-15
… For pyrazolidines, molecular or quasi-molecular anions were small or missing except for ketophenylbutazone. …
NAID 120005314008

Characterization of High Affinity Binding Sites of Non-steroidal Anti-inflammatory Drugs with Respect to Site-Specific Probes on Human Serum Albumin

/ 山崎啓之,山崎啓之,辛英姫,林嘉虔,小田切優樹
Biological and Pharmaceutical Bulletin 16(11), 1169-1174, 1993-11-15
… A site-oriented study of nine non-steroidal anti-inflammatory drugs (NSAIDs), suprofen, ibuprofen, diclofenac sodium, pirprofen, flurbiprofen, ketoprofen, phenylbutazone, oxyphenbutazone, and ketophenylbutazone, on human serum albumin (HSA) was carried out at pH 7.4 by various direct and indirect methods to gain insignt into the high affinity binding sites of NSAIDs. …
NAID 110003663269

Classification of Drugs on the Basis of Bilirubin-Displacing Effect on Human Serum Albumin

丸山一雄,原田せつ子,西郡秀夫,岩鶴素治
Chemical & pharmaceutical bulletin 32(6), 2414-2420, 1984-06-25
… Oxyphenbutazone, phenylbutazone, sulfinpyrazone, ketophenylbutazone, glibenclamide, tolbutamide, sulfisoxazole, warfarin, salicylic acid and furosemide (group I drugs) effciently displaced bilirubin. …
NAID 110003663610