keratolytic

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keratolysis、keratolytic agent

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/03/26 10:50:53」(JST)

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[Wiki en表示]

Keratolytic (pron.: /ˌkɛrətɵˈlɪtɨk/) therapy is treatment to remove warts and other lesions in which the epidermis produces excess skin. In this therapy, acid medicine, such as salicylic acid is put on the lesion. Keratolytic therapy thins the skin on and around the lesion. It causes the outer layer of the skin to loosen and shed.

Keratolytics can also be used to soften keratin, a major component of the skin. This serves to improve the skin's moisture binding capacity, which is beneficial in the treatment of dry skin. Such agents (keratolytics) include urea, lactic acid, and allantoin.

While cytostatic agents such as zinc pyrithione are first line, keratolytics (salicylic acid and sulfur) can also be used in the treatment of dandruff and seborrheic dermatitis.

Sulfur and salicylic acid can also be used to effectively treat acne and cradle cap in some patients. Resorcinol is another keratolytic that is usually combined with sulfur. Urea acts as a keratolytic due to its hygroscopic property.

See also

• Treatment of warts by keratolysis

References

UpToDate Contents

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• 1. 汗孔角化症 porokeratosis
• 2. 肝斑 melasma
• 3. 紅色陰癬 erythrasma
• 4. 成人におけるサリチル酸（アスピリン）中毒 salicylate aspirin poisoning in adults
• 5. 皮膚扁平上皮癌の治療および予後 treatment and prognosis of cutaneous squamous cell carcinoma

English Journal

• Efficacy of Iralfaris shampoo in the treatment of scalp psoriasis: a videodermoscopy evaluation prospective study in 70 patients.

• Rossi A, Pranteda G, Iorio A, Mari E, Milani M.SourceDepartment of Internal Medicine, La Sapienza University, Rome, Italy - alfredo.rossi@uniromal.it.
• Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia.G Ital Dermatol Venereol.2012 Dec;147(6):625-30.
• AIM: This work has the aim to test the sensibility of VSCAPSI method in the evaluation of effectiveness of a medicated shampoo for the treatment of scalp psoriasis. Psoriasis is a chronic inflammatory skin disease histologically characterized by proliferation and loss of differentiation of keratinoc
• PMID 23149708

• Adhesion and proliferation of human osteoblast-like cells on different biodegradable implant materials used for graft fixation in ACL-reconstruction.

• Bernstein A, Tecklenburg K, Südkamp P, Mayr HO.SourceDepartment of Orthopaedics and Trauma Surgery, University of Freiburg, Freiburg, Germany.
• Archives of orthopaedic and trauma surgery.Arch Orthop Trauma Surg.2012 Nov;132(11):1637-45. doi: 10.1007/s00402-012-1592-6. Epub 2012 Aug 4.
• INTRODUCTION: This study investigates the adhesion and proliferation behaviour of human osteoblast-like cells over time when incubated on surfaces of biodegradable screws and pins used for graft fixation in ACL reconstruction.MATERIALS AND METHODS: 2 mm-sized-wedges of four bioresorbable implants [1
• PMID 22864871

• Retinoic acid and tumor necrosis factor-α induced monocytic cell gene expression is regulated in part by induction of transcription factor MafB.

• Zhang Y, Chen Q, Ross AC.SourceThe Pennsylvania State University, Department of Nutritional Sciences, 110 Chandlee Laboratory, University Park, PA 16802, United States.
• Experimental cell research.Exp Cell Res.2012 Nov 1;318(18):2407-16. doi: 10.1016/j.yexcr.2012.07.011. Epub 2012 Jul 20.
• All-trans-retinoic acid (RA), the major active metabolite of vitamin A, is a regulator of gene expression with many roles in cell differentiation. In the present study, we investigated RA in the regulation of MafB, a basic leucine-zipper transcription factor with broad roles in embryonic development
• PMID 22820162

Japanese Journal

• A NEW LIGHTENING APPROACH TO ACNE TREATMENT-COMBINING THERAPY MODALITIES FOR MAXIMIZING ACNE TREATMENT: PHOTOTHERAPY (LHE), DRUGS, SKIN REJUVENATION AND SKIN TIGHTENING

• LASER THERAPY 20(1), 35-37, 2011
• NAID 130004872487

• KID (Keratitis, Ichthyosis, Deafness) 症候群の1例

• 西日本皮膚科 = The Nishinihon journal of dermatology 62(1), 23-27, 2000-02-01
• NAID 10019105079

• 難治性足底ゆうぜいの１０％尿素軟膏療法

• 皮膚 42(5), 498-502, 2000
• NAID 130003844150

Related Links

• Keratolytic | Define Keratolytic at Dictionary.com

Keratolytic definition, the loosening or shedding of the horny layer of the epidermis. See more. Thesaurus Translate Puzzles & Games Reference Word of the Day Blog Slideshows Apps by Dictionary My Account Log Out Log In ...

• keratolytic - definition of keratolytic by Medical dictionary

keratolytic /ker·a·to·lyt·ic/ (ker″ah-to-lit´ik) pertaining to, characterized by, or producing keratolysis, or an agent that so acts. Keratolytic An agent that dissolves or breaks down the outer layer of skin (keratins). Mentioned in: Ichthyosis

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「角質溶解薬」

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英

keratolytic、keratolytic agent

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角質溶解

「角質溶解」

　　[★]

英

keratolysis、keratolytic

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角質溶解薬

「keratolysis」

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• 角質溶解

関

keratolytic

「keratolytic agent」

　　[★]

• 角質溶解薬

関

keratolytic