イソシアネート中毒
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- 1. 職業性喘息：管理、予後と予防occupational asthma management prognosis and prevention [show details]
…efficacy of reducing exposure levels has been demonstrated for acid anhydrides, detergent enzymes, isocyanates, laboratory animals, and latex . As examples, a threshold for flour exposure of 0.2 mcg/m3 …
- 2. 過敏性肺炎（外因性アレルギー性肺胞炎）：疫学、原因、発症機序hypersensitivity pneumonitis extrinsic allergic alveolitis epidemiology causes and pathogenesis [show details]
…etiologies of HP by occupation and the major causative antigens . A few organic chemical compounds (eg, isocyanates, mellitic anhydrides) are associated with HP . Farmer lung is, as noted above, one of the most…
- 3. 呼気中一酸化窒素の分析および適用exhaled nitric oxide analysis and applications [show details]
…FENO, including allergens, plicatic acid (the etiologic agent of Western red cedar asthma), isocyanates, and hyperventilation of cold-dry air . Levels of FENO correlate with bronchial reactivity…
- 4. 職業性喘息：病因occupational asthma pathogenesis [show details]
…increased compared to healthy controls Similar findings were described in reports of subjects with isocyanate- and Western red cedar-related asthma . Animal models have suggested that profibrotic cytokines …
- 5. 職業性喘息：定義、疫学、原因、および危険因子occupational asthma definitions epidemiology causes and risk factors [show details]
English Journal
- Sulforaphane Potentially Ameliorates Arsenic Induced Hepatotoxicity in Albino Wistar Rats: Implication of PI3K/Akt/Nrf2 Signaling Pathway.
- Thangapandiyan S, Ramesh M, Hema T, Miltonprabu S, Uddin MS, Nandhini V, Bavithra Jothi G.
- Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2019 ;52(5)1203-1222.
- Agriculture and industrial expansion in recent years have resulted in the undue discharge of arsenic into the environment, building arsenic toxicity a major worldwide anxiety. Oxidative stress is considered as the most conspicuous effect of arsenic toxicity. The current study was designed to evaluat
- PMID 31001960
- Basal PPARα inhibits bile acid metabolism adaptation in chronic cholestatic model induced by α-naphthylisothiocyanate.
- Hua H, Dai M, Luo Y, Lin H, Xu G, Hu X, Xu L, Zhang H, Tang Z, Chang L, Liu A, Yang J.
- Toxicology letters. 2019 Jan;300()31-39.
- Cholestasis is one of the most challenging diseases to be treated in current hepatology. However little is known about the adaptation difference and the underlying mechanism between acute and chronic cholestasis. In this study, wild-type and Pparα-null mice were orally administered diet containing
- PMID 30352267
- Pharmacokinetic and Pharmacodynamic Properties of Rosmarinic Acid in Rat Cholestatic Liver Injury.
- Min J, Chen H, Gong Z, Liu X, Wu T, Li W, Fang J, Huang T, Zhang Y, Zhao W, Zhu C, Wang Q, Mi S, Wang N.
- Molecules (Basel, Switzerland). 2018 Sep;23(9).
- The objective of this study was to evaluate the hepatoprotective and metabolic effects of rosmarinic acid (RA) in rats. RA [100 mg/kg body weight (BW)] was intragastrically (i.g.) administered to Sprague-Dawley (SD) rats once a day for seven consecutive days. The rats were then i.g. administered α-
- PMID 30205454
Japanese Journal
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- Hi, I am a automobile painter. For the past few years I have gradually been feeling not well. I work in a shop that has very poor ventilation and no exhaust fans. In the last 6 months or so, I have been having strange symptoms pop up.
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