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• 1. 鉄欠乏性貧血を有する成人の治療 treatment of the adult with iron deficiency anemia
• 2. 幼児および若齢小児における鉄欠乏：治療 iron deficiency in infants and young children treatment
• 3. 成人におけるレストレスレッグ症候群の治療 treatment of restless legs syndrome in adults
• 4. 小児におけるむずむず脚（レストレスレッグス）症候群と周期性四肢運動障害 restless legs syndrome and periodic limb movement disorder in children
• 5. 思春期における鉄の所要量および鉄欠乏 iron requirements and iron deficiency in adolescents

英文文献

• Diminution of 2,3,5-triphenyltetrazolium chloride toxicity on Listeria monocytogenes growth by iron source addition to the culture medium.

• Junillon T, Flandrois JP.Author information Université de Lyon 1, F-69000 Lyon, CNRS, UMR5558, Laboratoire de Biométrie et Biologie Evolutive, F-69622 Villeurbanne, France; bioMerieux SA département Microbiologie industrielle, Chemin de l'Orme 69280 Marcy l'Etoile, France. Electronic address: junillon.thomas@hotmail.fr.AbstractTetrazolium salts (TTZ) such as 2,3,5-triphenyltetrazolium chloride (TTC) are readily reduced by bacterial populations of various genus. The reduced form of these redox indicators is conspicuously colored allowing a quick and easy detection of growth. The studies are mainly confined to Gram negative bacteria because of an important toxic effect of tetrazolium salts on Gram positive bacteria. Indeed, we observed an important impact of different tetrazolium salts on Listeria monocytogenes growth, curiously limited to an increase in the duration of the lag phase. In this study, we demonstrate that increasing the iron concentration in a medium containing TTC leads to a significant decrease of the lag phase. L. monocytogenes growth was kinetically measured and growth parameters were estimated using the Baranyi model. While lag phase diminution was found to be iron concentration dependent, growth rate was not affected. Addition of iron enables growth of some strains totally inhibited by a 0.4 g/l of TTC and for the other a significant reduction of the latency is observed. The nature of the mechanism resulting in a decrease of the observed lag phase remains unclear. Then, the use of iron supplementation may be proposed to overcome the inhibitory effect of TTC on L. monocytogenes.
• Food microbiology.Food Microbiol.2014 Apr;38:1-5. doi: 10.1016/j.fm.2013.07.005. Epub 2013 Jul 31.
• Tetrazolium salts (TTZ) such as 2,3,5-triphenyltetrazolium chloride (TTC) are readily reduced by bacterial populations of various genus. The reduced form of these redox indicators is conspicuously colored allowing a quick and easy detection of growth. The studies are mainly confined to Gram negative
• PMID 24290619

• Unusual clotting dynamics of plasma supplemented with iron(III).

• Jankun J1, Landeta P1, Pretorius E2, Skrzypczak-Jankun E1, Lipinski B3.Author information 1Urology Research Center, Department of Urology, The University of Toledo - Health Science Campus, Toledo, OH, USA.2Department of Physiology, Faculty of Health Sciences, University of Pretoria, Arcadia, Pretoria, Republic of South Africa.3Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.AbstractIron salts are used in the treatment of iron deficiency anemia. Diabetic patients are frequently anemic and treatment includes administration of iron. Anemic patients on hemodialysis are at an increased risk of thromboembolic coronary events associated with the formation of dense fibrin clots resistant to fibrinolysis. Moreover, in chronic kidney disease patients, high labile plasma iron levels associated with iron supplementation are involved in complications found in dialyzed patients such as myocardial infarction. The aim of the present study was to investigate whether iron treatment is involved in the formation of the fibrin clots. Clotting of citrated plasma supplemented with Fe3+ was investigated by thromboelastometry and electron microscopy. The results revealed that iron modifies coagulation in a complex manner. FeCl3 stock solution underwent gradual chemical modification during storage and altered the coagulation profile over 29 days, suggesting that Fe3+ interacts with both proteins of the coagulation cascade as well as the hydrolytic Fe3+ species. Iron extends clotting of plasma by interacting with proteins of the coagulation cascade. Fe3+ and/or its hydrolytic species interact with fibrinogen and/or fibrin changing their morphology and properties. In general FeCl3 weakens the fibrin clot while at the same time precipitating plasma proteins immediately after application. Fe3+ or its derivatives induced the formation of insoluble coagulums in non-enzymatic reactions including albumin and transferrin. Iron plays a role in coagulation and can precipitate plasma proteins. The formation of coagulums resistant to lysis in non‑enzymatic reactions can increase the risk of thrombosis, and extending clotting of plasma can prolong bleeding.
• International journal of molecular medicine.Int J Mol Med.2014 Feb;33(2):367-72. doi: 10.3892/ijmm.2013.1585. Epub 2013 Dec 11.
• Iron salts are used in the treatment of iron deficiency anemia. Diabetic patients are frequently anemic and treatment includes administration of iron. Anemic patients on hemodialysis are at an increased risk of thromboembolic coronary events associated with the formation of dense fibrin clots resist
• PMID 24337469

和文文献

• Efficacy of a bacterial siderophore, pyoverdine, to supply iron to Solanum lycopersicum plants(PLANT BIOTECHNOLOGY)

• Nagata Takeshi,Oobo Takuro,Aozasa Osamu
• Journal of bioscience and bioengineering 115(6), 686-690, 2013-06
• … Active uptake of ferric iron in microorganisms is based on siderophores. … During iron deficiency, Pseudomonas fluorescens synthesizes siderophores, called pyoverdine, which have a high affinity for ferric iron. … Strategy I plants generally cannot synthesize pyoverdine or take up ferric iron. … We assessed the effect of pyoverdine chelated to ferric iron on iron nutrition in Solanum lycopersicum. …
• NAID 110009614955

• Whey Protein Inhibits Iron Overload-Induced Oxidative Stress in Rats

• KIM Jungmi,PAIK Hyun-Dong,YOON Yoh-Chang,PARK Eunju
• Journal of Nutritional Science and Vitaminology 59(3), 198-205, 2013
• … In this study, we evaluated the effects of whey protein on oxidative stress in rats that were subjected to oxidative stress induced by iron overload. … Thirty male rats were assigned to 3 groups: the control group (regular [50 mg/kg diet] dose of iron+20% casein), iron overload group (high [2,000 mg/kg] dose of iron+20% casein, IO), and whey protein group (high dose of iron+10% casein+10% whey protein, IO+whey). …
• NAID 130003368170

関連リンク

• Dietary Supplement Fact Sheet: Iron — Health Professional Fact Sheet

24 Aug 2007 ... Iron: What is it? Iron, one of the most abundant metals on Earth, is essential to most life forms and to normal human physiology. Iron is an integral part of many proteins and enzymes that maintain good health. In humans, iron ...

関連画像

★リンクテーブル★

「鉄補給」

　　[★]

英

iron supplementation

「iron」

　　[★] 鉄

「ironing」

　　[★]

「supplementation」

　　[★]

• n.

• 補給、補充

関

anaplerotic、recruit、recruitment、replenish、replenishment、supplement、supplementary、supply

「ironed」

　　[★]

「irons」

　　[★]

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