関: interferons, IFNa2b

WordNet

the 1st letter of the Roman alphabet (同)a
the blood group whose red cells carry the A antigen (同)type_A, group A
sequence of a eukaryotic genes DNA that is not translated into a protein (同)noncoding DNA
a brief introductory passage to a piece of popular music

PrepTutorEJDIC

answer / ampere
arsenicの化学記号

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/12 17:14:25」(JST)

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Interferon alfa 2b is an antiviral drug originally discovered in the laboratory of Charles Weissmann at the University of Zurich, developed at Biogen, and ultimately marketed by Schering-Plough under the tradename Intron-A. It has been used for a wide range of indications, including viral infections and cancers.

This drug is approved around the world for the treatment of chronic hepatitis C, chronic hepatitis B, hairy cell leukemia, chronic myelogenous leukemia, multiple myeloma, follicular lymphoma, carcinoid tumor, and malignant melanoma.

Interferon alfa-2b products^[1]
Product	Manufacturer	Features	Special uses
Alpharona	Pharmaclon
Intron-A/IntronA	Schering-Plough
Realderon	Teva
Reaferon EC	GNC Vector
Reaferon EC-Lipint	Vector-Medica	liposomal
Infagel	Vector-Medica	ointment
Recolin	Vector-Medica
Altevir	Bioprocess subsidiary	liquid, free of HSA
Viferon	Feron	suppository or ointment with vitamins C, E	viral, bacterial, chlamydiosis
Kipferon	Alfarm	combination with IgM, IgA, IgG
Giaferon	A/S Vitafarma
Genferon	Biocad
Grippferon	Firn-M	nasal formulation	influenza
Opthalamoferon	Firn-M	with dimedrol	eye infections
Gerpferon	Firn-M	with acyclovir, lidocaine ointment	herpes

References

^ Dmitrij I. Bairamashvili1 and Mikhail L. Rabinovich2* (2007). "Russia through the prism of the world biopharmaceutical market" (PDF). Biotechnol. J 2.

External links

Product website
Intron-A Summary of Product Characteristics
Nagata S, Taira H, Hall A et al. (Mar 1980). "Synthesis in E. coli of a polypeptide with human leukocyte interferon activity". Nature 284 (5754): 316–20. doi:10.1038/284316a0. PMID 6987533.

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This antineoplastic or immunomodulatory drug article is a stub. You can help Wikipedia by expanding it.

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English Journal

Development of intron length polymorphism markers in genes encoding diketide-CoA synthase and curcumin synthase for discriminating Curcuma species.

Kita T1, Komatsu K2, Zhu S2, Iida O3, Sugimura K4, Kawahara N3, Taguchi H5, Masamura N5, Cai SQ6.
Food chemistry.Food Chem.2016 Mar 1;194:1329-36. doi: 10.1016/j.foodchem.2015.08.034. Epub 2015 Aug 12.
Various Curcuma rhizomes have been used as medicines or spices in Asia since ancient times. It is very difficult to distinguish them morphologically, especially when they are boiled and dried, which causes misidentification leading to a loss of efficacy. We developed a method for discriminating Curc
PMID 26471689

Distinct Expression Patterns of AAV8 Vectors with Broadly Active Promoters from Subretinal Injections of Neonatal Mouse Eyes at Two Different Ages.

Xiong W1, Cepko C2.
Advances in experimental medicine and biology.Adv Exp Med Biol.2016;854:501-7. doi: 10.1007/978-3-319-17121-0_67.
The retinal expression patterns were analyzed following the injection of serotype 8 adeno-associated virus (AAV8) vectors that utilize two broadly active and commonly used sets of transcription regulatory sequences. These include the human cytomegalovirus (CMV) immediate early (IE) enhancer/promoter
PMID 26427452

Single-Molecule Live-Cell Visualization of Pre-mRNA Splicing.

Martin RM1, Rino J1, de Jesus AC1, Carmo-Fonseca M2.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1358:335-50. doi: 10.1007/978-1-4939-3067-8_22.
Microscopy protocols that allow live-cell imaging of molecules and subcellular components tagged with fluorescent conjugates are indispensable in modern biological research. A breakthrough was recently introduced by the development of genetically encoded fluorescent tags that combined with fluoresce
PMID 26463395

Japanese Journal

Novel intron-containing luciferase genes for quantitative analysis of mRNA levels in transient gene expression assays

Hayakawa Hideto,Ogura Rieko,Hiratsuka Kazuyuki
Plant Biotechnology 29(5), 505-509, 2012-12
NAID 40019545377

The mtDNA rps3 locus has been invaded by a group ？ intron in some species of Grosmannia

Rudski Shelly M.,Hausner Georg
Mycoscience 53(6), 471-475, 2012-11
NAID 40019496158

Analysis of an intron intervening the SSU rDNA of Chlorella sp. T-24-5, a photobiont of Paramecium bursaria

HOSHINA Ryo
原生動物学雑誌 45(1・2), 17-27, 2012-11
NAID 40019493793

「A」

Interferon alfa 2b
Clinical data
MedlinePlus	a690006
Pregnancy; category	US: C (Risk not ruled out);
Legal status	UK: Prescription-only (POM); US: ℞-only;
Routes of; administration	Subcutaneous, intramuscular
Identifiers
CAS Registry Number
ATC code	L03AB05
IUPHAR/BPS	8338
DrugBank	DB00105
ChEMBL	CHEMBL1201558
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関: introduction

[1] Dmitrij I. Bairamashvili1 and Mikhail L. Rabinovich2* (2007). "Russia through the prism of the world biopharmaceutical market" (PDF). Biotechnol. J 2.

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案内

案内

intron A