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1. オピオイド系薬剤を用いた癌疼痛の管理：至適鎮痛作用 cancer pain management with opioids optimizing analgesia
2. 癌疼痛の管理：介入的治療 cancer pain management interventional therapies
3. 腰部脊柱管狭窄症：病態生理、臨床的特徴、および診断 lumbar spinal stenosis pathophysiology clinical features and diagnosis
4. 脊髄梗塞：血管の解剖学および病因 spinal cord infarction vascular anatomy and etiologies
5. 腰仙部神経根障害：病態生理、臨床的特徴、および診断 lumbosacral radiculopathy pathophysiology clinical features and diagnosis

English Journal

Imaging spectrum of CNS coccidioidomycosis: prevalence and significance of concurrent brain and spinal disease.

Lammering JC, Iv M, Gupta N, Pandit R, Patel MR.Source1 All authors: Department of Radiology, Santa Clara Valley Medical Center, 751 S Bascom Ave, San Jose, CA 95128.
AJR. American journal of roentgenology.AJR Am J Roentgenol.2013 Jun;200(6):1334-46. doi: 10.2214/AJR.12.9264.
OBJECTIVE. The purpose of this study was to evaluate the prevalence and significance of concurrent coccidioidal brain and intraspinal disease. MATERIALS AND METHODS. We conducted a retrospective imaging review of 23 patients with proven coccidioidal CNS meningitis. RESULTS. All patients had intracra
PMID 23701073

Development of surrogate spinal cords for the evaluation of electrode arrays used in intraspinal implants.

Cheng C, Kmech J, Mushahwar VK, Elias AL.AbstractWe report the development of a surrogate spinal cord for evaluating the mechanical suitability of electrode arrays for intraspinal implants. The mechanical and interfacial properties of candidate materials (including silicone elastomers and gelatin hydrogels) for the surrogate cord were tested. The elastic modulus was characterized using dynamic mechanical analysis, and compared with values of actual human spinal cords from the literature. Forces required to indent the surrogate cords to specified depths were measured to obtain values under static conditions. Importantly, to quantify surface properties in addition to mechanical properties normally considered, interfacial frictional forces were measured by pulling a needle out of each cord at a controlled rate. The measured forces were then compared to those obtained from rat spinal cords. Formaldehyde-crosslinked gelatin, 12 wt% in water, was identified as the most suitable material for the construction of surrogate spinal cords. To demonstrate the utility of surrogate spinal cords in evaluating the behavior of various electrode arrays, cords were implanted with two types of intraspinal electrode arrays (one made of individual microwires and another of microwires anchored with a solid base), and cord deformation under elongation was evaluated. The results demonstrate that the surrogate model simulates the mechanical and interfacial properties of the spinal cord, and enables in vitro screening of intraspinal implants.
IEEE transactions on bio-medical engineering.IEEE Trans Biomed Eng.2013 Jun;60(6):1667-76. doi: 10.1109/TBME.2013.2241061. Epub 2013 Jan 23.
We report the development of a surrogate spinal cord for evaluating the mechanical suitability of electrode arrays for intraspinal implants. The mechanical and interfacial properties of candidate materials (including silicone elastomers and gelatin hydrogels) for the surrogate cord were tested. The
PMID 23358939

Cervical intraspinal microstimulation evokes robust forelimb movements before and after injury.

Sunshine MD, Cho FS, Lockwood DR, Fechko AS, Kasten MR, Moritz CT.SourceDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA, USA.
Journal of neural engineering.J Neural Eng.2013 Jun;10(3):036001. doi: 10.1088/1741-2560/10/3/036001. Epub 2013 Apr 3.
Objective. Intraspinal microstimulation (ISMS) is a promising method for reanimating paralyzed limbs following neurological injury. ISMS within the cervical and lumbar spinal cord is capable of evoking a variety of highly-functional movements prior to injury, but the ability of ISMS to evoke forelim
PMID 23548462

Japanese Journal

症例著明なL4/5椎間関節破壊を伴った脊柱管内囊腫の1例

勢理客ひさし,屋良哲也
整形・災害外科 58(1), 115-118, 2015-01
NAID 40020319429

Surgical Treatment of Intraspinal Angiomatous Meningiomas from a Single Center

WU Liang,YANG Tao,YANG Chenlong,DENG Xiaofeng,FANG Jingyi,XU Yulun
Neurologia medico-chirurgica 55(4), 328-335, 2015
… Intraspinal angiomatous meningiomas (AMs) are rare lesions, and no case series have been reported. … We retrospectively reviewed the data of 12 patients with intraspinal AMs. …
NAID 130005065365