WordNet
- lying between two extremes in time or space or state; "going from sitting to standing without intermediate pushes with the hands"; "intermediate stages in a process"; "intermediate stops on the route"; "an intermediate range plane"
- a substance formed during a chemical process before the desired product is obtained
- of or relating to lymphocytes; "lymphocytic leukemia"
- a neoplasm of lymph tissue that is usually malignant; one of the four major types of cancer
PrepTutorEJDIC
- (程度・距離・時間などにおいて)中間の,中間にある(起こる)
UpToDate Contents
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- 1. 小児および思春期におけるホジキンリンパ腫の概要 overview of hodgkin lymphoma in children and adolescents
- 2. 古典型ホジキンリンパ腫の疫学、病理学的特徴、および診断 epidemiology pathologic features and diagnosis of classical hodgkin lymphoma
- 3. 結節性リンパ球優位型ホジキンリンパ腫の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of nodular lymphocyte predominant hodgkin lymphoma
- 4. 結節性リンパ球優位型ホジキンリンパ腫の治療 treatment of nodular lymphocyte predominant hodgkin lymphoma
- 5. マントル細胞リンパ腫の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of mantle cell lymphoma
English Journal
- Integrated CLL Scoring System, a New and Simple Index to Predict Time to Treatment and Overall Survival in Patients With Chronic Lymphocytic Leukemia.
- Visentin A1, Facco M1, Frezzato F1, Castelli M1, Trimarco V1, Martini V1, Gattazzo C1, Severin F1, Chiodin G1, Martines A2, Bonaldi L2, Gianesello I3, Pagnin E3, Boscaro E3, Piazza F1, Zambello R1, Semenzato G4, Trentin L5.
- Clinical lymphoma, myeloma & leukemia.Clin Lymphoma Myeloma Leuk.2015 Oct;15(10):612-20.e1-5. doi: 10.1016/j.clml.2015.06.001. Epub 2015 Jun 20.
- INTRODUCTION: Several prognostic factors have been identified to predict the outcome of patients with chronic lymphocytic leukemia (CLL), but only a few studies analyzed more markers together.PATIENTS AND METHODS: Taking advantage of a population of 608 patients, we identified the strongest prognost
- PMID 26233718
- Survival variations by country and age for lymphoid and myeloid malignancies in Europe 2000-2007: Results of EUROCARE-5 population-based study.
- De Angelis R1, Minicozzi P2, Sant M2, Dal Maso L3, Brewster DH4, Osca-Gelis G5, Visser O6, Maynadié M7, Marcos-Gragera R8, Troussard X9, Agius D10, Roazzi P11, Meneghini E2, Monnereau A12; EUROCARE-5 Working Group.
- European journal of cancer (Oxford, England : 1990).Eur J Cancer.2015 Sep 6. pii: S0959-8049(15)00778-9. doi: 10.1016/j.ejca.2015.08.003. [Epub ahead of print]
- BACKGROUND: Significant advances in the management of patients with lymphoid and myeloid malignancies entered clinical practice in the early 2000's. The EUROCARE-5 study database provides an opportunity to assess the impact of these changes at the population level by country in Europe. We provide su
- PMID 26421827
- Mantle cell lymphoma: 2015 update on diagnosis, risk-stratification, and clinical management.
- Vose JM1.
- American journal of hematology.Am J Hematol.2015 Aug;90(8):739-45. doi: 10.1002/ajh.24094.
- DISEASE OVERVIEW: Mantle cell lymphoma (MCL) is a non-Hodgkin lymphoma characterized by involvement of the lymph nodes, spleen, blood and bone marrow with a short remission duration to standard therapies and a median overall survival (OS) of 4-5 years.DIAGNOSIS: Diagnosis is based on lymph node, bon
- PMID 26103436
Japanese Journal
- フェレットのリンパ腫の細胞形態学的および免疫組織化学的特徴(病理学)
- 小沼 守,近藤 広孝,小野 貞治,渋谷 久,佐藤 常男
- The journal of veterinary medical science 70(9), 893-898, 2008-09-25
- … れ4例(20%),intermediate-gradeが12例(60%)であった.採取組織量が少なかった2例を除く18例について行った免疫組織化学的検索では,T細胞由来が16例(88.9%),B細胞由来が2例(11.1%)であった.NCI-WF分類と免疫学的表現型とを組み合わせると,low-gradeの4例(多中心型2例,消化器型1例,皮膚型1例)のすべてがdiffuse small lymphocytic lymphomaで,いずれもT細胞由来に分類された.Intermediate-gradeの12 …
- NAID 110006946003
- Hepatitis C Virus Infection in Patients with B-cell Non-Hodgkin's Lymphoma
- MIZOROGI Fumi,HIRAMOTO Jun,NOZATO Akiyo,TAKEKUMA Yoshifusa,NAGAYAMA Kazuo,TANAKA Teruji,TAKAGI Keizo
- Internal medicine 39(2), 112-117, 2000-02-01
- … Objective As a causative role of hepatitis C virus (HC V) in B-cell lymphoproliferative disorders (LPD) has been suggested by several reports, we investigated the prevalence of HCV infection among patients with LPD at our hospital with the aim of clarifying the clinical features and the outcome for HCV antibody-positive patients with non-Hodgkin's lymphoma (NHL). …
- NAID 10013261429
- Intermediate lymphocytic lymphoma massively involving the gastrointestinal tract
- TSUTSUMI Yutaka,OSAMURA Yoshiyuki R.,MAKUUCHI Hiroyasu
- Pathology international 46(5), 380-383, 1996-05
- NAID 10008333925
Related Links
- 1. J Clin Oncol. 1993 Apr;11(4):802-111. Intermediate lymphocytic lymphoma: clinical and pathologic features of a recently characterized subtype of non-Hodgkin's lymphoma. Shivdasani RA, Hess JL, Skarin AT, Pinkus GS. Division ...
- 回虫を伴った,Weisenburgerら<SUP>1)</SUP>の言うA follicular variant of intermediate lymphocytic lymphoma (mantle-zone lymphoma) で肝に原発した1症例を報告した.腹部超音波像では石灰化を伴った,高輝度な腫瘍として描出された ...
Related Pictures
★リンクテーブル★
| リンク元 | 「マントル細胞リンパ腫」「中間型リンパ球性リンパ腫」 |
| 関連記事 | 「intermediate」「lymphocytic lymphoma」「lymphocytic」「intermedia」 |
「マントル細胞リンパ腫」
- 英
- mantle-cell lymphoma, mantle cell lymphoma
- 関
- 暗殻細胞リンパ腫、中間型リンパ球性リンパ腫 intermediate lymphocytic lymphoma、外套層状リンパ腫 mantle zone lymphoma
- 悪性リンパ腫
概念
- 成熟B細胞腫瘍の一種
- 染色体転座t(11;14)(q13;q32)が認められる。
- CD5を発現する。CyclinD1遺伝子の過剰発現は高頻度
- 別名：MCL has been previously referred to as intermediate lymphocytic lymphoma, mantle zone lymphoma, centrocytic lymphoma, and lymphocytic lymphoma of intermediate differentiation
発生母地
- Most MCL cases are postulated to derive from naïve pre-germinal center B cells of the mantle zone, while a subset of MCL may originate from marginal zone or peripheral blood memory B cells.
講義ノート
- 中リンパ球
- 核クロマチンは均一に濃縮し、核小体は不明瞭。核は軽度の不整とくびれ有り(convoluted cell)
- マントル細胞リンパ腫は慢性リンパ性白血病と同様にCD5(+)のB細胞であるが、予後は大きく異なり、化学療法のCHOPが奏効しにくく、寛解率は10-40%。
細胞表面マーカー
| sIg | ＋ | 細胞表面のIg |
| CD5 | ＋ | 胸腺細胞、T細胞、B細胞のサブセット |
| CD10 | － | B細胞やT細胞前駆体。骨髄間質細胞(bone marrow stromal cell) 。Zinc metalloproteinase, marker for pre-B acute lymphatic leukemia (ALL) |
| CD19 | ＋ | B-cell co-receptor: CD19+CD21+CD81 |
| cyclin | ＋ | サイクリン依存性キナーゼ(CDK)の活性化サブユニット |
| *Bリンパ球のマーカーとされているもの CD10,CD19,CD20 | ||
発生母地
- The malignant cell in mantle cell lymphoma is postulated to derive from a naive B-cell of follicle mantle or germinal center origin. This cell is distinct from both the recirculating B-cell of B-CLL/SLL and the later centrocyte of follicular lymphoma
-mantle-cell lymphoma
「中間型リンパ球性リンパ腫」
「intermediate」
- n.
- adj.
- 中間の、中間部の、中等の、間性の
- 関
- halfway、intermediary、intermediary body、intermedius、intersex、interstitial、interzonal、middle、moderate
「lymphocytic lymphoma」
- 関
- B-cell chronic lymphocytic leukemia、chronic B-cell leukemia、chronic lymphocytic leukemia、small lymphocytic lymphoma、small-cell lymphoma
「lymphocytic」
- adj.
- リンパ球性の、リンパ性の、リンパ球系の
「intermedia」