interleukin-6

出典: meddic

IL-6

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/02/09 22:54:29」(JST)

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英文文献

  • Pregnane x receptor modulates the inflammatory response in primary cultures of hepatocytes.
  • Sun M1, Cui W1, Woody SK1, Staudinger JL2.
  • Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2015 Mar;43(3):335-43. doi: 10.1124/dmd.114.062307. Epub 2014 Dec 19.
  • Bacterial sepsis is characterized by a rapid increase in the expression of inflammatory mediators to initiate the acute phase response in liver. Inflammatory mediator release is counterbalanced by the coordinated expression of anti-inflammatory molecules such as interleukin 1 receptor antagonist (IL
  • PMID 25527709
  • Inhibition of IL-6/STAT3 axis and targeting Axl and Tyro3 receptor tyrosine kinases by apigenin circumvent taxol resistance in ovarian cancer cells.
  • Suh YA1, Jo SY1, Lee HY2, Lee C2.
  • International journal of oncology.Int J Oncol.2015 Mar;46(3):1405-11. doi: 10.3892/ijo.2014.2808. Epub 2014 Dec 23.
  • Ovarian cancer is the number one cause of death from gynaecological malignancy. Platinum-based and taxol-based chemotherapy has been used as a standard therapy, but intrinsic and acquired resistance to chemotherapy is a major obstacle to treat the disease. In the present study, we found that in the
  • PMID 25544427
  • Association of inflammatory biomarkers with depressive symptoms and cognitive decline in a community-dwelling healthy older sample: A 3-year follow-up study.
  • Matsushima J1, Kawashima T2, Nabeta H2, Imamura Y3, Watanabe I4, Mizoguchi Y2, Kojima N5, Yamada S6, Monji A7.
  • Journal of affective disorders.J Affect Disord.2015 Mar 1;173:9-14. doi: 10.1016/j.jad.2014.10.030. Epub 2014 Oct 22.
  • BACKGROUND: The relationship between the pathophysiology of dementia and neuroinflammation is well-known. The number of reports stating that depression is a risk factor for dementia has recently been increasing. These epidemiological findings suggest the possibility that both depression and dementia
  • PMID 25462389

和文文献

関連リンク

Function [edit] IL-6 is an important mediator of fever and of the acute phase response. It is capable of crossing the blood-brain barrier [3] and initiating synthesis of PGE 2 in the hypothalamus, thereby changing the body's temperature ...
IL-6(インターロイキン(Interleukin)-6)はT細胞やマクロファージ等の細胞により産生されるレクチンであり、液性免疫を制御するサイトカインの一つである。IL-6は1986年に相補的DNA(cDNA)がクローニングされ [1] 、以降IL-6は種々の生理現象や ...

関連画像

interleukin 6 il 6 acts as both a pro IL-6 / Interleukin 6 & ReceptorInterleukin-6, Molecular Model PhotographInterleukin-6Interleukin-6 expression in the central interleukin 6


★リンクテーブル★
リンク元IL-6
拡張検索interleukin-6 receptor」「interleukin-6 receptor alpha subunit
関連記事interleukin」「interleukins

IL-6」

  [★]

interleukin-6
B細胞刺激因子2 B cell stimulating factor 2 BSF-2
サイトカイン

産生細胞

機能

  • 液性免疫に関わる。

IL-6の多彩な機能

肝細胞 APP産生
メサンギウム細胞 増殖
神経細胞 分化
NK細胞 活性化
骨髄腫細胞 増殖
B細胞 抗体産生
T細胞 キラーT細胞IL-2産生
巨核球 血小板増多
造骨系幹細胞 分化

受容体

  • CD126, CD130

臨床関連



interleukin-6 receptor」

  [★]

IL-6 receptor、IL6 receptor


interleukin-6 receptor alpha subunit」

  [★]


interleukin」

  [★] インターロイキン IL

WordNet   license wordnet

「any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system」

interleukins」

  [★] インターロイキン IL




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