interleukin-23 subunit p19

出典: meddic


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  • Identification of IL-23p19 as an endothelial proinflammatory peptide that promotes gp130-STAT3 signaling.
  • Espígol-Frigolé G1, Planas-Rigol E2, Ohnuki H3, Salvucci O3, Kwak H3, Ravichandran S4, Luke B4, Cid MC5, Tosato G6.
  • Science signaling.Sci Signal.2016 Mar 15;9(419):ra28. doi: 10.1126/scisignal.aad2357.
  • Interleukin-23 (IL-23), a heterodimeric cytokine composed of the unique p19 peptide (IL-23p19) and a peptide called IL-12p40, which is shared with IL-12, is implicated in Crohn's disease, rheumatoid arthritis, psoriasis, and other immune-mediated inflammatory diseases. Endothelial cells produce the
  • PMID 26980441
  • Neutralization of IL-23 depresses experimental ocular neovascularization.
  • Cai Y1, Tan W2, Shen X1, Zhu Y1, Gao Y1, Sui A1, Lu Q1, Zhong Y3, Xie B4.
  • Experimental eye research.Exp Eye Res.2016 Mar 14;146:242-251. doi: 10.1016/j.exer.2016.02.008. [Epub ahead of print]
  • Interleukin-23 (IL-23) is a heterodimeric cytokine that consists of p19, a novel subunit, and p40, which is shared by IL-12. IL-23 has been demonstrated to play an important role in autoimmunity and tumor growth. However, the role of IL-23 in ocular neovascularization (NV) diseases remains unclear.
  • PMID 26980350
  • Interleukin 23 regulates the functions of human decidual immune cells during early pregnancy.
  • Cai JY1, Li MJ2.
  • Biochemical and biophysical research communications.Biochem Biophys Res Commun.2016 Jan 15;469(3):340-4. doi: 10.1016/j.bbrc.2015.11.118. Epub 2015 Nov 30.
  • BACKGROUND: This study investigated the effects of interleukin 23 (IL-23) on the production of cytokines (IL-1, IL-4, IL-10, and IL-17), the differentiation of Treg/Th17 and STAT3 (i.e., signal transducer and activator of transcription 3) in human decidual immune cells (DICs) during early pregnancy.
  • PMID 26657845


  • Molecular Cloning of the Swine Interleukin-23 Subunit p19 and of its Receptor Components Interleukin-23Rα and -12Rβ1
  • The journal of veterinary medical science 74(3), 367-372, 2012-03
  • NAID 40019249456
  • Molecular Cloning of the Swine Interleukin-23 Subunit p19 and of its Receptor Components Interleukin-23R α and -12Rβ1


... alpha subunit p19, interleukin-23 subunit p19, interleukin-six, G-CSF related factor GeneRIFs: Gene References Into Functions IL-23 mediates the differentiation of Th17 and Treg cells and the production of associated ...
Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. ... Gene ID: 83430, updated on 20-Aug-2016 Summary Other designations IL-23 subunit alpha, IL-23-A, IL-23p19, interleukin-23 subunit p19


Immunohistochemistry-Paraffin: IL23 P19 IL23A (interleukin 23, alpha subunit p19)IL23A (interleukin 23, alpha subunit p19)interleukin 23 alpha subunit p19IHC) #2 for IL23A antibody Anti-IL-23 p19 Interleukin-18 Receptor Alpha Subunit




interleukin-23 subunit p19


  [★] インターロイキン IL

WordNet   license wordnet

「any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system」





  [★] インターロイキン IL