WordNet

swelling from excessive accumulation of watery fluid in cells, tissues, or serous cavities (同)oedema, hydrops, dropsy
located between cells

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Geraniol Ameliorates TNBS-induced Colitis: Involvement of Wnt/β-catenin, p38MAPK, NFκB, and PPARγ Signaling Pathways.

Soubh AA1, Abdallah DM2, El-Abhar HS3.
Life sciences.Life Sci.2015 Jul 9. pii: S0024-3205(15)00356-2. doi: 10.1016/j.lfs.2015.07.004. [Epub ahead of print]
AIMS: Geraniol, a natural component of plant essential oils, exhibits potent chemopreventive effects in colon; however, its possible role/mechanisms in experimental colitis has not been elucidated, which is the aim of this study.MAIN METHODS: To fulfill this goal, rats were treated for 11 days with
PMID 26165751

Exendin-4-loaded PLGA microspheres relieve cerebral ischemia/reperfusion injury and neurologic deficits through long-lasting bioactivity-mediated phosphorylated Akt/eNOS signaling in rats.

Chien CT1, Jou MJ2, Cheng TY3, Yang CH4, Yu TY5, Li PC5.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.J Cereb Blood Flow Metab.2015 Jun 10. doi: 10.1038/jcbfm.2015.126. [Epub ahead of print]
Glucagon-like peptide-1 (GLP-1) receptor activation in the brain provides neuroprotection. Exendin-4 (Ex-4), a GLP-1 analog, has seen limited clinical usage because of its short half-life. We developed long-lasting Ex-4-loaded poly(D,L-lactide-co-glycolide) microspheres (PEx-4) and explored its neur
PMID 26058696

Epidermal barrier abnormalities in exfoliative ichthyosis with a novel homozygous loss-of-function mutation in CSTA.

Moosbrugger-Martinz V1, Jalili A2, Schossig AS3, Jahn-Bassler K2, Zschocke J3, Schmuth M1, Stingl G2, Eckl KM4, Hennies HC4, Gruber R1,4.
The British journal of dermatology.Br J Dermatol.2015 Jun;172(6):1628-32. doi: 10.1111/bjd.13545. Epub 2015 Mar 18.
Autosomal recessive exfoliative ichthyosis (AREI) results from mutations in CSTA, encoding cysteine protease inhibitor A (cystatin A). We present a 25-year-old man from Iran with consanguineous parents, who presented with congenital erythroderma, hyperhidrosis and diffuse hyperkeratosis with coarse
PMID 25400170

堀貞夫
東京女子医科大学雑誌 82(5), 302-308, 2012-10-25
就任中に女子医大創立100年を迎え、また眼科学教室も50周年を迎えた。そんな環境の中で教室を主宰できたのは幸運この上もないことと感じている。医局員の一人ひとりがそれぞれの個性を持って教室作りをしてくれた。その協力の上に立った結果で、深甚の謝意を表したい。,2年前の日本眼科学会総会で特別講演を担当し、「糖尿病網膜症の治療戦略」という総説を講演した。特別講演の演者は日本眼科学会賞という名誉ある賞を受け …
NAID 110009557337

Induction of aldose reductase expression and reduction of sorbitol dehydrogenase expression by methylmercury in cultured human brain microvascular pericytes

HIRATA Akishige,HIROOKA Takashi,YAMAMOTO Chika,KAJI Toshiyuki
日本毒性学会学術年会 39.2(0), AP-56, 2012
… The purpose of the present study was to investigate the molecular mechanism of cytotoxic edema from the viewpoint of the toxic effects of methylmercury on the polyol pathway in brain microvascular endothelial cells and pericytes. … These results suggest that methylmercury cause a cytotoxic edematous change in pericytes by swelling due to elevation of the intercellular osmotic pressure and water content, which would be caused by excess accumulation of sorbitol via induction of AR expression and reduction of SDH expression. …
NAID 130005009217

Gastric mucosal changes induced by polyethylene glycol 400 administered by gavage in rats

Ueda Yoshihide,Tsuboi Masaru,Ota Yasufumi [他],MAKITA Maki,AOSHIMA Takuya,NAKAJIMA Madoka,NARAMA Isao
Journal of toxicological sciences 36(6), 811-815, 2011-12-01
… The changes consisted of infiltration of eosinophils and globule leukocytes, increased in the height of the entire mucosal layer, elongation of the surface mucous epithelial and mucous neck cell layers with increased intracellular mucous in the glandular stomach, and the spongiosis (intercellular edema) of the squamous epithelium in the forestomach. …
NAID 10030037050