化膿性脊椎炎
WordNet
- of or relating to infection; "infectious hospital"; "infectious disease"
- caused by infection or capable of causing infection; "viruses and other infective agents"; "a carrier remains infective without himself showing signs of the disease" (同)infective
- easily spread; "fear is exceedingly infectious; children catch it from their elders"- Bertrand Russell
- inflammation of a spinal joint; characterized by pain and stiffness
PrepTutorEJDIC
- (病気が)伝染する,伝染性の / (影響などが)感化しやすい,うつりやすい
UpToDate Contents
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- 1. 成人の体軸性脊椎関節炎（強直性脊椎炎およびX線画像に変化が認められない体軸性脊椎関節炎）の治療treatment of axial spondyloarthritis ankylosing spondylitis and nonradiographic axial spondyloarthritis in adults [show details]
… of death in patients with AS were infections, cancer, and diseases of the respiratory and cardiovascular systems . Management recommendations for ankylosing spondylitis (AS) and non-radiographic axial …
- 2. 脊髄に影響を与える疾患disorders affecting the spinal cord [show details]
… infarction. Tuberculosis can produce a myelopathy by different mechanisms. Infection of the vertebral body leads to tuberculous spondylitis or Pott disease, which can lead to secondary cord compression. These …
- 3. AAアミロイドーシスの原因と診断およびリウマチ性疾患との関連性causes and diagnosis of aa amyloidosis and relation to rheumatic diseases [show details]
…arthritis (RA), juvenile idiopathic arthritis, ankylosing spondylitis (AS), inflammatory bowel disease, familial periodic fever syndromes, chronic infections, and certain neoplasms The major causes and …
- 4. 成人における慢性膝痛の放射線評価radiologic evaluation of the chronically painful knee in adults [show details]
… Chronic infection may occur in the knee joint or in the juxtaarticular bone. Mycobacterial and fungal infections in either site may be indolent… reactive arthritis (formerly Reiter syndrome), and peripheral arthritis in patients with ankylosing spondylitis (AS). Less common arthritides that cause chronic knee pain, such as neuropathic arthropathy …
- 5. 成人の股関節痛の画像診断imaging evaluation of the painful hip in adults [show details]
… Infectious fasciitis – MRI is very sensitive for evaluation of fascial inflammation, evaluating the extent of infection and the presence of abscess… inflammatory arthritis such as rheumatoid arthritis (RA) and ankylosing spondylitis (AS),…
English Journal
- Epidemiology of uveitis in a US population-based study.
- González MM1, Solano MM1, Porco TC2, Oldenburg CE1,2,3, Acharya NR1,2, Lin SC1, Chan MF4,5.
- Journal of ophthalmic inflammation and infection.J Ophthalmic Inflamm Infect.2018 Apr 17;8(1):6. doi: 10.1186/s12348-018-0148-5.
- PMID 29666980
- Perineural Spread along Spinal and Obturator Nerves in Primary Vaginal Carcinoma: A Case Report.
- Song EJ, Park JS, Ryu KN, Park SY, Jin W.
- World neurosurgery.World Neurosurg.2018 Apr 13. pii: S1878-8750(18)30746-0. doi: 10.1016/j.wneu.2018.04.030. [Epub ahead of print]
- BACKGROUND: Perineural spread is not uncommon feature in carcinoma of the head and neck. On the contrary, perineural spread in pelvic malignancies has been rarely reported. This report is the first report about perineural spread of obturator nerve and lumbosacral plexus from primary vaginal cancer.C
- PMID 29660549
Japanese Journal
- 村松 匠,山岡 邦宏
- 臨床リウマチ 33(3), 181-188, 2021
- <p> 関節リウマチ（RA）の病態の中心となっているのがサイトカインである．既存の抗リウマチ薬に加えて，サイトカインなどを標的とした生物学的製剤を用いることで，RAは寛解が達成できる疾患となってきた．さらに，ヤヌスキナーゼ（JAK）阻害薬がRAの治療の選択肢となり，既存治療に抵抗性のRAに対しても効果が期待できるようになった．加えて，炎症性腸疾患やコロナウイルス感染症2019（COVI …
- NAID 130008106853
- Tuberculous Spondylitis in a Woman without Pulmonary Lesions
- Morita Shinichi,Takada Toshinori,Ohashi Kazumasa,Terai Shuji
- Internal Medicine 60(13), 2157-2158, 2021
- NAID 130008060462
- Spontaneous Pyogenic Spondylitis and Possible Infective Endocarditis Caused by <i>Aggregatibacter actinomycetemcomitans</i>
- Yukihira Naoko,Hori Hiroshi,Yamashita Takeshi,Kawamura Ai,Fukuchi Takahiko,Sugawara Hitoshi
- Internal Medicine 60(10), 1621-1625, 2021
- … <p><i>Aggregatibacter actinomycetemcomitans</i>, an etiological agent associated with periodontitis, endocarditis, and other infections, has rarely been implicated in spondylitis. … A 70-year-old man with aortic valve replacement presented with a 4-month history of lower back pain and was diagnosed with spondylitis. … Concurrent infective endocarditis (IE) was probable considering the infectious organism and the patients' …
- NAID 130008038552
Related Links
- Imaging techniques Conventional radiographs remain the initial screening procedure when infectious spondylitis is suspected. Compared to magnetic resonance imaging (MRI) and radionuclide scans, radiographs are relatively ...
- 1. Radiologe. 1996 Oct;36(10):795-804. [Infectious spondylitis in adults]. [Article in German] Vorbeck F, Morscher M, Ba-Ssalamah A, Imhof H. In adults, infectious spondylitis is a rare but severe disease, caused by a bacterial ...
★リンクテーブル★
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- 英
- pyogenic spondylitis (SOR), vertebral osteomyelitis, infectious spondylitis
- ラ
- spondylitis osteomyelitica
疫学
- 中・高年齢者に多い。
- 易感染性免疫宿主(糖尿病など)の症例が増加してきている。
病原体
- 黄色ブドウ球菌がほとんど。グラム陰性桿菌、MRSAもありうる。(黄色ブドウ球菌と大腸菌が多い。易感染性宿主やMRSAやその他弱毒菌が真菌が病原体となりうる。(SOR.201))
- 好発部位は胸椎・腰椎(下位胸椎から腰仙椎部)。頚椎は希
病態＆病態生理
- 骨盤や腹部の感染病巣の細菌が椎骨静脈叢を通じて椎体終板に達して発症
- 椎体軟骨終板の静脈に発生した病巣が椎体全体に広がり膿瘍を形成する。この膿瘍や圧潰した骨片の脊柱管への突出、圧迫により神経障害をきたすことがある。X線上は椎体軟骨終板の破壊により椎間板の栄養が断たれ、椎間板が圧潰するため椎間腔の狭小化をきたす。さらに椎体の破壊・圧潰・後弯変形をきたす。(CBT QB vol2 p.578)
病型と症状
- 急性：発熱、激痛
- 亜急性：急性より穏やか
- 慢性：慢性疼痛
症状
検査
- 初期にはX線では異常は見られない。発症後2-3週間で、椎間板腔狭小化、椎体終板の骨破壊
- 早期診断にはMRIが有効。T1で低信号、T2で高信号
単純X線検査
- 発症3-4週：椎間腔狭小、椎体辺縁の不整化。骨破壊
- 発症3-5ヶ月：骨棘形成、骨硬化像
鑑別診断
- 結核性脊椎炎：X線像で骨破壊部に腐骨が見られる。造影MRIで辺縁増強効果。
- 癌の脊椎転移：椎弓根部が不鮮明
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- 関
- communicability、communicable、contagious、epidemic、infectiosity、infectiousness、infective、infectivity、transmissibility、transmissible