- 同
- iNOS
WordNet
- used to express refusal or denial or disagreement etc or especially to emphasize a negative statement; "no, you are wrong"
- a negative; "his no was loud and clear"
- referring to the degree to which a certain quality is present; "he was no heavier than a child" (同)no more
- not in any degree or manner; not at all; "he is no better today"
- quantifier; used with either mass nouns or plural count nouns for indicating a complete or almost complete lack or zero quantity of; "we have no bananas"; "no eggs left and no money to buy any"; "have you no decency?"; "did it with no help"; "Ill get you there in no time"
- the 14th letter of the Roman alphabet (同)n
PrepTutorEJDIC
- 《名詞の前に置いて》『一つも』(『一人も,少しも』)・・・『ない』 / 《補語につけて》『決して・・・でない』 / 《省略文で》・・・なし;・・・お断り / 《話》少ししか(あまり)・・・ない / (肯定の問いに対して)『いいえ』;(否定の問いに対して)はい,ええ / 《not, norの前に挿入して》『いや』,否 / 《形容詞の前に置その形容詞を否定して》…どころではない / 《比較級の前に置いて》ちっとも…でない,…と全く同じ / 《… or no の形で》…であってもなくても / 《驚き・困惑・不信などを表して》とんでもない / 《単数形で》『拒否』,「『いいえ』」という返事 / 《複数形で》反対[投]票
- nitrogenの化学記号
UpToDate Contents
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- 1. 呼気中一酸化窒素の分析および適用 exhaled nitric oxide analysis and applications
- 2. 心不全における一酸化窒素、その他のホルモン、サイトカイン、およびケモカイン nitric oxide other hormones cytokines and chemokines in heart failure
- 3. 一酸化窒素と腎臓 nitric oxide and the kidney
- 4. 虚血性脳卒中の病態生理 pathophysiology of ischemic stroke
- 5. デュシェンヌ型およびベッカー型筋ジストロフィーの臨床的特徴および診断 clinical features and diagnosis of duchenne and becker muscular dystrophy
English Journal
- Increased exhaled nitric oxide and its oxidation metabolism in eosinophilic chronic rhinosinusitis.
- Takeno S, Taruya T, Ueda T, Noda N, Hirakawa K.SourceDepartment of Otolaryngology, Head and Neck Surgery, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan. Electronic address: takeno@hiroshima-u.ac.jp.
- Auris, nasus, larynx.Auris Nasus Larynx.2013 Oct;40(5):458-64. doi: 10.1016/j.anl.2013.02.001. Epub 2013 Mar 13.
- OBJECTIVE: Monitoring of fractional concentrations of exhaled nitric oxide (FeNO) has become a reliable marker of inflammation in human nose and paranasal sinuses. However, it is still unknown to what extent nasal NO levels contribute to the pathology of chronic rhinosinusitis (CRS). In the present
- PMID 23489830
- Asymmetric dimethylarginine regulates the lipopolysaccharide-induced nitric oxide production in macrophages by suppressing the activation of NF-kappaB and iNOS expression.
- Pekarova M, Kubala L, Martiskova H, Bino L, Twarogova M, Klinke A, Rudolph TK, Kuchtova Z, Kolarova H, Ambrozova G, Kuchta R, Kadlec J, Lojek A.SourceInstitute of Biophysics, Academy of Sciences of the Czech Republic, Kralovopolska 135, 612 65 Brno, Czech Republic. Electronic address: pekarovam@ibp.cz.
- European journal of pharmacology.Eur J Pharmacol.2013 Aug 5;713(1-3):68-77. doi: 10.1016/j.ejphar.2013.05.001. Epub 2013 May 9.
- Two major effector systems are frequently implicated in the immune and endothelial cell alternations associated with inflammation. They include the enhanced production of reactive oxygen species and diminished bioavailability of nitric oxide (NO). Importantly, these processes can be regulated by end
- PMID 23665490
- Activation of cultured astrocytes by amphotericin B: Stimulation of NO and cytokines production and changes in neurotrophic factors production.
- Motoyoshi-Yamashiro A, Tamura M, Moriyama M, Takano K, Kawabe K, Nakajima H, Katoh-Semba R, Furuichi T, Nakamura Y.SourceLaboratory of Integrative Physiology in Veterinary Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Japan.
- Neurochemistry international.Neurochem Int.2013 Aug;63(2):93-100. doi: 10.1016/j.neuint.2013.05.007. Epub 2013 May 28.
- Amphotericin B (AmB) is a polyene antibiotic and reported to be one of a few reagents having therapeutic effects on prion diseases, such as the delay in the appearing of the clinical signs and the prolongation of the survival time. In prion diseases, glial cells have been suggested to play important
- PMID 23727061
Japanese Journal
- 一酸化窒素合成酵素と心不全 : 遺伝子改変マウスからの教訓
- 柴田 清子,下川 宏明,柳原 延章 [他],尾辻 豊,筒井 正人
- 産業医科大学雑誌 35(2), 147-158, 2013-06-01
- … 一酸化窒素(NO)合成酵素(NOS)には,神経型,誘導型,内皮型の3種類のNOSアイソフォームが存在する.ヒト心臓には,すべてのNOSsが発現している.従来,心不全におけるNOSsの役割が,NOS阻害薬を用いて研究されてきた.さらに,近年では,遺伝子改変動物が実験に使用されるようになり,ヒト心不全におけるNOSsの役割の理解に重要な示唆を与えている.我々は,NOSアイソフォームを欠損させたNOS遺伝子改変マウスを用いて,その心臓の構造と …
- NAID 110009615291
- Dual Role of Nitric Oxide in Pancreatic β-Cells
- Kurohane Kaneko Yukiko,Ishikawa Tomohisa
- Journal of Pharmacological Sciences, 295-300, 2013
- … An involvement of inducible nitric oxide (NO) synthase (NOS) in pancreatic β-cell degeneration during the process of type 1 diabetes has been well discussed. … the presence of NOS1 and NOS3 in pancreatic β-cells and the effects of low-concentration NO, which is assumed to be derived from cNOS, on β-cell functions have been reported. … However, the roles of cNOS-derived NO in β-cells are still under debate. …
- NAID 130003382623
- Xanthoceraside Inhibits Pro-inflammatory Cytokine Expression in Aβ₂₅₋₃₅/IFN-γ-Stimulated Microglia Through the TLR2 Receptor, MyD88, Nuclear Factor-κB, and Mitogen-Activated Protein Kinase Signaling Pathways
- Qi Yue,Zou Li-Bo,Wang Li-Hua [他],Jin Ge,Pan Jin-Jin,Chi Tian-Yan,Ji Xue-Fei
- Journal of Pharmacological Sciences 122(4), 305-317, 2013
- … Our results indicated that xanthoceraside (0.01 and 0.1 μM) significantly inhibited the release of nitric oxide (NO) and pro-inflammatory cytokines interleukin-1β and tumor necrosis factor-α in a concentration-dependent manner. … Reverse transcriptase–polymerase chain reaction and western blotting analyses showed that xanthoceraside decreased the Aβ25–35/IFN-γ–induced production of cyclooxygenase-2 and inducible NO synthase. …
- NAID 130003362723
Related Links
- Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. ... Gene ID: 18126, updated on 4-Aug-2013 Summary Other designations MAC-NOS, NOS type II, inducible NO ...
- 1. J Exp Biol. 1999 Mar;202(Pt 6):645-53. Inducible NO synthase: role in cellular signalling. Beck KF, Eberhardt W, Frank S, Huwiler A, Messmer UK, Mühl H, Pfeilschifter J. Zentrum der Pharmakologie, Klinikum der Johann ...
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★リンクテーブル★
| リンク元 | 「誘導型NO合成酵素」 |
| 関連記事 | 「synthase」「inducible」「N」「NO synthase」「NO」 |
「誘導型NO合成酵素」
- 英
- inducible NO synthase inducible NO-synthase inducible nitric oxide synthase, inducible NOS iNOS
- 同
- 誘導型一酸化窒素合成酵素、誘導型NOS
- 関
- NO
分類 (BPT.50)
- Type I：nNOS：constitutively expressed
- Type II：iNOS：present in macrophages and endothelial cells. also present in many other cells types, including hepatocytes, cardiac myocytes, and respiratory epithelium.
- Type III：eNOS：constitutively expressed. endothelium
産生
- 炎症性サイトカインにより発現が誘導される：IL-1, INF, INF-γ, bacterial endotoxin。(BPT.50)
「synthase」
- n.
「inducible」
- adj.
- 誘導性の、誘発性の、誘導型の、誘導可能な
「N」
- アスパラギン asparagine
- 窒素(原子、分子)