関: indometacin、indometacin farnesil、indomethacin、indomethacin farnesil、indomethacin sodium

WordNet

a nonsteroidal anti-inflammatory drug (trade name Indocin) (同)Indocin
a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11

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Honokiol improves learning and memory impairments induced by scopolamine in mice.

Xian YF1, Ip SP2, Mao QQ1, Su ZR3, Chen JN3, Lai XP3, Lin ZX4.
European journal of pharmacology.Eur J Pharmacol.2015 Aug 5;760:88-95. doi: 10.1016/j.ejphar.2015.04.013. Epub 2015 Apr 23.
Honokiol, a lignan isolated from the bark of Magnolia officinalis, has been reported to ameliorate the learning and memory impairments in senesed (SAMP8) mice. However, whether honokiol could improve scopolamine (SCOP)-induced learning and memory deficits in mice is still unknown. In this study, we
PMID 25912802

Gastroprotective effect of andrographolide sodium bisulfite against indomethacin-induced gastric ulceration in rats.

Liu YH1, Zhang ZB1, Zheng YF1, Chen HM1, Yu XT2, Chen XY1, Zhang X1, Xie JH3, Su ZQ1, Feng XX1, Zeng HF4, Su ZR5.
International immunopharmacology.Int Immunopharmacol.2015 Jun;26(2):384-91. doi: 10.1016/j.intimp.2015.04.025. Epub 2015 Apr 24.
Andrographolide sodium bisulfite (ASB), a water-soluble sulfonate of andrographolide has been shown to possess anti-inflammatory, antipyretic and analgesic activities. However, there is no report on the gastroprotective effect of ASB against indomethacin-induced gastric ulcer. Here we investigated t
PMID 25916678

5-HT1D receptor inhibits renal sympathetic neurotransmission by nitric oxide pathway in anesthetized rats.

García-Pedraza JÁ1, García M1, Martín ML1, Morán A2.
Vascular pharmacology.Vascul Pharmacol.2015 May 21. pii: S1537-1891(15)00105-6. doi: 10.1016/j.vph.2015.05.003. [Epub ahead of print]
Although serotonin has been shown to inhibit peripheral sympathetic outflow, serotonin regulation on renal sympathetic outflow has not yet been elucidated. This study investigated which 5-HT receptor subtypes are involved. Wistar rats were anesthetized (sodium pentobarbital; 60mg/kg, i.p.), and prep
PMID 26003124

Ｉｎｄｏｍｅｔａｃｉｎ　ｆａｒｎｅｓｉｌのヒトＢ細胞免疫グロブリン産生に対する抑制作用　　特にｂｕｃｉｌｌａｍｉｎｅ・注射金剤との相互作用:―特にbucillamine・注射金剤との相互作用―

広畑俊成,柳田たみ子
炎症 17(6), 565-571, 1997
… Indometacin farnesil (IMF) is a prodrug of indomethacin (IND) designed to reduce the occurrence of side-effects by esterification of the carboxyl group on IND with farnesol (FAR) . … Of note, IMF, but not IND, showed additive suppressive effects on the B cell Ig production in the presence of either intramolecular disulfide form of bucillamine (SA-981) or gold sodium thiomalate. …
NAID 130003709524