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1. 化学療法誘発性悪心および嘔吐の病態生理および予測pathophysiology and prediction of chemotherapy induced nausea and vomiting [show details]
…previously called the "vomiting center") and two areas in the dorsal brainstem called the nucleus tractus solitarius (NTS) and area postrema (AP) . The CPG is an anatomically indistinct collection of receptor…
2. 頭蓋顔面痛の概要overview of craniofacial pain [show details]
…overlap of cranial nerves V, VII, IX, X, which converge on the spinal trigeminal nucleus and the tractus solitarius. The mechanisms of neuropathic pain are complex. A nerve injury can induce peripheral …
3. 換気調節control of ventilation [show details]
…body cells. Impulses from the carotid bodies travel through the IX cranial nerve to the nucleus tractus solitarius (NTS), where excitatory neurotransmitters are released that result in increased ventilation…
4. 肥満への遺伝的影響と病態生理genetic contribution and pathophysiology of obesity [show details]
…tract and oropharynx is neurally transmitted to the hindbrain and processed in the nucleus of the tractus solitarius. Leptin and possibly glucose and amino acids reach the brain by transport across the blood-brain…
5. 成人におけるうつ病：ニューロモデュレーション治療の概要depression in adults overview of neuromodulation procedures [show details]
…system structures that may be involved in depression, such as the locus coeruleus and the nucleus tractus solitarius . Low field magnetic stimulation is an investigational procedure for treatment resistant…

English Journal

Binge-like palatable food intake in rats reduces preproglucagon in the nucleus tractus solitarius.

Mukherjee A, Hum A, Gustafson TJ, Mietlicki-Baase EG.
Physiology & behavior. 2020 May;219()112830.
Binge eating involves eating larger than normal quantities of food within a discrete period of time. The neurohormonal controls governing binge-like palatable food intake are not well understood. Glucagon-like peptide-1 (GLP-1), a hormone produced peripherally in the intestine and centrally in the n
PMID 32061682

Mapping of Sensory Nerve Subsets within the Vagal Ganglia and the Brainstem Using Reporter Mice for Pirt, TRPV1, 5-HT3, and Tac1 Expression.

Kim SH, Hadley SH, Maddison M, Patil M, Cha B, Kollarik M, Taylor-Clark TE.
eNeuro. ;7(2).
Vagal afferent sensory nerves, originating in jugular and nodose ganglia, are composed of functionally distinct subsets whose activation evokes distinct thoracic and abdominal reflex responses. We used Cre-expressing mouse strains to identify specific vagal afferent populations and map their central
PMID 32060036

Leptin receptor-expressing nucleus tractus solitarius neurons suppress food intake independently of GLP1 in mice.

Cheng W, Ndoka E, Hutch C, Roelofs K, MacKinnon A, Khoury B, Magrisso J, Kim KS, Rhodes CJ, Olson DP, Seeley RJ, Sandoval D, Myers MG.
JCI insight. 2020 Apr;5(7).
Leptin receptor-expressing (LepRb-expressing) neurons of the nucleus tractus solitarius (NTS; LepRbNTS neurons) receive gut signals that synergize with leptin action to suppress food intake. NTS neurons that express preproglucagon (Ppg) (and that produce the food intake-suppressing PPG cleavage prod
PMID 32182221

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