testicular atrophy

WordNet

1. a decrease in size of an organ caused by disease or disuse (同)wasting, wasting away
2. undergo atrophy; "Muscles that are not used will atrophy"
3. any weakening or degeneration (especially through lack of use) (同)withering
4. of or involving the testes; "testicular cancer"

PrepTutorEJDIC

1. (栄養不良などによる)萎縮(いしゅく) / (一般的に)衰退,退化 / 萎縮する,衰退する / …'を'萎縮させる,衰退させる

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/08/30 11:07:51」(JST)

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Testicular atrophy is a medical condition in which the male reproductive organs (the testes, which in humans are located in the scrotum) diminish in size and may be accompanied by loss of function. This does not refer to temporary changes, such as those brought on by cold.

Causes

Some supplements and medications can cause testicular atrophy. Anabolic-Androgenic Steroids (AAS) can cause testicular atrophy by reducing the amount of luteinizing hormone (LH) produced by the pituitary gland. Some weight loss fruit extracts such as Garcinia cambogia can also be highly toxic to the testis. LH stimulates the testicles to produce testosterone. Testicular atrophy is also a side-effect of steroid use. Testicular atrophy caused by steroid use can be prevented by taking hCG, a drug which mimics the effect of LH. However, hCG will simply address the symptoms. Endogenous levels of anabolic-androgenic steroids will remain the cause, and testicular atrophy will continue until the male body regains homeostasis. It is unclear how long hCG can be administered to a male on anabolic-androgenic steroids before desensitization occurs.

See also

• Orchitis

References

• High dose of Garcinia cambogia is effective in suppressing fat accumulation in developing male Zucker obese rats, but highly toxic to the testis

External links

• Following Inguinal Hernia repair

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 性腺機能低下を呈する男性の臨床的特徴および診断 clinical features and diagnosis of male hypogonadism
• 2. 高齢男性におけるテストステロン欠乏症の概要 overview of testosterone deficiency in older men
• 3. 性腺機能低下を呈する男性に対するテストステロン治療 testosterone treatment of male hypogonadism
• 4. 女性におけるアンドロゲン欠乏症および治療の概要 overview of androgen deficiency and therapy in women
• 5. Uncommon congenital adrenal hyperplasias

English Journal

• NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease.

• Pouladi MA, Brillaud E, Xie Y, Conforti P, Graham RK, Ehrnhoefer DE, Franciosi S, Zhang W, Poucheret P, Compte E, Maurel JC, Zuccato C, Cattaneo E, Néri C, Hayden MR.SourceCentre for Molecular Medicine and Therapeutics, University of British Columbia, and Child and Family Research Institute, Vancouver, BC, Canada; Translational Laboratory in Genetic Medicine (TLGM), Department of Medicine, National University of Singapore, and Agency for Science, Technology and Research (A*STAR), Singapore 117609, Singapore.
• Neurobiology of disease.Neurobiol Dis.2012 Dec;48(3):282-9. doi: 10.1016/j.nbd.2012.06.026. Epub 2012 Jul 10.
• Huntington disease (HD), a neurodegenerative disorder caused by an expanded CAG repeat in the HTT gene, remains without a treatment to modify the course of the illness. Lithium, a drug widely used for the treatment of bipolar disorder, has been shown to exert neuroprotective effects in a number of m
• PMID 22796360

• Testicular microlithiasis: is there a need for surveillance in the absence of other risk factors?

• Richenberg J, Brejt N.SourceDepartment of Radiology, Brighton and Sussex University Hospitals NHS Trust, Eastern Road, Brighton, BN2 5BE, UK, Jonathan.Richenberg@bsuh.nhs.uk.
• European radiology.Eur Radiol.2012 Nov;22(11):2540-6. doi: 10.1007/s00330-012-2520-4. Epub 2012 Jun 19.
• OBJECTIVE: Ultrasound surveillance of patients with testicular microlithiasis (TM) has been advocated following the reported association with testicular cancer. The aim of this study was to assess the evidence base supporting such surveillance.METHODS: Formal literature review identified cohort stud
• PMID 22710430

Japanese Journal

• Clinical and Pathological Features of Ascending Testis

• Yoshida Tatsuyuki,[大野 耕一],[諸富 善樹] [他]
• Osaka City Medical journal 55(2), 81-87, 2009-12
• NAID 110007453668

• The protective effect of dexpanthenol on testicular atrophy at 60th day following experimental testicular torsion

• ETENSEL Barlas,OZKISACIK Sezen,OZKARA Esra,SERBEST Yesim Aksu,OZTAN Onur,YAZICI Mesut,GURSOY Harun
• Pediatric surgery international 23(3), 271-275, 2007-03-01
• NAID 10027855793

Related Links

• Testicular atrophy - Wikipedia, the free encyclopedia

Testicular atrophy is a medical condition in which the male reproductive organs ( the testes, which in humans are located in the scrotum) diminish in size and may be accompanied by loss of function. This does not refer to temporary changes, ...

• What Is Testicular Atrophy?

Testicular atrophy is a condition in which a man's testicles shrink. There are a number of causes of testicular atrophy, including...

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★リンクテーブル★

リンク元	「精巣萎縮」「精巣萎縮症」
関連記事	「testicular」「atrophy」

「精巣萎縮」

　　[★]

英

testicular atrophy

関

精巣萎縮症

「精巣萎縮症」

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英

testicular atrophy

関

精巣萎縮

「testicular」

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• adj.

• 精巣の、睾丸の

関

testes、testicle、testis

　

「atrophy」

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• n.

• 萎縮