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English Journal

Comparison of the risk of surgical site infection and feasibility of surgery between sennoside versus polyethylene glycol as a mechanical bowel preparation of elective colon cancer surgery: a randomized controlled trial.

Tajima Y1, Ishida H2, Yamamoto A2, Chika N2, Onozawa H2, Matsuzawa T2, Kumamoto K2, Ishibashi K2, Mochiki E2.
Surgery today.Surg Today.2016 Jun;46(6):735-40. doi: 10.1007/s00595-015-1239-7. Epub 2015 Aug 30.
PURPOSE: To validate the usefulness of sennoside as a substitute for polyethylene glycol (PEG) as a mechanical bowel preparation (MBP) for elective colon cancer surgery.METHODS: We performed a prospective randomized non-inferiority trial comparing the use of sennoside and PEG in MBP for elective col
PMID 26319220

Effects of Glycosylation on Biodistribution and Imaging Quality of Necrotic Myocardium of Iodine-131-Labeled Sennidins.

Li L1,2,3, Zhang D2,3, Yang S2,3, Song S4, Li J1,2,3, Wang Q2,3, Wang C1,2,3, Feng Y2,3,5, Ni Y2,3,5, Zhang J6,7, Liu W8, Yin Z9.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.Mol Imaging Biol.2016 May 12. [Epub ahead of print]
PURPOSE: Sennidins are necrosis-avid agents for noninvasive assessment of myocardial viability which is important for patients with myocardial infarction (MI). However, high accumulation of radioactivity in the liver interferes with the assessment of myocardial viability. In this study, we compared
PMID 27172937

Arai M1, Nakada Y, Kajiwara K, Kimura M, Ishii N.
The Tokai journal of experimental and clinical medicine.Tokai J Exp Clin Med.2016 Mar 20;41(1):24-9.
OBJECTIVE: The aim of this study was to develop a method of removing sennoside to reduce the cathartic effect of rhubarb while conserving its other pharmacological activities.METHODS: Rhubarb powder was steam autoclaved at 121°C and 0.14 MPa for 20, 60, or 120 minutes, and HPLC analysis was conduct
PMID 27050892