English Journal

Extramedullary plasmacytoma of the thyroid, associated with follicular colonization and stromal deposition of polytypic immunoglobulins and major histocompatibility antigens. Possible categorization in MALT lymphoma.

Aihara H1, Tsutsumi Y, Ishikawa H.
Acta pathologica japonica.Acta Pathol Jpn.1992 Sep;42(9):672-83.
A 78-year-old woman complaining of a neck mass underwent right hemithyroidectomy. The 7 x 6 cm thyroid tumor consisted predominantly of mildly atypical, epithelial membrane antigen-positive plasma cells and scattered lymphoid follicles. Features of follicular colonization (plasma cell infiltration i
PMID 1476063

Isaacson P.
Journal of clinical pathology.J Clin Pathol.1979 Aug;32(8):802-7.
Many B-cell lymphomas can be shown to contain cytoplasmic immunoglobulin which is characteristically monotypic with respect to light chains. In Hodgkin's disease, however, the Reed-Sternberg cells have been shown to contain both immunoglobulin light chains. This finding, which is also present in som
PMID 117027

Isaacson P, Wright DH.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.J Histochem Cytochem.1979 Aug;27(8):1197-9.
A number of immunoperoxidase studies of malignant lymphomas have reported polytypic light chain staining of neoplastic cells, thus bringing into question the concept that the monoclonality of B cell lymphomas is reflected in their synthesis of monotypic light chain. In this study of a large number o
PMID 90079