WordNet

the property of something that can be pervaded by a liquid (as by osmosis or diffusion) (同)permeableness

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Exposure to endosulfan increases endothelial permeability by transcellular and paracellular pathways in relation to cardiovascular diseases.

Xu D1, Liu T2, Lin L3, Li S4, Hang X5, Sun Y6.
Environmental pollution (Barking, Essex : 1987).Environ Pollut.2017 Apr;223:111-119. doi: 10.1016/j.envpol.2016.12.051. Epub 2017 Jan 17.
Exposure to environmental pollutants results in out-of-balance of vascular homeostasis. Endothelial dysfunction leads to a disruption of the endothelial permeability characteristics, associated with cardiovascular diseases. We previously reported that endosulfan could cause endothelial dysfunction,
PMID 28108160

Arsenic downregulates tight junction claudin proteins through p38 and NF-κB in intestinal epithelial cell line, HT-29.

Jeong CH1, Seok JS1, Petriello MC2, Han SG3.
Toxicology.Toxicology.2017 Mar 15;379:31-39. doi: 10.1016/j.tox.2017.01.011. Epub 2017 Jan 20.
Arsenic is a naturally occurring metalloid that often is found in foods and drinking water. Human exposure to arsenic is associated with the development of gastrointestinal problems such as fluid loss, diarrhea and gastritis. Arsenic is also known to induce toxic responses including oxidative stress
PMID 28115242

Cellular internalization, transcellular transport, and cellular effects of silver nanoparticles in polarized Caco-2 cells following apical or basolateral exposure.

Imai S1, Morishita Y1, Hata T2, Kondoh M2, Yagi K2, Gao JQ3, Nagano K1, Higashisaka K1, Yoshioka Y4, Tsutsumi Y5.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2017 Mar 11;484(3):543-549. doi: 10.1016/j.bbrc.2017.01.114. Epub 2017 Jan 24.
When considering the safety of ingested nanomaterials, it is important to quantitate their transfer across intestinal cells; however, little information exists about the effects of nanomaterial size or exposure side (apical versus basolateral epithelial surface) on nanomaterial transfer. Here, we ex
PMID 28130106

Enhanced Oral Bioavailability of Morin Administered in Mixed Micelle Formulation with PluronicF127 and Tween80 in Rats

, , [他], , , , , ,
Biological and Pharmaceutical Bulletin 38(2), 208-217, 2015
… In Caco-2 cells, absorption permeability of morin from the novel formulation was increased 3.6-fold compared with that of morin alone. … P-gp inhibition by cyclosporine A (CsA) increased absorptive permeability of morin 2.4-fold but decreased the efflux of morin by 52%, which was consistent with increased plasma concentration of morin in the pretreatment of CsA in rats. … Moreover, morin formulation increased paracellular permeability of Lucifer yellow by 1.6–1.8 fold. …
NAID 130004872251

Permeability of Exendin-4-Loaded Chitosan Nanoparticles across MDCK Cell Monolayers and Rat Small Intestine

古瀬幹夫
薬学雑誌. 乙号 134(5), 615-621, 2014
… Within an epithelial cellular sheet, the paracellular pathway can be divided into two routes: one between two adjacent cells and one at tricellular contacts, where the vertices of three cells meet. … For epithelial barrier function, tight junctions restrict solute permeability through the paracellular pathway between two cells, while tricellular contacts contain specialized structures of tight junctions, named tricellular tight junctions (tTJs). …
NAID 130004756433