癌遺伝子産物gp140
WordNet
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- a gene that disposes normal cells to change into cancerous tumor cells (同)transforming_gene
PrepTutorEJDIC
- 蛋白(たんばく)質
UpToDate Contents
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English Journal
- Mutation in the first Ig-like domain of Kit leads to JAK2 activation and myeloproliferation in mice.
- Huang Z1, Ruan HB1, Zhang ZD2, Chen W3, Lin Z1, Zeng H1, Gao X4.
- The American journal of pathology.Am J Pathol.2014 Jan;184(1):122-32. doi: 10.1016/j.ajpath.2013.09.019. Epub 2013 Nov 7.
- Myeloproliferative neoplasms constitute a group of hematopoietic neoplasms at the myeloid stem cell level. Although mutations in the receptor tyrosine kinase KIT have been identified in patients with myeloproliferative neoplasm, the functional causality is unknown because of a lack of animal models.
- PMID 24211109
- Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor.
- Zhang C1, Ibrahim PN, Zhang J, Burton EA, Habets G, Zhang Y, Powell B, West BL, Matusow B, Tsang G, Shellooe R, Carias H, Nguyen H, Marimuthu A, Zhang KY, Oh A, Bremer R, Hurt CR, Artis DR, Wu G, Nespi M, Spevak W, Lin P, Nolop K, Hirth P, Tesch GH, Bollag G.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2013 Apr 2;110(14):5689-94. doi: 10.1073/pnas.1219457110. Epub 2013 Mar 14.
- Inflammation and cancer, two therapeutic areas historically addressed by separate drug discovery efforts, are now coupled in treatment approaches by a growing understanding of the dynamic molecular dialogues between immune and cancer cells. Agents that target specific compartments of the immune syst
- PMID 23493555
- Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human B lymphoma cell surface triggers Cbl tyrosine phosphorylation, its association with p85 subunit, Crk-L and Syk and its dissociation with Vav.
- Lottin-Divoux S1, Jean D, Le Romancer M, Frade R.
- Cellular signalling.Cell Signal.2006 Aug;18(8):1219-25. Epub 2005 Nov 14.
- It is well established that CD21 activation on human B cell surface triggers B cell proliferation. We previously demonstrated that CD21 activation also triggers tyrosine phosphorylation of two components, p95 and p120, both interacting with SH2 domains of the p85 subunit of PI 3-kinase. We successiv
- PMID 16289966
Related Links
- oncogene protein gp140(v-fms) definition from the mondofacto online medical dictionary help contact sitemap oncogene protein gp140(v-fms) definition home dictionary word tools courses study skills forum about us Search fms ...
- Oncogene Protein gp140(v-fms): Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sar) ... Illness finder is a diagnostic medicine tool for educational purpose that looks up your patients ...
Related Pictures
★リンクテーブル★
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- 英
- oncogene protein gp140
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- 関
- oncogene product、oncoprotein