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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/04/27 09:13:43」(JST)
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Mephenoxalone
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| Systematic (IUPAC) name |
| 5-[(2-methoxyphenoxy)methyl]-1,3-oxazolidin-2-one |
| Clinical data |
| AHFS/Drugs.com |
International Drug Names |
| Pregnancy cat. |
? |
| Legal status |
? |
| Identifiers |
| CAS number |
70-07-5 |
| ATC code |
N05BX01 |
| PubChem |
CID 6257 |
| UNII |
CZ87T54W8W Y |
| KEGG |
D07318 Y |
| Chemical data |
| Formula |
C11H13NO4 |
| Mol. mass |
223.225 g/mol |
Y (what is this?) (verify)
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Mephenoxalone (Dorsiflex, Moderamin Control-OM) is a muscle relaxant and mild anxiolytic. It inhibits neuron transmission, that will produce skeletal muscle relaxation by inhibits the reflex arc of skeletal muscle. As the effect of muscle relaxation, mephenoxalone affects mental condition and also a treatment for nervousness and anxiety.
References
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This article does not cite any references or sources. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. (March 2010) |
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Anxiolytics (N05B)
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GABAA
PAMs |
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non-N05B
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- Alcohols (2M2B, Ethanol (beverage)
- Ethchlorvynol
- Methylpentynol
- Chlormezanone
- Inhalants
- Etifoxine
- Kavalactones (Kava)
- Skullcap
- Valerenic acid (Valerian)
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1,4 Benzodiazepines
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- Bromazepam
- Camazepam
- Chlordiazepoxide
- Clobazam
- Clorazepate
- Clotiazepam
- Cloxazolam
- Diazepam#
- Ethyl Loflazepate
- Fludiazepam
- Flurazepam
- Halazepam
- Ketazolam
- Lorazepam
- Medazepam
- Nordazepam
- Oxazepam
- Pinazepam
- Prazepam
- Temazepam
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Triazolobenzodiazepines
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Imidazobenzodiazepines
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Thienotriazolodiazepines
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Carbamates
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- Carisoprodol
- Emylcamate
- Mebutamate
- Meprobamate
- Methocarbamol
- Phenprobamate
- Procymate
- Tybamate
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Nonbenzodiazepines
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- Abecarnil§
- Adipiplon
- Alpidem‡
- CGS-8216
- CGS-9896
- CGS-13767
- CGS-20625
- ELB-139
- Fasiplon
- GBLD-345
- Gedocarnil
- L-838,417
- NS-2664
- NS-2710
- Pagoclone§
- Panadiplon
- Pipequaline
- RWJ-51204
- SB-205,384
- SL-651,498
- Taniplon
- TP-003
- TP-13
- TPA-023
- Y-23684
- ZK-93423
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Pyrazolopyrimidines
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- Cartazolate
- Divaplon
- Etazolate
- ICI-190,622
- Ocinaplon
- Tracazolate
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| α2δ VDCC Blockers |
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| 5-HT1A Agonists, Azapirones |
- Buspirone
- Gepirone
- Tandospirone; Others: Flesinoxan
- Naluzotan
- Oxaflozane
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| H1 Antagonists |
- Diphenylmethanes: Captodiame
- Hydroxyzine; Others: Brompheniramine
- Chlorpheniramine
- Pheniramine
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| CRH1 Antagonists |
- Antalarmin
- CP-154,526
- Pexacerfont
- Pivagabine
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| NK2 Antagonists |
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| MCH1 antagonists |
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| mGluR2/3 Agonists |
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| mGluR5 NAMs |
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| TSPO agonists |
- DAA-1097
- DAA-1106
- Emapunil
- FGIN-127
- FGIN-143
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| σ1 agonists |
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| Others |
- Benzoctamine
- Carbetocin
- Demoxytocin
- GHB
- Mephenoxalone
- Mepiprazole
- Oxanamide
- Oxytocin
- Picamilon
- Phenibut§
- Promoxolane
- Tofisopam
- Trimetozine
- WAY-267,464
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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dsrd (o, p, m, p, a, d, s), sysi/epon, spvo
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proc (eval/thrp), drug (N5A/5B/5C/6A/6B/6D)
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Skeletal muscle relaxants (M03)
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Peripherally acting
(primarily antinicotinic,
NMJ block) |
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Non-depolarizing
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Curare alkaloids
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- Alcuronium
- Dimethyltubocurarine
- Tubocurarine
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4° ammonium agents
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- ultra-short duration: Gantacurium
- short duration: Mivacurium
- Chandonium
- intermediate duration: Atracurium
- Cisatracurium
- Fazadinium
- Rocuronium
- Vecuronium
- long duration: Doxacurium
- Dimethyltubocurarine
- Pancuronium
- Pipecuronium
- Laudexium
- Gallamine
- unsorted: Hexafluronium (Hexafluorenium)
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Depolarizing
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- Choline derivatives: Suxamethonium (Succinylcholine)
- Polyalkylene derivatives: Hexamethonium
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ACh release inhibitors
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| Centrally acting |
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Carbamic acid esters
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- Carisoprodol
- Cyclarbamate
- Difebarbamate
- Febarbamate
- Meprobamate
- Methocarbamol
- Phenprobamate
- Styramate
- Tybamate
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Benzodiazepines
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- Bentazepam
- Diazepam
- Clonazepam
- Flunitrazepam
- Lorazepam
- Nitrazepam
- Tetrazepam
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Nonbenzodiazepines
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Thienodiazepines
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Quinazolines
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Anticholinergics (Antimuscarinics)
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- Cyclobenzaprine
- Orphenadrine
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Other
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- Baclofen
- Chlormezanone
- Chlorphenesin
- Chlorzoxazone
- Donepezil
- Eperisone
- Fenyramidol
- Flopropione
- GHB
- Mephenesin
- Mephenoxalone
- Metaxalone
- Phenibut
- Pridinol
- Promoxolane
- Quinine
- Thiocolchicoside
- Tizanidine
- Tolperisone
- Trazodone
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| Directly acting |
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anat (h/n, u, t/d, a/p, l)/phys/devp/hist
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noco (m, s, c)/cong (d)/tumr, sysi/epon, injr
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English Journal
- Effect of acupressure and trigger points in treating headache: a randomized controlled trial.
- Hsieh LL, Liou HH, Lee LH, Chen TH, Yen AM.SourceDepartment of Rehabilitation, Kaohsiung Medical University, Taiwan. chenlin@ntu.edu.tw
- The American journal of Chinese medicine.Am J Chin Med.2010;38(1):1-14.
- The efficacy of acupressure in relieving pain has been documented; however, its effectiveness for chronic headache compared to the muscle relaxant medication has not yet been elucidated. To address this, a randomized, controlled clinical trial was conducted in a medical center in Southern Taiwan in
- PMID 20128040
- Percutaneous Achilles tendon repair combined with real-time sonography.
- Blankstein A, Israeli A, Dudkiewicz I, Chechik A, Ganel A.SourceDepartment of Orthopedic Surgery, Sheba Medical Center, Tel Hashomer, Israel. blankali@zahav.net.il
- The Israel Medical Association journal : IMAJ.Isr Med Assoc J.2007 Feb;9(2):83-5.
- BACKGROUND: When encountering complaints of pain in the area of Achilles tendon with a suspected lesion, the clinician seldom reaches a precise diagnosis based only on X-ray and clinical examination. Ultrasonography is useful for evaluating the pathology and treatment.OBJECTIVES: To assess the relat
- PMID 17348477
Japanese Journal
- Determination of mephenoxalone in human plasma sample by high-performance liquid chromatography-fluorescence detection
- UANG Yow-Shieng,CHEN I.-Kei,WANG Li-Hsuan,HSU Kuang-Yang
- Journal of chromatography. B, Biomedical sciences and applications 759(1), 91-97, 2001-08-05
- NAID 10012255409
Related Links
- Mephenoxalone (Dorsiflex, Moderamin Control-OM) is a muscle relaxant and mild anxiolytic. It inhibits neuron transmission, that will produce skeletal muscle relaxation by inhibits the reflex arc of skeletal muscle. As the effect of ...
- Mephenoxalone is a medicine available in a number of countries worldwide. A list of US medications equivalent to Mephenoxalone is available on the Drugs.com website. ... Drugs.com provides accurate and independent information ...
- Mephenoxalone U.C. Pharma is a medicine available in a number of countries worldwide. A list of US medications equivalent to Mephenoxalone U.C. Pharma is available on the Drugs.com website.
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