leukotoxin

English Journal

Song H1, Wu H2, Geng Z3, Sun C2, Ren S1, Wang D2, Zhang M2, Liu F2, Xu W4.
Food chemistry.Food Chem.2016 Nov 1;210:338-43. doi: 10.1016/j.foodchem.2016.04.086. Epub 2016 Apr 19.
9,10-Epoxyoctadec-12-enoic acid (Ltx) and 9,10-dihydroxy-12-octadecenoic acid (Ltxd), oxidation products of Linoleic acid, are of biological significance. In this paper, a method was developed for simultaneous determination of Ltx and Ltxd in cured meat products. The analytes were separated by high
PMID 27211656

In vitro complement activation, adherence to red blood cells and induction of mononuclear cell cytokine production by four strains of Aggregatibacter actinomycetemcomitans with different fimbriation and expression of leukotoxin.

Damgaard C1,2, Reinholdt J3, Palarasah Y4, Enevold C5,6, Nielsen C7, Brimnes MK6, Holmstrup P5, Nielsen CH5,6.
Journal of periodontal research.J Periodontal Res.2016 Sep 24. doi: 10.1111/jre.12414. [Epub ahead of print]
BACKGROUND AND OBJECTIVE: The periodontal pathogen Aggregatibacter actinomycetemcomitans has been proposed as pro-atherogenic, and complement-mediated adherence to red blood cells (RBCs) may facilitate its systemic spread. We investigated the ability of four strains of A. actinomycetemcomitans with
PMID 27663487

Identification of Leukotoxin and other vaccine candidate proteins in a Mannheimia haemolytica commercial antigen.

Tucci P1, Estevez V2, Becco L2, Cabrera-Cabrera F3, Grotiuz G4, Reolon E4, Marín M3.
Heliyon.Heliyon.2016 Sep 19;2(9):e00158. eCollection 2016.
Bovine Respiratory Disease is the most costly disease that affects beef and dairy cattle industry. Its etiology is multifactorial, arising from predisposing environmental stress conditions as well as the action of several different respiratory pathogens. This situation has hindered the development o
PMID 27699279

Anticytotoxic Effect of Green Tea Catechin on Aggregatibacter actinomycetemcomitans Vesicles

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International Journal of Oral-Medical Sciences 11(2), 101-105, 2012
… One of the potential virulence factors produced by Aggregatibacter actinomycetemcomitans is a leukotoxin, which is secreted to membranous vesicles and to the culture supernatant, generating membrane pores and killing several lymphoid cell types. …
NAID 130002571559

Neutrophil-derived resistin release induced by Aggregatibacter actinomycetemcomitans.

Furugen Reiko,Hayashida Hideaki,Yoshii Yumiko,Saito Toshiyuki
FEMS Microbiology Letters 321(2), 175-182, 2011-08
… In contrast, the level of resistin was remarkably low when neutrophils were exposed to two other strains that produce minimal levels of leukotoxin and a further isogenic mutant strain incapable of producing leukotoxin. … actinomycetemcomitans-expressed leukotoxin induces extracellular release of human neutrophil-derived resistin by interacting with LFA-1 on the surface of neutrophils and, consequently, activating Src family tyrosine kinases. …
NAID 120003751834

Effects of Catechin Gallate on Bactericidal Action and Leukotoxic Activity of Aggregatibacter actinomycetemcomitans

International Journal of Oral-Medical Sciences 10(1), 20-24, 2011
… This study is to investigate the effects of green tea catechins on bacterial growth and leukotoxin activity of A. … The green tea catechin with galloyl residue (Cg, GCg, ECG, and EGCg) was to inactivate leukotoxin from A. …
NAID 130000769912