WordNet

first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
the 1st letter of the Greek alphabet
the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
early testing stage of a software or hardware product; "alpha version"
a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system
any high mountain

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1. 複合免疫不全 combined immunodeficiencies
2. リウマチ性疾患におけるサイトカインネットワーク：治療の意味 cytokine networks in rheumatic diseases implications for therapy
3. 喘息治療の代替剤および経験的薬剤 alternative and experimental agents for the treatment of asthma
4. 思春期および成人における重症喘息の治療 treatment of severe asthma in adolescents and adults
5. 肥満細胞由来のメディエーター mast cell derived mediators

Angiogenesis related genes NOS3, CD14, MMP3 and IL4R are associated to VEGF gene expression and circulating levels in healthy adults.

Saleh A1, Stathopoulou MG2, Dadé S3, Ndiaye NC4, Azimi-Nezhad M5,6, Murray H7, Masson C8, Lamont J9, Fitzgerald P10, Visvikis-Siest S11,12.
BMC medical genetics.BMC Med Genet.2015 Oct 5;16:90. doi: 10.1186/s12881-015-0234-6.
BACKGROUND: Vascular endothelial growth factor (VEGF) plays a key role in angiogenesis. The aim was to assess the genetic connections between the angiogenesis-related NOS3, CD14, MMP3, IL4R, IL4 genes and VEGF expression and plasma levels.METHODS: The associations between VEGF plasma levels with the
PMID 26437765

Disruption of TIM-4 in dendritic cell ameliorates hepatic warm IR injury through the induction of regulatory T cells.

Li J1, Zhao X2, Liu X2, Liu H3.
Molecular immunology.Mol Immunol.2015 Aug;66(2):117-25. doi: 10.1016/j.molimm.2015.02.004. Epub 2015 Mar 12.
Hepatic ischaemia reperfusion (IR) injury results from the infiltration of multiple immune cells especially dendritic cells (DC). T-cell immunoglobulin-domain and mucin-domain 4 (TIM-4) is a type I cell-surface glycoprotein which is extensively expressed on antigen presenting cells (APC) like DC and
PMID 25771178

CD300f associates with IL-4 receptor α and amplifies IL-4-induced immune cell responses.

Moshkovits I1, Karo-Atar D1, Itan M1, Reichman H1, Rozenberg P1, Morgenstern-Ben-Baruch N1, Shik D1, Ejarque-Ortiz A2, Hershko AY3, Tian L4, Coligan JE4, Sayós J2, Munitz A5.
Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2015 Jul 14;112(28):8708-13. doi: 10.1073/pnas.1507625112. Epub 2015 Jun 29.
IL-4 receptor (R) α, the common receptor chain for IL-4 and IL-13, is a critical component in IL-4- and IL-13-mediated signaling and subsequent effector functions such as those observed in type 2 inflammatory responses. Nonetheless, the existence of intrinsic pathways capable of amplifying IL-4Rα-
PMID 26124135