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- 1. 成人におけるステロイド抵抗性およびステロイド依存性の潰瘍性大腸炎に対するアプローチ approach to adults with steroid refractory and steroid dependent ulcerative colitis
- 2. 成人における重症または難治性クローン病の内科的マネージメントの概要 overview of the medical management of severe or refractory crohn disease in adults
- 3. 炎症の病因における白血球内皮細胞接着 leukocyte endothelial adhesion in the pathogenesis of inflammation
- 4. 白血球粘着不全症 leukocyte adhesion deficiency
- 5. 成人における再発寛解型多発性硬化症に対するナタリズマブ natalizumab for relapsing remitting multiple sclerosis in adults
English Journal
- Geometric guidance of integrin mediated traction stress during stem cell differentiation.
- Lee J1, Abdeen AA1, Tang X2, Saif TA2, Kilian KA3.
- Biomaterials.Biomaterials.2015 Nov;69:174-83. doi: 10.1016/j.biomaterials.2015.08.005. Epub 2015 Aug 5.
- Cells sense and transduce the chemical and mechanical properties of their microenvironment through cell surface integrin receptors. Traction stress exerted by cells on the extracellular matrix mediates focal adhesion stabilization and regulation of the cytoskeleton for directing biological activity.
- PMID 26285084
- Biodistribution of the (18)F-FPPRGD2 PET radiopharmaceutical in cancer patients: an atlas of SUV measurements.
- Minamimoto R1,2, Jamali M3,4, Barkhodari A3, Mosci C3, Mittra E3, Shen B4, Chin F4, Gambhir SS3,4, Iagaru A5.
- European journal of nuclear medicine and molecular imaging.Eur J Nucl Med Mol Imaging.2015 Nov;42(12):1850-8. doi: 10.1007/s00259-015-3096-4. Epub 2015 Jun 11.
- PURPOSE: The aim of this study was to investigate the biodistribution of 2-fluoropropionyl-labeled PEGylated dimeric arginine-glycine-aspartic acid (RGD) peptide (PEG3-E[c{RGDyk}]2) ((18)F-FPPRGD2) in cancer patients and to compare its uptake in malignant lesions with (18)F-FDG uptake.METHODS: A tot
- PMID 26062933
- Evaluation of two novel (64)Cu-labeled RGD peptide radiotracers for enhanced PET imaging of tumor integrin αvβ3.
- Hernandez R1, Czerwinski A2, Chakravarty R3, Graves SA1, Yang Y3, England CG3, Nickles RJ1, Valenzuela F2, Cai W4,5,6.
- European journal of nuclear medicine and molecular imaging.Eur J Nucl Med Mol Imaging.2015 Nov;42(12):1859-68. doi: 10.1007/s00259-015-3085-7. Epub 2015 May 28.
- PURPOSE: Our goal was to demonstrate that suitably derivatized monomeric RGD peptide-based PET tracers, targeting integrin αvβ3, may offer advantages in image contrast, time for imaging, and low uptake in nontarget tissues.METHODS: Two cyclic RGDfK derivatives, (PEG)2-c(RGDfK) and PEG4-SAA4-c(RGDf
- PMID 26016906
Japanese Journal
- HOXD3-overexpression increases integrin alphavbeta3 expression and deprives E-cadherin while it enhances cell motility in A549 cells.
- Clinical & Experimental Metastasis 23(7-8), 381-390, 2006-12
- NAID 120000972889
- Simultaneous integrin alphavbeta3 and glycoprotein IIb/IIIa inhibition causes reduction in infarct size in a model of acute coronary thrombosis and primary angioplasty
- Cardiovasc Res 66, 552-561, 2005
- NAID 30006833145
- alphavbeta3 integrin-dependent endothelial cell dynamics in vivo
- Development 131, 2887-2897, 2004
- NAID 30002333505
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- Hans und Blanca Moser Stiftung Dr.med.univ. Alexandra Martel 4 2. Abstract Integrins are a major family of cell-surface-adhesion receptors that are expressed in all metazoans. The integrin receptor alphavbeta3 has been ...
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| リンク元 | 「vitronectin receptor」 |
| 関連記事 | 「integrin」 |