WordNet

utter `hem or `ahem
the edge of a piece of cloth; especially the finished edge that has been doubled under and stitched down; "the hem of her dress was stained"; "let down the hem"; "he stitched weights into the curtains hem"; "it seeped along the hem of his jacket"
the utterance of a sound similar to clearing the throat; intended to get attention, express hesitancy, fill a pause, hide embarrassment, warn a friend, etc. (同)ahem
fold over and sew together to provide with a hem; "hem my skirt"
block the action of
put down by force or intimidation; "The government quashes any attempt of an uprising"; "China keeps down her dissidents very efficiently"; "The rich landowners subjugated the peasants working the land" (同)quash, keep_down, subdue, subjugate, reduce
a reddish-brown chloride of heme; produced from hemoglobin in laboratory tests for the presence of blood (同)protohemin
restrained or managed or kept within certain bounds; "controlled emotions"; "the controlled release of water from reservoirs"
an agent that represses (同)represser

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Integration of PKR-dependent translation inhibition with innate immunity is required for a coordinated anti-viral response.

Dalet A1, Gatti E2, Pierre P3.
FEBS letters.FEBS Lett.2015 Jun 22;589(14):1539-45. doi: 10.1016/j.febslet.2015.05.006. Epub 2015 May 12.
Viral triggering of the innate immune response in infected cells aims at delaying viral replication and prevents tissue spreading. Viral replication is delayed by host protein synthesis inhibition and infected cell apoptosis on one hand, while infection spreading is controlled by the synthesis of sp
PMID 25979169

Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling.

Carrara M1, Prischi F1, Nowak PR1, Ali MM2.
The EMBO journal.EMBO J.2015 Jun 3;34(11):1589-600. doi: 10.15252/embj.201489183. Epub 2015 Apr 28.
Stress caused by accumulation of misfolded proteins within the endoplasmic reticulum (ER) elicits a cellular unfolded protein response (UPR) aimed at maintaining protein-folding capacity. PERK, a key upstream component, recognizes ER stress via its luminal sensor/transducer domain, but the molecular
PMID 25925385

Clinical characteristics and molecular genetic analysis of 22 patients with neonatal diabetes from the South-Eastern region of Turkey: predominance of non-KATP channel mutations.

Demirbilek H1, Arya VB2, Ozbek MN3, Houghton JA3, Baran RT3, Akar M3, Tekes S3, Tuzun H3, Mackay DJ3, Flanagan SE3, Hattersley AT3, Ellard S3, Hussain K4.
European journal of endocrinology / European Federation of Endocrine Societies.Eur J Endocrinol.2015 Jun;172(6):697-705. doi: 10.1530/EJE-14-0852. Epub 2015 Mar 9.
BACKGROUND: Neonatal diabetes mellitus (NDM) is a rare form of monogenic diabetes and usually presents in the first 6 months of life. We aimed to describe the clinical characteristics and molecular genetics of a large Turkish cohort of NDM patients from a single centre and estimate an annual inciden
PMID 25755231