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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2020/01/01 08:56:43」(JST)

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1. 同種造血細胞移植の適応判定determining eligibility for allogeneic hematopoietic cell transplantation [show details]
… allogeneic HCT must be compared with those of other treatment approaches. The role of allogeneic HCT in specific diseases is discussed in more detail separately. In general, allogeneic HCT may be considered …
2. 成人における造血細胞移植後の転帰および晩期合併症outcomes and late complications after hematopoietic cell transplantation in adults [show details]
…most later deaths. Unlike allogeneic HCT, patients who undergo autologous HCT do not experience graft-versus-host disease. Examples of outcomes after autologous HCT include: The estimated 20-year OS was …
3. 造血細胞移植後の悪性腫瘍malignancy after hematopoietic cell transplantation [show details]
… 20 years after allogeneic HCT and at 4 percent 10 years following autologous HCT. Solid tumors of practically every type have been described in the allogeneic and autologous HCT setting. Radiation exposure …
4. 造血細胞移植成人サバイバーの長期ケアlong term care of the adult hematopoietic cell transplantation survivor [show details]
…transplantation (HCT) has the potential to cure malignant (eg, leukemias, lymphomas) and nonmalignant disorders (eg, hemoglobinopathies). However, cure of the underlying disease by HCT is not necessarily …
5. 造血細胞移植後早期の合併症early complications of hematopoietic cell transplantation [show details]
…after autologous or allogeneic HCT. Longer-term complications of HCT are discussed separately. Factors that affect the nature and severity of complications after HCT vary with the individual patient …

English Journal

RKI-1447 suppresses colorectal carcinoma cell growth via disrupting cellular bioenergetics and mitochondrial dynamics.

Li L, Chen Q, Yu Y, Chen H, Lu M, Huang Y, Li P, Chang H.
Journal of cellular physiology. 2020 Jan;235(1)254-266.
Accumulated evidence suggested the importance of the Rho/Rho-kinase (ROCK) signaling pathway in cancer proliferation and invasion. However, its role in colorectal carcinoma (CRC) is not well understood. This study evaluated the effect of ROCK signaling pathway on CRC behavior on the basis of a novel
PMID 31237697

Clinical and economic burden of pre-emptive therapy of cytomegalovirus infection in hospitalized allogeneic hematopoietic cell transplant recipients.

El Haddad L, Ghantoji SS, Park AK, Batista MV, Schelfhout J, Hachem J, Lobo Y, Jiang Y, Rondon G, Champlin R, Chemaly RF.
Journal of medical virology. 2020 Jan;92(1)86-95.
Cytomegalovirus (CMV) infection remains a major complication after allogeneic hematopoietic cell transplantation (allo-HCT). We conducted a retrospective study to determine the clinical and economic burden of pre-emptive therapy (PET) for CMV infection in 100 consecutive hospitalized adult CMV posit
PMID 31448830

High-Content Screening for Cryptosporidium Drug Discovery.

Love MS, McNamara CW.
Methods in molecular biology (Clifton, N.J.). 2020 ;2052()303-317.
High-content screening (HCS) is a cell-based type of phenotypic screening that combines multiple simultaneous readouts with a high level of throughput. A particular benefit of this form of screening for drug discovery is the ability to perform the interrogation in a biologically relevant system. Thi
PMID 31452169

Japanese Journal

患者と医療者に｢優しい｣環境をめざした無菌室の新設

高橋彩,後藤清香,加藤元博,安部美樹子,中村有希,釼持瞳,森田秀一,松本有子,松本公一
日本造血細胞移植学会雑誌 9(1), 46-49, 2020
… <p> Hematopoietic stem cell transplantation (HCT) recipients should be accommodated for at least 2-3 weeks in a protective environment with high-efficiency particulate air (HEPA) filters. …
NAID 130007785188

移植を経験した子どもたち

井上雅美
日本造血細胞移植学会雑誌 9(1), 1-5, 2020
<p> 小児期に造血細胞移植を受けた長期生存者における様々な移植関連晩期合併症が報告されている。これらの晩期合併症は全身放射線照射（total body irradiation，TBI）や大量化学療法で構成される移植前処置によるものと慢性移植片対宿主病（graft-versus-host disease，GVHD）の影響によるものに大別される。特に乳幼児期に移植を受けた場合，TBIを用 …
NAID 130007785186

Initial human T-cell leukemia virus type 1 infection of the salivary gland epithelial cells requires a biofilm-like structure

Nakamura Hideki,Shimizu Toshimasa,Takatani Ayuko,Suematsu Takashi,Nakamura Tatsufumi,Kawakami Atsushi
Virus Research (269), 197643, 2019-06-21
… SGECs of patients with Sjögren's syndrome (SS) and non-SS subjects were co-cultured with the HTLV-1-infected cell line HCT-5 or MOLT-4, then immunofluorescence (IF), scanning and transmission electron microscopy (SEM/TEM) were employed. … The extracellular matrix and linker proteins galectin-3, agrin, and tetherin were expressed on the surfaces of both HCT-5 and MOLT-4 cells. … HTLV-1 Gag-positive spots were observed on adjacent SGECs after 1 h of co-culture with HCT-5. …
NAID 120006707263