WordNet

a substance from which another substance is formed (especially by a metabolic reaction)
a person who goes before or announces the coming of another (同)forerunner
a hormone secreted by the pancreas; stimulates increases in blood sugar levels in the blood (thus opposing the action of insulin)

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Nesfatin-1 stimulates glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide secretion from STC-1 cells in vitro.

Ramesh N1, Mortazavi S1, Unniappan S2.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2015 Jun 26;462(2):124-30. doi: 10.1016/j.bbrc.2015.04.100. Epub 2015 Apr 28.
Nesfatin-1 is an 82 amino acid peptide encoded in a secreted precursor, nucleobindin 2. It is an anorexigenic and insulinotropic peptide found abundantly in the hypothalamus, pancreas and gastric oxyntic mucosa. NUCB2 mRNA expression is 10 fold higher in the gastric mucosa than in brain, suggesting
PMID 25930999

Colocalization of insulin and glucagon in insulinoma cells and developing pancreatic endocrine cells.

Wang Z1, You J1, Xu S1, Hua Z2, Zhang W1, Deng T1, Fang N3, Fang Q1, Liu H1, Peng L1, Wang P4, Lou J5.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2015 Jun 12;461(4):598-604. doi: 10.1016/j.bbrc.2015.04.072. Epub 2015 Apr 23.
A significant portion of human and rat insulinomas coexpress multiple hormones. This character termed as multihormonality is also observed in some early pancreatic endocrine cells which coexpress insulin and glucagon, suggesting an incomplete differentiation status of both cells. Here we demonstrate
PMID 25912877

Xu G1, Li Z, Ding L, Tang H, Guo S, Liang H, Wang H, Zhang W.
Diabetologia.Diabetologia.2015 Jun 3. [Epub ahead of print]
AIMS/HYPOTHESIS: Glucagon-like peptide (GLP-1), an intestinal incretin produced in L cells through proglucagon processing, is released in response to meal intake. The intracellular mechanism by which L cells sense the organism energy level to coordinate the production of GLP-1 remains unclear. Mecha
PMID 26037201

Glucagon-like Peptide-2 Functions as an Anorexigenic Peptide not only in the Central Nervous System but also in the Peripheral Circulation in Broiler Chicks

Glucagon-like Peptide-2 Functions as an Anorexigenic Peptide not only in the Central Nervous System but also in the Peripheral Circulation in Broiler Chicks