English Journal

Dermoscopy of verrucous epidermal nevus: large brown circles as a novel feature for diagnosis.

Carbotti M1, Coppola R1, Graziano A1, Verona Rinati M1, Paolilli FL1, Zanframundo S1, Panasiti V1.
International journal of dermatology.Int J Dermatol.2016 Jun;55(6):653-6. doi: 10.1111/ijd.12948. Epub 2015 Oct 16.
BACKGROUND: The epidermal nevus is a hamartomatous proliferation of the epithelium that can involve keratinocytes, sebaceous glands, the pilosebaceous unit, and eccrine or apocrine glands. It occurs in one in 1000 live births and most commonly presents as the verrucous type. Dermoscopy is a non-inva
PMID 26475079

Immunohistochemical localization of irisin in skin, eye, and thyroid and pineal glands of the crested porcupine (Hystrix cristata).

Gençer Tarakçı B1, Girgin A1, Timurkaan S1, Yalçın MH1, Gür FM2, Karan M3.
Biotechnic & histochemistry : official publication of the Biological Stain Commission.Biotech Histochem.2016 May 18:1-5. [Epub ahead of print]
Irisin was first identified in muscle cells. We detected irisin immunoreactivity in various organs of the crested porcupine (Hystrix cristata). In the epidermis, irisin immunoreactivity was localized mainly in stratum basale, stratum spinosum and stratum granulosum layers; immunoreactivity was not o
PMID 27192184

Sebaceous lipids are essential for water repulsion, protection against UVB-induced apoptosis and ocular integrity in mice.

Dahlhoff M1, Camera E2, Schäfer M3, Emrich D4, Riethmacher D5, Foster A6, Paus R6, Schneider MR7.
Development (Cambridge, England).Development.2016 May 15;143(10):1823-31. doi: 10.1242/dev.132753. Epub 2016 Mar 17.
Sebocytes, which are characterized by lipid accumulation that leads to cell disruption, can be found in hair follicle-associated sebaceous glands (SGs) or in free SGs such as the Meibomian glands in the eyelids. Because genetic tools that allow targeting of sebocytes while maintaining intact epiderm
PMID 26989175

Japanese Journal